DOCUSATE SODIUM

CAS Number: 577-11-7
Molecular Weight: 444.56
EC Number: 209-406-4
E number: E480

Docusate Sodium is the sodium salt of docusate, a dioctyl salt and an emollient laxative with stool-softening activity. 
Docusate decreases surface tension and emulsification of fecal matter and allows water to penetrate and mix with stool. 
Docusate Sodium softens the stool.
Dioctyl sodium sulfosuccinate is an odorless colorless to white waxy solid.
Docusate Sodium is a Surfactant Laxatives class drug.

Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS).
Docusate Sodium is on the World Health Organization's List of Essential Medicines.
Salts of this anion, especially docusate sodium, are widely used in medicine as laxatives and as stool softeners, by mouth or rectally.
In 2019, Docusate Sodium was the 187th most commonly prescribed medication in the United States, with more than 3 million prescriptions.

What is docusate sodium?
Docusate sodium is the main ingredient in some stool softeners. 
Constipation affects the number of bowel movements a person usually has, and can cause gas and bloating. 
Docusate sodium is also found in many drugs and cosmetics. 
Docusate Sodium may also be found in multivitamins and in some prenatal vitamins. 
In general, docusate sodium is thought to stay in the gut with very little getting into the blood stream. 
If the medication is not in the blood stream, Docusate Sodium does not cross the placenta and the fetus/baby would not be exposed.

What is Docusate Sodium used for?
Docusate Sodium comes in capsule form and is used to treat constipation and reduce pain or rectal damage cause by straining during bowel movements. 
Docusate Sodium works by increasing the amount of water in stool, making it softer and easier to pass. 

What Form(s) Does Docusate Sodium Come In?
-Capsule
-Tablet
-Liquid
-Liquid Filled Capsule

General description of Docusate Sodium:
Docusate sodium (sodium dioctylsulfosuccinate, DOSS) is commonly used as a surfactant, food additive and stool softener.

Applications of Docusate Sodium:
Docusate sodium (DOSS, AOT) has been used in the preparation of the following:
-Luminescent ceramics (phosphors).
-Stock solution during the quantification of DOSS in sea food by using liquid chromatography tandem mass spectrometry (LC-MS/MS).
-AOT-water-isooctane reverse micelle system
Docusate Sodium has also been used in a study to understand its effect on protein bioactivity, when it is co-encapsulates with proteins in polymer based microsphere systems.
Forms reverse micelles in hydrocarbon solvents; Suitable for the solubilization of the major myelin transmembrane proteolipid

Docusate sodium is a nonionic surfactant that has stool-softening properties, which allow penetration of intestinal fluids into the faecal mass. 
Docusate Sodium also has weak stimulant properties. 
Docusate is available as capsules (DulcoEase, Dioctyl) or solution. 
Docusate Sodium can be given to children aged 6 months and older. 
Children between the age of 6 months and 2 years should take 12.5 mg (5 mL of Docusal paediatric solution) three times a day. 
For children aged between 2 and 12 years, the dose is 12.5 to 25 mg (5–10 mL) three times a day. 
Adults and children older than 12 years should take up to 500 mg daily in divided doses. 
In contrast to liquid paraffin, docusate sodium seems to be almost free of any side effects. 
Docusate sodium can be given to all patient groups.

Some studies claim that docusate is not more effective than a placebo for improving constipation.
Other docusate salts with medical use include those of calcium and potassium.
Docusate salts are also used as food additives, emulsifiers, dispersants, and wetting agents, among other uses.

Docusate sodium and Docusate Calcium are used extensively in stool softener formulations to provide consistent, predictable, and gentle relief. 
This highly effective and versatile anionic surfactant (surface active agent) is used as an active ingredient in a variety of combination laxative/stool softener formulations. 
Our pharmaceutical-grade Docusate products are manufactured to the highest quality standards under cGMP, and offer exceptional quality and performance as active ingredients.

APPLICATIONS of Docusate Sodium:
Docusate is particularly effective as an active ingredient in:
-Laxatives & stool softeners – for prevention and treatment of various types of constipation, can be used alone or as an adjuvant with other laxatives, with a typical usage level of 0.1-1.0 % by weight
-Prenatal & geriatric vitamin preparations – to overcome constipation induced by iron salts
-Colon cleansing aids – in preparation of a patient for X-ray examination or surgery
-Ear wax removal – acts as a wetting agent to soften compacted wax

FEATURES of Docusate Sodium:
-Pharmaceutical grade, manufactured under cGMP ; EP and USP compliant
-Virtually free from adverse reactions when used in recommended doses
-Effective alone or in combination with peristaltic stimulants and bulking agents
-Docusate comes in 4 product forms:
-Docusate Sodium 100% waxy material and 85% powder (Docusate Granular) for tablets
-Docusate Sodium 50% in PEG 400 and Docusate Calcium 50% in Corn Oil for softgels

BENEFITS of Docusate Sodium:
-Meets standards of quality, strength, purity, and potency recognized worldwide
-Causes the least possible disturbance of normal body physiology; non habit-forming
-Allows ability to optimize formulations and enhance performance results
-Multiple product types provide flexibility in handling and ease of use.

How Does Docusate Sodium Work?
Docusate sodium works by increasing the amount of water stool absorbs from the gastrointestinal tract. 
This softens stool, making it easier to pass. 
When experiencing constipation, the stool can become hard and dry, and the additional moisture docusate absorbs into stool keeps it moist and moving smoothly through the bowel.

In addition, Docusate Sodium’s not healthy to strain when passing stool. 
Straining can lead to other complications such as hemorrhoids and anal fissures. 
Keeping stool soft through the use of docusate not only helps relieve constipation but also helps to prevent these uncomfortable and painful conditions.

History of Docusate Sodium:
Sodium docusate was patented in 1937 by Coleman R. Caryl and Alphons O. Jaeger for American Cyanamid, which commercialized it for many years as a detergent under the brand name Aerosol OT.
Docusate Sodiums use for the treatment of constipation was first proposed in 1955 by James L. Wilson and David G. Dickinson, and quickly popularized under the name Doxinate.

Medical use of Docusate Sodium:
The main medical use of docusate sodium is to treat constipation, acting as a laxative and stool softener. 
In painful anorectal conditions such as hemorrhoid and anal fissures, Docusate Sodium can help avoid pain caused by straining during bowel movements.
When administered by mouth, a bowel movement often occurs in 1 to 3 days, while rectal use may be effective within 20 minutes.
Sodium docusate is recommended as a stool softener for children.

However, Docusate Sodiums effectiveness for constipation is poorly supported by evidence.
Multiple studies have found docusate to be no more effective than a placebo for improving constipation.
Others have found Docusate Sodium to be less useful for the treatment of chronic constipation than psyllium.
The medication may be given to people who are receiving opioid medication, although prolonged use may cause irritation of the gastrointestinal tract.

Other medical uses of Docusate Sodium:
Docusate sodium, when used with ear syringing, may help with earwax removal, particularly in the case of impaction.
Sodium docusate is also used as a lubricant in the production of tablets and as an emulsifier in topical preparations and other suspensions.

Although the detergent dioctyl sodium sulfosuccinate (docusate sodium) is available as a stool softener, further studies of its efficacy are needed. 
The compound stimulates fluid secretion by the small and large intestines but does not increase the volume of ileostomy output or the weight of stools in normal subjects.
A double-blind crossover trial showed benefit in 5 of 15 older constipated subjects, as judged by patients and their caregivers, and a significant increase in bowel frequency.
In a multicenter double-blind randomized trial in adults, however, docusate sodium was less effective than psyllium for treating chronic idiopathic constipation.

Precautions and contraindications of Docusate Sodium:
Docusate sodium is approved and recommended as safe during pregnancy and breastfeeding.
Docusate is not recommended in people with appendicitis, acute abdomen, or ileus.
When taken by mouth Docusate Sodium should be ingested with plenty of water.

Docusate sodium is a versatile surfactant that is used as an active pharmaceutical ingredient (API) for a variety of laxative and stool softener formulations, where it is appropriate for capsules, tablets or liquid preparations. 
Docusate sodium can be used alone or in combination with peristaltic stimulants and bulking agents and in prenatal and geriatric iron preparations to counteract potential constipation induced by the consumption of iron salts.

WHAT IS DOCUSATE AND HOW DOES IT WORK?
Docusate is used to treat occasional constipation. 
Some medications and conditions can make constipation more likely. 
Stool softeners such as docusate are often the first method used for preventing and treating this type of constipation. 
Docusate is often used when straining to have a bowel movement should be avoided (e.g., after a heart attack or surgery).

Docusate is a stool softener.
Docusate Sodium works by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass.

Interactions of Docusate Sodium:
Docusate might increase resorption of other drugs, for example, dantron (1,8-dihydroxyanthraquinone).

Mechanism of action:
Docusate is an anionic surfactant, which works by reducing the surface tension of the stool, allowing more intestinal water and fat to combine with the stool.
This decreases the strain and discomfort associated with constipation.
Docusate Sodium does not stay in the gastrointestinal tract, but is absorbed into the bloodstream and excreted via the gallbladder after undergoing extensive metabolism.
The effect of docusate may not necessarily be all due to its surfactant properties. 
Perfusion studies suggest that docusate inhibits fluid absorption or stimulates secretion in the portion of the small intestine known as the jejunum.

Other uses of Docusate Sodium:
Dioctyl sodium sulfosuccinate is used as a surfactant in a wide range of applications, often under the name Aerosol-OT.
Docusate Sodium is unusual in that it is able to form microemulsions without the use of co-surfactants, and it has a rich variety of aqueous-phase behavior including multiple liquid crystalline phases.

Docusate Sodium as Food additive:
Dioctyl sodium sulfosuccinate has been approved by the US FDA as a "generally recognized as safe" (GRAS) additive.
Docusate Sodium is used in a variety of food products, as a surface active agent, stabilizer, thickener, wetting agent, processing aid, solubilizing agent, emulsifier, and dispersant. 
The highest amount found in food products is 0.5% by weight, which include pasteurized cheese spreads, cream cheeses and salad dressings.
The FDA also approved its use as a wetting agent or solubilizer for flavoring agents in carbonated and non-carbonated drinks at levels up to 10 parts per million.

Microencapsulation:
Sodium docusate is the most widely used surfactant in reverse micelle encapsulation studies.

Chemistry of Docusate Sodium:
Structure and properties:
The structural formula of the docusate anion is R−O−C(=O)−CH(SO−3)−CH2−C(=O)−O−R, where R is the 2-ethylhexyl group H3C−(CH2)3−C(−CH2−CH3)H−CH2−. 
The conjugate acid can be described as the twofold carboxylate ester of sulfosuccinic acid with 2-ethylhexanol.

Docusate Sodium is a white, wax-like, plastic solid, with an odor suggestive of octyl alcohol. 
Docusate Sodium starts to decompose at about 220 °C.

Solubility of dioctyl sodium sulfosuccinate in water is 14 g/L at 25 °C, increasing to 55 g/L at 70 °C.
Solubility is better in less polar solvents: 1:30 in ethanol, 1:1 in chloroform and diethylether, and practically unlimited in petroleum ether (25 °C). 
Docusate Sodium also is highly soluble in glycerol, although this is a rather polar solvent. 
Docusate Sodium is also highly soluble in xylene, oleic acid, acetone, diacetone alcohol, methanol, isopropanol, 2-butanol, methyl acetate, ethyl acetate, furfurol, and vegetable oils.
The ester groups are easily cleaved under basic conditions, but are stable against acids.

Synthesis of Docusate Sodium:
Sodium dioctyl sulfosuccinate can be obtained by treating dioctyl maleate with sodium bisulfite. 
The bisulfite anion adds to the double bond:
−CH=CH− + HSO−3→ −CH(−SO−3)−CH2−

Uses of Docusate Sodium:
Docusate Sodium is used to treat occasional constipation. 
Some medications and conditions can make constipation more likely. 
Stool softeners such as docusate are often the first method used for preventing and treating this type of constipation. 
Docusate is often used when straining to have a bowel movement should be avoided (such as after a heart attack or surgery).
Docusate is a stool softener. 
Docusate Sodium works by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass.

What is Docusate?
Docusate is a common medication for relieving constipation. 
Docusate Sodium is a stool softener. 
Docusate Sodium works by lowering the surface tension of the stool by allowing more water and fat to get mixed in the intestines, making it easy for the hard stool to pass. 
Docusate Sodium also works by reducing water reabsorption and increasing fluid secretion in the small intestine. 
After that, the docusate gets absorbed into the blood and metabolized before it is excreted through the gallbladder.

What are the uses of Docusate?
Docusate is commonly available as an over-the-counter laxative or stool softener. 
Docusate Sodium is indicated when there is any constipation like hard stools or opioid-induced constipation. 
Docusate Sodium is also effective in patients suffering from conditions like anal fissures and hemorrhoids that cause pain while trying to pass the stool. 
However, multiple studies like this have found that docusate is not as effective because a placebo given in its place showed the same results. 
There are a few other uses of docusate, such as removing ear wax and making other tablets.

How to use Docusate Sodium
Follow all directions on the product package unless otherwise directed by your doctor. 
If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth, usually at bedtime with a full glass (8 ounces or 240 milliliters) of water or juice, or as directed by your doctor. 
The dosage is based on your medical condition and response to therapy. 
Decrease your dose or stop taking this medication if you develop diarrhea.

If you are using the liquid form of Docusate Sodium, measure the dose carefully using a special measuring device/spoon. 
Do not use a household spoon because you may not get the correct dose. 
If you are using the drops, measure the medication with the dropper provided, or use a dose-measuring spoon or device to make sure you have the correct dose. 
Mix the syrup, liquid or drops in 4 to 8 ounces of fruit juice, milk or infant formula to prevent throat irritation and mask a bitter taste.

Use Docusate Sodium only when needed. 
Do not use this product for more than 1 week unless directed by your doctor.

What is docusate?
Docusate is a stool softener that makes bowel movements softer and easier to pass.
Docusate is used to relieve occasional constipation (irregularity).
There are many brands and forms of docusate available. 
Not all brands are listed on this leaflet.
Docusate may also be used for purposes not listed in this medication guide.

What is Docusate Sodium?
DOCUSATE SODIUM; SENNA (doc CUE sayt SOE dee um; SEN na) contains a stool softener and a laxative.
Docusate Sodium is used to treat constipation.
Docusate Sodium may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take Docusate Sodium?
They need to know if you have any of these conditions:
-blockage in your bowel
-inflammatory bowel disease
-stomach or intestine problems
-sudden change in bowel habits lasting more than 2 weeks
-vomiting
-an unusual or allergic reaction to docusate, senna, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

What are the Different Forms of Docusate Sodium?
How to use docusate sodium depends on whether it’s administered orally or rectally.
When consumed orally as a capsule or tablet, docusate is typically taken at bedtime with a full glass of water (at least 8 oz).
Docusate sodium also comes in liquid form for oral consumption. 
If administered in this manner be sure to use the accompanying measuring device (and not a household spoon or other implement) to be sure you receive the correct dosage. 
You can mix the liquid with juice or other beverage to alleviate the somewhat bitter taste.

Pharmacodynamics:
Docusate sodium is a laxative and an anionic detergent that supposedly promotes incorporation of water and fats into stool through a reduction in surface tension, resulting in softer fecal mass. 
Docusate's onset of action is 6-72 hours orally and 2-15 minutes rectally. 
The effects of docusate are thought to be exerted locally in the jejunum.

Mechanism of action:
Recent studies suggest that docusate's mechanism of action is due largely to it's surfactant effect in the intestines, which allow fat and water into the feces to soften the stool.

Docusate’s mechanism of action was investigated in 1985 on healthy patients.
Docusate was added directly to the jejunum based on calculated concentrations of docusate in the jejunum.
At this concentration, there was an increase in secretion of water, sodium, chloride, and potassium as well as a decrease in absorption of glucose and bicarbonate.
Based on in vitro data, the authors suggested this effect was due to an increase in intracellular cyclic AMP either directly through docusate or E series prostaglandins.

Absorption:
Docusate is not absorbed systemically. 
As the actions of docusate are local and it is not absorbed, the pharmacokinetic parameters are not available9.

How docusate (Colace) works
Docusate (Colace) is a stool softener. 
Docusate Sodium draws water into your stool to make it softer, which helps relieve constipation.

What is docusate (Colace) used for?
Occasional constipation from hard, dry stools

Docusate sodium (dioctyl sodium sulfosuccinate) and docusate calcium (dioctyl calcium sulfosuccinate) act like detergents and are used to soften the stool when it is desirable to lessen the discomfort or the strain of defecation. 
These drugs are anionic surfactants that produce their effect by reducing the surface tension and allowing intestinal fluids and fatty substances to penetrate the fecal mass. 
They usually require 1 to 3 days to exert their full effect if used alone, but they may be combined with other laxatives in OTC preparations. 
These agents are not believed to interfere with the absorption of nutrients from the intestinal tract, and they are not appreciably absorbed. 
Docusate is frequently recommended for elderly patients because it is associated with so few side effects. 
Diarrhea and mild abdominal cramps are the only adverse effects reported.

How should I use Docusate Sodium?
Take Docusate Sodium by mouth with a full glass of water. 
Follow the directions on the product label. 
Take exactly as directed. 
Do not take your medicine more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. 
While this medicine may be prescribed for children as young as 2 years for selected conditions, precautions do apply.

What is docusate and senna?
Docusate is a stool softener. 
Senna is a laxative.
Docusate and senna is a combination medicine used to treat occasional constipation.
Docusate and senna may also be used for purposes not listed in this medication guide.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

WHAT Docusate Sodium DOES: Prevents constipation.

HOW Docusate Sodium WORKS: Mixes with bowel contents to soften stool and make it easier for you to pass.

HOW TO TAKE Docusate Sodium: 
Take as directed. 
Usually this is used to prevent constipation from occurring but may be also used as treatment in combination with a laxative. 
If you are only taking this once per day, it is often best taken at bedtime. 
Do not take with mineral oil laxatives.

agency: meets USP testing specifications
Quality Level: 200
description: anionic
assay: 99.0-100.5% anhydrous basis
mol wt: 444.56 g/mol
technique(s): protein quantification: suitable
application(s):
detection
pharmaceutical (small molecule)
SMILES string: [Na+].CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S([O-])(=O)=O
InChI: 1S/C20H38O7S.Na/c1-5-9-11-16(7-3)14-26-19(21)13-18(28(23,24)25)20(22)27-15-17(8-4)12-10-6-2;/h16-18H,5-15H2,1-4H3,(H,23,24,25);/q;+1/p-1
InChI key: APSBXTVYXVQYAB-UHFFFAOYSA-M

Docusate sodium belongs to the family of medications known as stool softeners.
Docusate Sodium is used to treat and prevent occasional constipation due to hard stools. 
Docusate sodium works by increasing the amount of water in the stool, making stools softer and easier to pass. 
Docusate Sodium usually starts to work within 1 to 3 days, but it may take up to 5 days to work.

Docusate Sodium may be available under multiple brand names and/or in several different forms. 
Any specific brand name of Docusate Sodium may not be available in all of the forms or approved for all of the conditions discussed here. 
As well, some forms of Docusate Sodium may not be used for all of the conditions discussed here.

Your doctor may have suggested Docusate Sodium for conditions other than those listed in these drug information articles. 
If you have not discussed this with your doctor or are not sure why you are taking Docusate Sodium, speak to your doctor. 
Do not stop taking Docusate Sodium without consulting your doctor.

What if I miss a dose of Docusate Sodium?
If you miss a dose, take it as soon as you can. 
If Docusate Sodium is almost time for your next dose, take only that dose. 
Do not take double or extra doses.

Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation. 
Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass. 
Docusate can be orally or rectally administered. 
Docusate is on the World Health Organization's List of Essential Medicines. 
However the effectiveness of docusate in treating constipation remains unclear, as several studies report docusate to be no more effective than placebo for increasing the frequency of stool or stool softening.
Recently there has been pressure to stop prescribing docusate as it has been identified as an ineffective medicine. 
Additionally, Docusate Sodium does not appear to lessen symptoms associated with constipation such as abdominal cramps. 
Still docusate is available in over-the-counter products as a common laxative.

What may interact with Docusate Sodium?
This list may not describe all possible interactions. 
Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. 
Also tell them if you smoke, drink alcohol, or use illegal drugs. 
Some items may interact with your medicine.

What should I watch for while using Docusate Sodium?
Do not use for more than 1 week unless otherwise directed by your doctor or health care professional.

Stop using Docusate Sodium and contact your doctor or health care professional if you have rectal bleeding or do not have a bowel movement after use. 
These could be signs of a more serious condition.

Trade names: Colace, Ex-Lax Stool Softener, others
Other names: Dioctyl sulfosuccinate

Synonym(s):
Docusate sodium salt
Sulfosuccinic acid bis(2-ethylhexyl) ester sodium salt
AOT
Sodium bis(2-ethylhexyl) sulfosuccinate
Sulfobutanedioic acid bis(2-ethylhexyl ester) sodium salt
‘Dioctyl’ sulfosuccinate sodium salt
Bis(2-ethylhexyl) sulfosuccinate sodium salt

Docusate sodium
577-11-7
Dioctyl sodium sulfosuccinate
Dioctyl sulfosuccinate sodium salt
Aerosol OT
Constonate
Docusate (Sodium)
Docusate sodium salt
Diox
Manoxol OT
Bis(2-ethylhexyl) sulfosuccinate sodium salt
Colace
Dioctyl sulfosuccinate sodium
Sodium bis(2-ethylhexyl) sulfosuccinate
UNII-F05Q2T2JA0
Bis(2-ethylhexyl) sodium sulfosuccinate
Dioctyl ester of sodium sulfosuccinic acid
sodium 1,4-bis[(2-ethylhexyl)oxy]-1,4-dioxobutane-2-sulfonate
Dioctyl
F05Q2T2JA0
sodium docusate
MFCD00012455
AOT
Diomedicone
Clestol
Complemix
Defilin
Dialose
Dioctlyn
Dioctylal
Diosuccin
Disonate
Doxinate
Dulsivac
Laxinate
Mervamine
Molatoc
Molofac
Regutol
Requtol
Sobital
Soliwax
Coprol
Diovac
Konlax
Kosate
Molcer
Obston
Softil
Velmol
Waxsol
Butanedioic acid, sulfo-, 1,4-bis(2-ethylhexyl) ester, sodium salt
Nevax
Revac
Modane Soft
DSSTox_CID_2959
Alcopol O
Alphasol OT
Manoxal OT
Sulfimel DOS
Aerosol AOT
Aerosol GPG
Wetaid SR
DSSTox_RID_76808
Aerosol OT-A
DSSTox_GSID_22959
Laxinate 100
Sanmorin OT 70
Triton GR 7
Triton GR-5
Sulfosuccinic acid bis(2-ethylhexyl) ester sodium salt
Aerosol OT 70PG
Aerosol OT 75
Celanol DOS 65
Celanol DOS 75
DESS
Humifen WT 27G
Monawet MD 70E
Solusol-75%
Nikkol OTP 70
Aerosol A 501
Alkasurf SS-O 75
Solusol-100%
Nekal WT-27
Adekacol EC 8600
Berol 478
Coloxyl
Docolace
Docuprene
Geriplex
sodium;1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate
Silace
Unilax
Bloat treatment
Docusato sodico
Docusate sodique
Dialose Plus
Natrii dioctylsulfosuccinas
Tex-Wet 1001
Senokot S
Butanedioic acid, 2-sulfo-, 1,4-bis(2-ethylhexyl) ester, sodium salt (1:1)
Correctol Caplets
Correctol Tablets
Senokap DSS
Docusatum natricum
D-S-S
Doc Q Lace
CAS-577-11-7
Sodium dioctyl sulphosuccinate
Feen-a-Mint Pills
Correctol Extra Gentle Tablets
Docusate sodique [INN-French]
Docusato sodico [INN-Spanish]
Docusatum natricum [INN-Latin]
HSDB 3065
2-Ethylhexyl sulfosuccinate sodium
NCGC00164140-03
EINECS 209-406-4
SV 102
Bis(2-ethylhexyl)sodium sulfosuccinate
Dioctyl ester of sodium sulfosuccinate
Di-(2-ethylhexyl) sodium sulfosuccinate
Sodium di-(2-ethylhexyl) sulfosuccinate
Dioctyl sodium sulphosuccinat
Prenexa
Purgasol
Vinacol
Bis(2-ethylhexyl) S-sodium sulfosuccinate
AI3-00239
Docusate Sod
Sodium 1,4-bis(2-ethylhexyl)sulfosuccinate
1,4-Bis(2-ethylhexyl) sodium sulfosuccinate
Sodium sulfodi-(2-ethylhexyl)-sulfosuccinate
Senexon-S
Folca[s care pme
Folcal DHA
Senna-S
Di(2-ethylhexyl)sulfosuccinic acid, sodium salt
Bis(ethylhexyl) ester of sodium sulfosuccinic acid
Bis-2-ethylhexylester sulfojantaranu sodneho [Czech]
Colace (TN)
Sodium di(2-ethylhexyl)sulfosuccinate
Sulfosuccinic acid, bis(2-ethylhexyl)ester sodium salt
Docusate sodium [USAN:USP:INN:BAN]
Sol sodowej sulfobursztynianu dwu-2-etyloheksylowego [Polish
Docusate sodium (USP)
Bis-2-ethylhexylester sulfojantaranu sodneho
Succinic acid, sulfo-, 1,4-bis(2-ethylhexyl) ester, sodium salt
NCGC00183136-01
Sodium 1,4-bis(2-ethylhexyl) sulfosuccinate
EC 209-406-4
SCHEMBL4113
C20H37O7S.Na
MLS004773938
1,4-Bis(2-ethylhexyl)sulfobutanedioate, sodium salt
Sol sodowej sulfobursztynianu dwu-2-etyloheksylowego
CHEBI:4674
CHEMBL1905872
DTXSID8022959
Correctol Stool Softener Laxative
Sulfosuccinic acid, di-(2-ethylhexyl) ester, sodium salt
HMS3264P07
HMS3885B10
BCP31325
HY-B1268
4-(4-Bromophenoxymethyl)benzoicacid
Aerosol™ OT, Solid Anhydrous
Dioctyl sodium sulfosuccinate (JAN)
Sodium dioctyl sulfosuccinate (INN)
Tox21_112087
Tox21_113469
Tox21_201342
Tox21_300496
s4588
DIOCTYL DISODIUM SULFOSUCCINATE
AKOS015901806
CCG-213234
CS-4813
NSC 760404
Sodium Di(2-ethylhexyl) Sulfosuccinate
Docusate sodium salt, BioXtra, >=99%
Dioctyl sulfosuccinate sodium salt, 96%
NCGC00164140-01
NCGC00254414-01
NCGC00258894-01
AS-13347
E480
H957
SMR001595510
Aerosol™ OT Solution, 10% (w/w)
Dioctyl Sodium Sulfosuccinate with Ethanol
Bis(2-ethylhexyl) sulfosuccinatesodium salt
Dioctyl sulfosuccinate sodium salt, >=97%
FT-0689234
D00305
Docusate sodium salt, p.a., 99.0-100.5%
E77584
24978-EP2287154A1
24978-EP2308848A1
24978-EP2314574A1
88565-EP2298076A1
88565-EP2298077A1
88565-EP2301353A1
88565-EP2305031A1
88565-EP2305034A1
88565-EP2305035A1
Docusate sodium salt, purum, >=96.0% (TLC)
Docusate sodium salt, BioUltra, >=99.0% (TLC)
Docusate sodium, meets USP testing specifications
Dioctyl Sodium Sulfosuccinate with Diethylene Glycol
Dioctyl Sodium Sulfosuccinate with Propylene Glycol
Q2815334
W-105447
F8880-5559
Sulfobutanedioic acid bis(2-ethylhexyl ester) sodium salt
Docusate sodium, British Pharmacopoeia (BP) Reference Standard
Docusate sodium, European Pharmacopoeia (EP) Reference Standard
sodium 1,4-bis(2-ethylhexyloxy)-1,4-dioxobutane-2-sulfonate
Docusate sodium, United States Pharmacopeia (USP) Reference Standard
Dioctyl Sodium Sulfosuccinate with Diethylene Glycol and Glycol Ethers
1,4-bis(2-ethylhexyl)sodiumsulfosuccinate pound>>Dioctyl sulfosuccinate sodium salt
 

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