12-HYDROXY STEARIC ACID

12-Hydroxy Stearic Acid = 12-HSA

CAS Number: 106-14-9
EC Number: 203-366-1
Molecular Weight: 300.48
Molecular formula: C18H36O3

12-Hydroxy Stearic Acid (12-HSA) is a waxy, castor-derived fatty acid that finds use in lithium complex grease and other high performance greases with automotive and industrial applications. 
12-HAS is an efficient viscosity builder and gelling agent, and will gel hydrocarbons as well as many esters and some silicones. 
Salts made from 12-HSA can function as oil/water emulsifiers. 
12-HSA can be used as an emollient in underarm deodorant sticks, gel lipsticks, hair styling products, creams and lotions.
12-Hydroxy Stearic Acid is a castor oil derivative used in a variety of cosmetic applications. 
12-Hydroxy Stearic Acid is often used by formulators as an emollient in skin care products and is also a common surfactant in soaps. 
12-Hydroxy Stearic Acid is used predominately in antiperspirants and deodorants, lip gels, hair styling waxes, and skin creams and lotions

The castor oil derivative 12-hydroxystearic acid — also known as 12-hydroxy stearic acid or 12-HSA — can transform into a thickening agent in personal care products and as a chemical intermediate in chemical applications. 
From coatings and adhesives to sealants and elastomers, you’ll find an extensive variety of uses for this sustainable product. 
If you want to buy individual bags of 12-hydroxystearic acid, 18c by Acme-Hardesty offers top-quality solutions with low-quantity minimums. 
These products meet the needs of even small boutiques and testing center applications.
As one of the oldest and largest importers and distributors of Castor Oil in the US today, Acme-Hardesty Co., carries a full line of Castor Oil Derivatives including 12-Hydroxy Stearic Acid. 
12HSA is used as a chemical intermediate in coatings, adhesives, sealants and elastomers, as an activator and accelerator in the rubber manufacturing process and it is a key ingredient in the production of lithium greases. 
12-Hydroxy Stearic Acid is also used as an emollient in some personal care applications.

Uses of 12-Hydroxy Stearic Acid:
-As a Surfactant
-Thickener in Cosmetics
-In Lubricant Production
-Manufacturing of plastic products

WHAT IS 12-HYDROXYSTEARIC ACID?
Standard-grade 12-HSA is a saturated fatty acid produced by hydrogenating castor oil, which is naturally derived from castor beans. 
The oil’s double bonds are saturated as a result of hydrogenation, producing stearic acid. 
Manufacturers perform the process at room temperature using pressure and an alcohol solvent.
You may recognize the ingredient by 12-Hydroxy Stearic Acids light color and high melting point. 
12-Hydroxy Stearic Acid’s entirely sustainable and vegetable-based — perfect for environmentally friendly products and practices.

BENEFITS AND USES OF 12-HYDROXYSTEARIC ACID
Standard-grade 12-HSA is incredibly versatile, useful in applications spanning personal consumer products and industrial purposes. 
12-Hydroxy Stearic Acids benefits are best described when the product is broken down into 12-Hydroxy Stearic Acids two main uses — personal care and chemical applications.

12-HYDROXYSTEARIC ACID IN PERSONAL CARE APPLICATIONS
Skin care product manufacturers have long favored 12-HSA for 12-Hydroxy Stearic Acids emollient, surfactant and thickening properties. 
In fact, cosmetics and personal care are the most common applications of the ingredient. 

You’ll find hydroxystearic acid in the ingredients list of products such as:
-Lotions, gels and creams
-Makeup products
-Sun lotions and tanning creams
-Hair care products like shampoos and conditioners
-Deodorants and antiperspirants
-Facial cleansers and other body care products

Choosing 12-HSA as an ingredient in your personal care products offers a wide range of benefits. 
Some of its unique advantages include:
Safety: 12-hydroxy stearic acid is a low-risk substance that won’t irritate skin or harm the body. 
12-Hydroxy Stearic Acid also does not come into contact with any common allergens during manufacturing. 
These qualities make 12-Hydroxy Stearic Acid an excellent choice for consumers and a low-risk option for manufacturers.
Eco-friendliness: 12-Hydroxystearic acid is also an eco-friendly alternative to many traditional makeup products. 
The ingredient is derived from entirely natural sources and is sourced sustainably.
Versatility: You can use 12-HSA in nearly any personal care product, which means even a single bag of the substance will be well worth the cost.

12-HYDROXYSTEARIC ACID IN CHEMICAL APPLICATIONS
Standard-grade 12-HSA is praised for its numerous chemical qualities. 
12-Hydroxy Stearic Acids waxiness makes 12-Hydroxy Stearic Acid ideal for creating long-lasting greases for the automotive industry and industrial applications. 
Most greases and lubricants available today use some form of the product.
12-hydroxystearic acid is also widely available for CASE applications. 
When reacted with acrylic esters, 12-Hydroxy Stearic Acid produces strong polymers for a lustrous finish you can use to coat automotive and industrial machinery.

12-Hydroxystearic acid, also known as 12-hydroxy-octadecanoate or DL-12-hydroxy stearate, belongs to the class of organic compounds known as long-chain fatty acids. 
These are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms. 
12-Hydroxystearic acid is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral.

12 Hydroxystearic Acid 12HSA is a waxy hydroxyl fatty acid that is odorless and tasteless. 
12-Hydroxy Stearic Acid is primarily used in grease, lubricant, cosmetics, paint, and rubber industries. 
12-Hydroxy Stearic Acid is soluble in many organic solvents but insoluble in water.

Features and Benefits
12-Hydroxy Stearic Acid is primarily used in Grease and Lubricants manufacturing.
12-Hydroxy Stearic Acid enhances the overall performance with better texture, improved heat stability and improved dropping points.
12-Hydroxy Stearic Acid has excellent heat tolerance and water resistance.
 
Application
In the cosmetics industry, 12-Hydroxy Stearic Acid is used for gelling liquid petroleum to produce brilliance. 
12-Hydroxy Stearic Acid is also incorporated into cold creams and vanishing creams to give a jelly-like feeling.
In paints industry 12-Hydroxy Stearic Acid is reacted with acrylic esters to produce hard, durable thermosetting polymers used in high-quality automotive, industrial appliance and metal decorative finishes.
In rubbers industry, 12-Hydroxy Stearic Acid functions as an activator and internal lubricant for natural and synthetic rubbers.

GRADES AVAILABLE
Technical

SYNONYMS
Hydroxystearic Acid, Hydrogenated Fatty Acids

Precaution:
Store in a dry, well-ventilated area. 
Keep container closed. 
Keep away from heat, sparks, and flames.

Product Description
12-Hydroxy Stearic Acid is the mixed fatty acid obtained by hydrolysis of Hydrogenated Castor Oil. 
12-Hydroxy Stearic Acid is high melting, brittle, waxy solid at ambient temperatures. 
12-Hydroxy Stearic Acid should be stored away from heat to avoid deterioration.
12-Hydroxy Stearic Acid is insoluble in water and 12-Hydroxy Stearic Acid's solubility in many organic solvents is also limited. 
12-Hydroxy Stearic Acid is a non-toxic, non-hazardous material. 
12-Hydroxy Stearic Acid is used in the manufacturing of greases.

Synonyms: 12-Hydroxyoctadecanoic acid, 12-Hydroxystearic acid, 12-HSA
Linear Formula: CH3(CH2)5CH(OH)(CH2)10COOH
CAS Number: 106-14-9
Molecular Weight: 300.48

12-Hydroxystearic Acid is a C18 straight chain fatty acid 12-Hydroxystearic Acid uses and applications include: 
-Emulsifier; 
-major component in lithium greases; 
-chemical intermediate; 
-lubricant for PVC and plastics processing; 
-emulsifier, cleansing agent, surfactant in cosmetics, toiletries; wax blends; 
-polishes; 
-inks; 
-hot-melt adhesives; 
-paints; 
-thickener; 
-defoamer in food-contact paperpaperboard; 
-in lubricants for incidental food-contact use.

Uses of 12-Hydroxy Stearic Acid:
Plastics processing and production: 12-HSS is used as an additive in the production of PVC products (films, sheets, window profiles, wall panels, siding, etc.). 
12-HSA is an additive part (these are different substances and components which are used for the superheat reduction in cylinders of the processing units and provide good sliding of the melts)
Lubricants: 12-HSA can be used in lithium, barium and calcium-free high quality glycerol lubricants. 
These lubricants are predestined for airplanes and cars; they are water-, oil- and temperature resistant;
Cosmetics and perfume: 12-HSA can be used in the production of liquid vaseline, is used as a component of cosmetic creams;
Coating compounds: 12-HSA reacts to acrylates in the production of stable thermoreactive polymers, which are used in the production of automechanical and industrial plants of high quality and metallic decorative layers.
Production of packaging materials that contact with food.

Rubber products: 12-HSA is used as an activating agent and internal lubricant in the production of natural and synthetic rubber products.
Other products: 12-HSA is used as a component in polishing agents, printing ink, fusible adhesives and as a hydroxylated substitute for stearic acid.

Color: White
Melting Point: 72°C to 76°C
Linear Formula: CH3(CH2)5CH(OH)(CH2)10CO2H
Beilstein: 1726730
Solubility Information: Soluble in ether,alcohol and chloroform. Insoluble in water.
Formula Weight: 300.48
Physical Form: Crystalline
Percent Purity: 95%
Chemical Name or Material: 12-Hydroxystearic acid

Hydroxystearic Acid as a Surfactant
By itself, water is not the most effective cleaning agent.
While water loosens dirt and debris, 12-Hydroxy Stearic Acid is repelled by grease and oil — to help water clean effectively, another substance must be added to the water to lower its surface tension. This is why surfactants are essential in cleaning products. 
Designed to reduce the surface tension of water, surfactants help water molecules interact with grease and oil.
Surfactants work by using opposing forces. 
These cleansing molecules have a hydrophilic head and a hydrophobic tail, and both components are essential for a surfactant to work effectively — the hydrophilic head binds to water molecules, while the hydrophobic tail binds to dirt and oils. 
The hydrophobic tail also repels water molecules, creating more space and reducing the overall surface tension of the liquid.
As a surfactant, hydroxystearic acid helps water mix with oils and dirt. 
When used in cosmetic products, 12-HSA helps clean hair and skin of any grease or debris. 
Once loosened, the various oils and dirt are easily rinsed away, resulting in a fresh, clean surface.

12-HYDROXYOCTADECANOIC ACID
12-Hydroxystearic acid
106-14-9
Octadecanoic acid, 12-hydroxy-
Harwax A
DL-12-Hydroxystearic acid
Cerit Fac 3
Hydrofol acid 200
Ceroxin GL
Barolub FTO

Characteristics    12-Hydroxy stearic acid is a waxy hydroxy fatty acid with melting point is about 75ºC. 
12-Hydroxy Stearic Acid is obtained by saponifying hydrogenated castor oil.

12-Hydroxy stearic acid is soluble in most of warm organic solvents. 
12-Hydroxy Stearic Acids warmed solution of nonpolar solvent forms mild gel when cooled down.

A lithium salt of 12-Hydroxy stearic acid is most suitable as a density enhancer of higher multipurpose grease. 
In addition, 12-Hydroxy Stearic Acid is used as a raw material for cosmetic and oleo industry.

12-Hydroxy Stearic Acid is the mixed fatty acid obtained by hydrolysis of Hydrogenated Castor Oil. 
12-Hydroxy Stearic Acid is high melting, brittle, waxy solid at ambient temperatures. 
12-Hydroxy Stearic Acid should be stored away from heat to avoid deterioration.

12-Hydroxy Stearic Acid is insoluble in water and it's solubility in many organic solvents is also limited. 
12-Hydroxy Stearic Acid is a non-toxic, non-hazardous material. 
12-Hydroxy Stearic Acid is used in the manufacturing of greases.

Loxiol G 21
Stearic acid, 12-hydroxy-
12-hydroxy-octadecanoic acid
NSC 2385
DL-12-hydroxy stearic acid
36377-33-0
(R)-12-Hydroxyoctadecanoic acid
12-hydroxy stearic acid
MFCD00004592
CHEBI:85208
27924-99-8
KOW

Optically active 12-D-hydroxystearic acid (12-HSA) gives a thermally reversible organogel in several organic solvents. 
When a small amount of lecithin coexists with 12-HSA in organic solvents, the mechanical strength of the organogel is remarkably reduced. 
Interaction of lecithin with 12-HSA was studied by using infrared (IR) spectrometry, nuclear magnetic resonance (NMR) spectrometry, and scanning electron microscopy (SEM). 
Incorporating lecithin into 12-HSA reduced the absorbance in IR spectra, derived from hydrogen bonding between the hydroxyl groups and the carboxyl groups of 12-HSA molecules. 
Based on NMR measurements, the polar head groups of lecithin associate with the carboxyl groups of 12-HSA in a 1:1 molar ratio. 
SEM showed that the shape of the fibrous aggregates varied from a helically extended form to a spherical form. 
These results suggest that intermolecular 1:1 complexes were formed between lecithin and 12-HSA, which caused a structural change in the fibrous network in the 12-HSA organogel and consequently induced gel deformation.

Description
12-Hydroxy stearic acid (12-HSA) is a saturated hydroxy fatty acid. 
12-Hydroxy Stearic Acid is a waxy, odourless, tasteless and cream coloured compound in flakes / powder.
appearance: creamish flakes or powder
melting point °C min.: 70
colour Gardner max.: 6
colour (on 1” Lovibond) max 20 yellow / max. 4,5: red
acid value mg KOH/g min.: 175
iodine value (Wijs) g I2/100g max.: 5
hydroxyl value min.: 150
saponification value mg KOH/g: 175 - 190
Chemical Properties: white powder

Uses of 12-Hydroxy Stearic Acid:
lubrication: 12-Hydroxy stearic acid (12-HSA) gives better Lithium, Barium and Calcium multi-purpose greases. 
12-Hydroxy Stearic Acid provides excellent resistance to water, oils, solvents and crude petroleum, wide temperature range stability and high drop point.
cosmetics: 12-HSA is used for gelling liquid Paraffin in creams and ointments, which easily liquefy on the skin. 
Esters of 12-HSA are used in various cosmetic products (lipsticks, deodorant and antiperspirant sticks, shaving creams, etc.).
coatings: 12-HSA is reacted with acrylic esters to produce hard, durable thermosetting polymers used in the high quality automotive, industrial appliance and metal decorative finishes.
rubber: functions as an activator and internal lubricant for natural and synthetic rubbers
others: 12-HSA is an useful component in polishes, inks and hot melt adhesives
Lithium greases, chemical intermediates.

Definition
ChEBI: A hydroxy fatty acid that is stearic acid bearing a hydroxy substituent at position 12.

Sixteen different vinyl monomers were synthesised, based on 12‐hydroxy stearic acid in high purity. 
These include allyl, acrylic and methacrylic esters. 
These monomers were characterised by infra red spectroscopy and their purity was checked by chromatographic techniques. 
Boiling/melting points, refractive indices and iodine values of the products have been determined.

DSSTox_CID_6725
DSSTox_RID_78200
DSSTox_GSID_26725
CAS-106-14-9
HSDB 5368
12-Hydroxystearic acid homopolymer
EINECS 203-366-1
EINECS 253-004-1
UNII-YXH47AOU0F
(S)-12-Hydroxyoctadecanoic acid
BRN 1726730
AI3-19730
12-Hydroxystearic acid estolide
Octadecanoic acid, 12-hydroxy-, homopolymer
Polyhydroxystearic acid (2300 MW)
ACMC-1ACPY

12-Hydroxystearic acid (12-HSA) appended new amphiphilic scaffolds reveal excellent hydrogelation propensity in the presence of aqueous acids and vapors of HCl/HBr. 
This selective entrapment efficiency towards hydrogen halides demonstrates an unprecedented route for the successful removal of toxic chemicals, thus providing a safe and easy protocol for environment management. 
We anticipate that the halide derivative of the amphiphile plays a vital role in driving the self-assembly mechanism and eventually the hydrogelation phenomena.

Formula: C18H36O3
Molecular weight: 300.4766
IUPAC Standard InChI: InChI=1S/C18H36O3/c1-2-3-4-11-14-17(19)15-12-9-7-5-6-8-10-13-16-18(20)21/h17,19H,2-16H2,1H3,(H,20,21) 
InChI version 1.06
IUPAC Standard InChIKey: ULQISTXYYBZJSJ-UHFFFAOYSA-N 
CAS Registry Number: 106-14-9

HSA is an efficient, thixotropic viscosity builder that will gel hydrocarbons, many esters, and certain silicones. 
Can be used by formulators as a primary oil-in-water emulsifier. 
INCI: Hydroxystearic Acid
Form: Flake
Properties: Vegetable based. 
Gels hydrocarbons, many esters and certain silicones. 
Moisturizing via occlusivity and humectancy. 
Higher melting point than stearic acid.
Applications: Anhydrous pigmented lip gels, antiperspirants, cosmetic pencils, hair styling waxes, creams, lotions
Certifications: Ecocert and Cosmos approved and certified

12-hydroxy-stearic acid
YXH47AOU0F
EC 203-366-1
SCHEMBL17773
WLN: QV10YQ6
4-03-00-00942 (Beilstein Handbook Reference)
POLYHYDROXYSTEARIC ACID
12-HSA
CHEMBL292352
12 HYDROXY STEARIC ACID
DTXSID8026725
NSC2385
(?)-12-Hydroxyoctadecanoic acid
12-Hydroxyoctadecanoic acid, 99%
18417-00-0
5762-36-7
NSC-2385

Molecular formula: C18H36O3
Synonyms: Hydroxystearic Acid
International name: 12-Hydroxy Stearic Acid, 12-HSS
CAS-Nr.: 106-14-9
Qualification: Import
Appearance: flakes or powder
Storage: Store at room temperature in a dry place

12-Hydroxy Stearic Acid is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
12-Hydroxy Stearic Acid is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Consumer Uses
12-Hydroxy Stearic Acid is used in the following products: washing & cleaning products, adhesives and sealants, lubricants and greases, polishes and waxes, fertilisers, coating products and air care products.
Other release to the environment of 12-Hydroxy Stearic Acid is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

Article service life
Other release to the environment of 12-Hydroxy Stearic Acid is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).
12-Hydroxy Stearic Acid can be found in complex articles, with no release intended: vehicles.
12-Hydroxy Stearic Acid can be found in products with material based on: rubber (e.g. tyres, shoes, toys), stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys) and plastic (e.g. food packaging and storage, toys, mobile phones).
12-Hydroxy Stearic Acid is intended to be released from scented: clothes.

Widespread uses by professional workers
12-Hydroxy Stearic Acid is used in the following products: washing & cleaning products and polishes and waxes.
12-Hydroxy Stearic Acid is used in the following areas: formulation of mixtures and/or re-packaging.
12-Hydroxy Stearic Acid is used for the manufacture of: chemicals.
Other release to the environment of 12-Hydroxy Stearic Acid is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).

Formulation or re-packing
12-Hydroxy Stearic Acid is used in the following products: polymers, paper chemicals and dyes, lubricants and greases and textile treatment products and dyes.
Release to the environment of 12-Hydroxy Stearic Acid can occur from industrial use: formulation of mixtures and formulation in materials.

Uses at industrial sites
12-Hydroxy Stearic Acid is used in the following products: polymers, washing & cleaning products, textile treatment products and dyes, metal surface treatment products, pH regulators and water treatment products, leather treatment products and lubricants and greases.
12-Hydroxy Stearic Acid is used in the following areas: formulation of mixtures and/or re-packaging.
12-Hydroxy Stearic Acid is used for the manufacture of: chemicals, textile, leather or fur and plastic products.
Release to the environment of 12-Hydroxy Stearic Acid can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.

Manufacture
Release to the environment of this substance can occur from industrial use: manufacturing of the substance and as an intermediate step in further manufacturing of another substance (use of intermediates).
Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

CAS Number: 106-14-9
EINECS/ELINCS No: 203-366-1
COSING REF No: 34555
Chem/IUPAC Name: 12-Hydroxystearic acid

FEATURES
Solid flake at room temperature.
Non-regulated for storage and transport.
Versatility – 12-Hydroxy Stearic Acid is very versatile and can be used in many formulations including greases, polishes, plasticisers and cosmetics. 

12-Hydroxy stearic acid is a saturated fatty acid derived from hydrogenated castor oil.  
The hydroxyl groups are responsible for the unique properties and applications. 
12-Hydroxy stearic acid is a light coloured acid with a high melting point. 
12-Hydroxy Stearic Acid is soluble in solvents as isopropylalcohol, benzene, aceton etc. and is mainly used in the manufacture of lubricating greases as thickening agents. 
12-Hydroxy Stearic Acid is also used as a non-drying fatty acid in the manufacture of alkyd resins, as a PVC lubricant and mould release agent.

EINECS 227-283-5
EINECS 242-295-0
Tox21_201492
Tox21_303035
ANW-15316
LMFA02000130
AKOS016010128
MCULE-9965131742
NCGC00164350-01
NCGC00164350-02
NCGC00257021-01
NCGC00259043-01
8039-23-4
FT-0607234
ST51039859
V0108
W-108773
W-110875
Q27158401
12-Hydroxystearic acid, United States Pharmacopeia (USP) Reference Standard
Benzyl(2S,3aS,7aS)-octahydro-1H-indole-2-carboxylate4-methylbenezenesulfonate
78642-86-1

A comprehensive review of the features driving self-assembly of 12-hydroxystearic acid (12-HSA), a low-molecular-weight gelator, and its applications in drug delivery and as other soft innovative materials are presented herein. 
12-HSA is obtained via hydrogenation of ricinoleic acid naturally found in high concentrations in castor oil. 
The ability of 12-HSA to self-assemble is associated with the presence, position, and enantiomeric purity of the hydroxy group along the fatty acid chain. 

The polarity and position of the hydroxyl group facilitates more interaction possibilities leading to 12-Hydroxy Stearic Acids exceptional self-assembly behavior giving rise to fibers, ribbons, and tubes in a variety of solvents. 
Upon self-assembly, 12-HSA undergoes crystallization resulting in the formation of high aspect ratio fibrillar structures due to noncovalent, intermolecular interactions forming self-spanning, three-dimensional networks (called self-assembled fibrillar networks) in both aqueous and organic solvents. 
Herein, emphasis is placed on emerging applications of 12-HSA supramolecular assemblies (i.e. responsive aqueous foams, gelled complex fluids, drug delivery systems, hydrogels, organogels, xerogels, and aerogel). 
The vast literature is compiled associated with 12-HSA self-assembly exploring supramolecular assemblies based on one ambidextrous gelator capable of assembling in aqueous and nonaqueous solvent.

106-14-9 [RN]
12-HSA
12-Hydroxyoctadecanoic acid [ACD/IUPAC Name]
12-Hydroxyoctadecansäure [German] [ACD/IUPAC Name]
12-Hydroxystearic acid
253-004-1 [EINECS]
36377-33-0 [RN]
Acide 12-hydroxyoctadécanoïque [French] [ACD/IUPAC Name]
DL-12-hydroxy stearic acid
DL-12-hydroxystearic acid

Applications of 12-Hydroxy Stearic Acid:
The 12-Hydroxystearic acid sold by HENRY FRANC is a natural source (castor) used by the cosmetics industry, but also in other multiple industrial applications (lubricants, for example). 
12-HSA is a fatty acid used as a surfactant, thickener or emollient in personal care applications. 
12-Hydroxy Stearic Acid also finds use in lubricant formulations.

MFCD00004592 [MDL number]
Octadecanoic acid, 12-hydroxy- [ACD/Index Name]
WI3850000
[106-14-9]
[36377-33-0]
12 HYDROXY STEARIC ACID
12-(R,S)-HYDROXYSTEARIC ACID [9,10-3H]
12-?hydroxy-Octadecanoic acid
12-HAS

Overview of Hydroxystearic Acid
Also called 12-hydroxy stearic acid and 12-HSA, hydroxystearic acid is a fatty acid surfactant, emollient and thickener. 
Hydroxystearic acid is used widely in a variety of personal care and cosmetics products, including skin care preparations, hair products and deodorizing products.
Structurally similar to stearic acid, hydroxystearic acid is entirely vegetable-based and derived from naturally-occurring fats and oils, most commonly castor oil. 
12-HSA is synthesized by oxidizing 2-hexylcyclododecanone with a mixture of permaleic and peracetic acids in methylene chloride. 
This forms the lactone of hydroxystearic acid, and alkaline hydrolysis of the lactone produces 12-HSA.

Product Number: H0308
Purity / Analysis Method: >80.0%(GC)
Molecular Formula / Molecular Weight: C18H36O3 = 300.48  
Physical State (20 deg.C): Solid
CAS RN: 106-14-9
Reaxys Registry Number: 1726730
PubChem Substance ID: 87570730
SDBS (AIST Spectral DB): 2546
MDLNumber: MFCD00004592

Synonyms:
KOW;12-HSA;harwaxa;d-12HSA;Harwax A;ceritfac3;ceroxingl;loxiolg21;barolubfto;Ceroxin gl

Formal Name: 12-hydroxy-octadecanoic acid
CAS Number: 106-14-9
Synonyms: 
12-HSA
NSC 2385
Molecular Formula: C18H36O3
Formula Weight: 300.5
Purity: ≥95%
Formulation: A solid
Solubility: (Learn about Variance in Solubility)
DMF: 10 mg/ml
DMSO: 10 mg/ml
Ethanol: 10 mg/ml
SMILES: CCCCCCC(O)CCCCCCCCCCC(O)=O
InChi Code: InChI=1S/C18H36O3/c1-2-3-4-11-14-17(19)15-12-9-7-5-6-8-10-13-16-18(20)21/h17,19H,2-16H2,1H3,(H,20,21)
InChi Key: ULQISTXYYBZJSJ-UHFFFAOYSA-N

Castor oil is the source of numerous products and is the only commercial source of the fatty acid ricinoleate, 12-hydroxy-oleate. 
Hydrogenated castor oil is similarly useful as the source of 12-hydroxy-stearic acid, best known as a component of lithium grease. 
Mono- and diacylglycerols are derived from castor oil and are useful in development of lubricants and emulsifiers for cosmetics, pharmaceutical and food use. 
Acylglycerols derived from hydrogenated castor oil may be similarly useful, albeit with different physical and chemical properties. 
We have evaluated the use of immobilized lipases to generate acylglycerols, using organic solvents to modulate the action of lipase to produce mono- and diacylglycerols, using tri-(12-hydroxy stearoyl)-glycerol as a model for hydrogenated castor oil. 
The presence of an alkylated oxygen in the solvent appears to be an important factor in supporting lipase activity, with diisopropyl ether providing the best yield of di-(12-hydroxy stearoyl)-glycerol.

12-hydroxy stearic acid
12-Hydroxy-octadecanoic acid
12-hydroxystearic acid tech. grade
12-hydroxystearic acid, 95%
12-hydroxystearic acid, tech. 85%
12-Hydroxysteric acid
18417-00-0 [RN]
27924-99-8 [RN]
4-[(1R)-1-Hydroxyethyl]phenol [ACD/IUPAC Name]
4-03-00-00942 [Beilstein]
5762-36-7 [RN]
654637-88-4 [RN]
78642-86-1 [RN]
8039-23-4 [RN]
860114-96-1 [RN]

Vegetable oils due to high biodegradability, low toxicity, renewability and excellent lubricating performance, have immense potential to replace mineral oils as feedstock for lubricants. 
Owing to these aspects environmentalists and engineers have made attempts to explore the possibilities of using vegetable oils as environmentally friendly lubricants for range of applications. 
In this work, the tribological properties of castor oil and sesame oil in the presence of 12-hydroxystearic acid as anti-wear additive were investigated using four-ball tribometer. 
The viscosity, acid value, peroxide value and iodine value of the selected oils were determined experimentally following AOCS methods. 
Results revealed that the addition of 12-hydroxystearic acid improved the anti-wear performance of the selected vegetable oils. 
Moreover, it was noted from the results that 12-hydroxystearic acid was more effective as anti-wear additive in the castor oil as compared to sesame oil under similar experimental conditions. 
The improved anti-wear performance of the selected vegetable oils in the presence of additive may be attributed to the formation of protective layer as a result of tribochemical reaction on the metal surface.

Some of the most popular applications for hydroxystearic acid include the following products:
-Lotions
-Creams
-Gels
-Make-up and decorative cosmetics
-Hair care, such as shampoos, conditioners and styling products
-Skin care, such as facial care and cleansing, body care and baby care products
-SPF enhancement
-Sun care, such as sun protection, self-tanning and after-tanning products
-Underarm deodorants
-In any given cosmetics product, hydroxystearic acid is used in three primary functions — as a surfactant, emollient and thickener.

Formula: C18H36O3
Molecular weight: 300.4766
IUPAC Standard InChI: InChI=1S/C18H36O3/c1-2-3-4-11-14-17(19)15-12-9-7-5-6-8-10-13-16-18(20)21/h17,19H,2-16H2,1H3,(H,20,21) Copy
InChI version 1.06
IUPAC Standard InChIKey: ULQISTXYYBZJSJ-UHFFFAOYSA-N Copy
CAS Registry Number: 106-14-9

poly-12-hydroxy stearic acid (PTHSA) was synthesized and then modified by esterification with pentaerythritol to obtain a polyol polymeric hyperdispersant (polyol-PTHSA). 
Under suitable reaction conditions (molar ratio pentaerythritol/PTHSA, 1.2:1; reaction temperature, 453 K; and reaction time, 4−8 h), the polyol-PTHSA with acid value of 3 mg of KOH/g can be obtained. 
The structures were confirmed by FT-IR analysis. 
The polyol-PTHSA was subsequently used as a hyperdispersant in the process of preparing environmentally friendly overbased calcium oleate detergent to increase the total base number of the product. 
Reaction conditions including the polymerization catalyst, the catalyst amount, the amount of xylene, the polymerization temperature, the polymerization time, the polyol-PTHSA amount, and the acid value of the PTHSA were optimized.

CAS no.: 106-14-9
EC no.: 203-366-1
Molecul formula: C18H36O3
REACH status: 01-2119542189-34
Synonyms
12-HSA, 12-Hydroxystearic acid, 12-Hydroxyoctadecanoic acid
E-number / INCI name
E-570 / HYDROXYSTEARIC ACID

Hydroxystearic Acid is a fatty acid used as a surfactant–cleansing agent in cosmetic products. 

SYNONYM
Octadecanoic acid, 12-hydroxy-; Cerit Fac 3; Harwax A; Hydrofol Acid 200; Stearic acid, 12-hydroxy-; 12-Hydroxyoctadecanoic acid
Barolub FTO; Ceroxin GL; KOW; Loxiol G 21; DL-12-Hydroxystearic acid; NSC 2385;12-hydroxy-octadecanoicaci; 12-hydroxystearic
12-hydroxy-stearicaci; 12-Hydroxysteric acid; Barolub fto; barolubfto; Cerit Fac 3; ceritfac3;;Hydroxystearic acid;HSA
12-Hydroxyoctadecanoic acid; 12-Hydroxystearic acid; Octadecanoic acid, 12-hydroxy-

12-HSA is a useful component in hot-melt adhesives, inks and polishes, that reacts with acrylic esters to create durable and strong thermosetting polymers. 
These thermosetting polymers are used as a coating in metal-decorative finishes, industrial appliances and high-quality automotive applications.

Barolub FTO
Cerit Fac 3
Ceroxin GL
DL-12-HYDROXY STEARIC ACID|12-HYDROXYOCTADECANOIC ACID
Harwax A
Hydrofol acid 200
hydroxystearic acid
Jsp000562
KOW
lemosol coagulant
Loxiol G 21
stearic acid, 12-hydroxy-
tech., 85%
WLN: QV10YQ6

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