Glutaric acid dialdehyde = Glutaric dialdehyde = Glutaric aldehyde
CAS Number: 111-30-8
EC Number: 203-854-4
Chemical formula: C5H8O2 / OHC(CH2)3CHO
Molecular Weight: 100.12
Glutaric acid dialdehyde, C5H8O2 or OCH(CH₂)₃CHO, is a transparent oily, liquid with a pungent odor.
Glutaric acid dialdehyde or 1,5-Pentanodione is a dialdehyde of low irritant power and strong action, of wide antimicrobial spectrum, that works due to Glutaric acid dialdehyde's oxidizing and breaking down action on the cell walls.
Glutaric acid dialdehyde is an organic compound with the formula (CH2)3(CHO)2.
The molecule consists of a five carbon chain doubly terminated with formyl (CHO) groups.
Glutaric acid dialdehyde is usually used as a solution in water, and such solutions exists as a collection of hydrates, cyclic derivatives, and condensation products, several of which interconvert.
Glutaric acid dialdehyde is an organic compound with the formula CH2(CH2CHO)2.
Glutaric acid dialdehyde consists of a five carbon chain doubly terminated with formyl (CHO) groups.
Glutaric acid dialdehyde is usually used as a solution in water, and such solutions exists as a collection of hydrates, cyclic derivatives, and condensation products, several of which interconvert.
Glutaric acid dialdehyde is used in leather treatments, chemical syntheses, x-ray film developers, paper manufacture and paper finishes, and as a preservative in paints and art paints.
Glutaric acid dialdehyde is used as an embalming fluid and in many biochemical applications such as tissue fixative in electron microscopy and as an aminereactive homobifunctional crosslinker.
Glutaric acid dialdehyde is mainly used in the high performance disinfection and/or sterilization of elements that cannot be disinfected and/or sterilized through conventional ways (vapor, dry heat, radiation, etc.).
Because Glutaric acid dialdehyde has two carbonyl group is reactive to primary amine groups (even as its hydrates), Glutaric acid dialdehyde can function as a crosslinking agent for any substance with primary amine groups and develop imine connected link.
Glutaric acid dialdehyde is a colorless, oily liquid with a sharp, pungent odor.
Glutaric acid dialdehyde is a dialdehyde comprised of pentane with aldehyde functions at C-1 and C-5.
Glutaric acid dialdehyde has a role as a cross-linking reagent, a disinfectant and a fixative.
Glutaric acid dialdehyde solution is a light yellow liquid.
Glutaric acid dialdehyde mixes with water.
Glutaric acid dialdehyde is a common fixative in biology.
Fixation occurs by crosslinking (creating covalent chemical bonds between proteins in/on cells).
USES AND APPLICATIONS OF Glutaric acid dialdehyde:
Glutaric acid dialdehyde is used as Disinfectant, biocide, tissue fixative, medicine (wart treatment); component of hydraulic fracturing (fracking) fluid.
Glutaric acid dialdehyde is used as a medication, preservative, disinfectant and fixative.
Glutaric acid dialdehydeis used to disinfect the surgical instruments as well as other items of hospitals.
Glutaric acid dialdehyde which is also utilized as a cold sterilant that can disinfect as well as clean heat-sensitive medical, dental and surgical equipment.
Glutaric acid dialdehyde is used for the sectors of chemical Processing, Gas and Oil.
Glutaric acid dialdehyde is a sort of corrosion inhibitor that can be used in several industrial and processing applications.
Glutaric acid dialdehyde is similar to another common cross-linking fixative, PFA.
Glutaric acid dialdehyde, also known as Glutaraldehyde or glutaral is an organic compound with the formula OCH(CH2)3CHO.
Being non-volatile and bifunctional, glutaraldehyde is often preferred to the less expensive formaldehyde.
Glutaric acid dialdehyde reacts with amines, amides, and thiol groups in proteins.
Glutaric acid dialdehyde, C5H8O2 or OCH(CH₂)₃CHO, is a transparent oily, liquid with a pungent odor.
Glutaric acid dialdehyde is an oily liquid at room temperature (density 1.06 g/mL), and miscible with water, alcohol, and benzene.
Glutaric acid dialdehyde is colorless to yellowish liquid with a pungent fruity/medicinal odor.
Glutaric acid dialdehyde is a 5-25% aqueous solution.
Glutaric acid dialdehyde's Physical properties are based on a 25% solution.
Glutaric acid dialdehyde is miscible with water, ethanol, benzene, ether, acetone, dichloromethane, ethylacetate, isopropanol, n-hexane and toluene.
Glutaric acid dialdehyde is a slightly irritating odor of colorless or yellowish clear liquid, Glutaric acid dialdehyde is soluble in water and ether, ethanol and other organic solvents.
The free form of Glutaric acid dialdehyde in aqueous solution is not much, a large number of different forms of hydrate, and most of the ring structure of the hydrate form exists.
Glutaric acid dialdehyde is active in nature, easy to polymerize and oxidize, and will react with compounds containing active oxygen and nitrogen-containing compounds.
Colorless liquid with a pungent odor; Clear, viscous colorless liquid; Light yellow liquid; Colorless or light yellow liquid with a sharp pungent odor; Commercially available in aqueous solutions ranging from 2-50%
Glutaric acid dialdehyde is soluble in water and in organic solvents.
Glutaric acid dialdehyde uses:
-Glutaric acid dialdehyde is used as An antimicrobial in water-treatment systems
-Glutaric acid dialdehyde is used as A slimicide in paper manufacturing
-Glutaric acid dialdehyde is used as A preservative in cosmetics
-Glutaric acid dialdehyde is used as A disinfectant in animal housing
-Glutaric acid dialdehyde is used as A tissue fixative in histology and pathology labs
-Glutaric acid dialdehyde is used as A hardening agent in the development of X-rays
-Glutaric acid dialdehyde is used as In embalming solutions
-Glutaric acid dialdehyde is used as In the preparation of grafts and bioprostheses
-Glutaric acid dialdehyde is used as In various clinical applications
Glutaric acid dialdehyde is a dialdehyde comprised of pentane with aldehyde functions at C-1 and C-5.
KEYWORDS:
111-30-8, 203-854-4, Glutaric dialdehyde, Glutaric aldehyde, 1 5-Pentanedial, Sonacide, Glutaric acid dialdehyde, 1 3-Diformylpropane, Novaruca, NCI-C55425
Solutions in water are stable for long periods of time.
Glutaric acid dialdehyde is colorless or yellowish clear and bright liquid with slight irritating smell, and can be dissolved in organic dissolvent such as water, ether and ethanol.
In water solution, Glutaric acid dialdehyde doesn't exist much in free state; instead, Glutaric acid dialdehyde makes appearance as hydrates with different forms and most of them are hydrates with annular structure.
Glutaric acid dialdehyde is reactive in property, and liable to polymerize and oxidize, which will react with compounds containing active oxygen and nitrogen.
The reaction of Glutaric acid dialdehyde with protein is mainly carried out between the carbonyl group of the former and the amino group of the latter.
Among the known aldehydes, Glutaric acid dialdehyde is one of the best cross-linking agents for proteins.
Glutaric acid dialdehyde has a small influence on the activity of enzyme, and most of enzymes can be fixed under controlled condition, to cross-link without losing their activity.
Contrbuting to its outstanding characteristics, Glutaric acid dialdehyde has drawn special concern from people and been put at broad application.
A dialdehyde comprised of pentane with aldehyde functions at C-1 and C-5.
Glutaric acid dialdehyde is a colorless liquid with a pungent odor used to disinfect medical and dental equipment.
Glutaric acid dialdehyde is an oily liquid at room temperature (density 1.06 g/mL), and miscible with water, alcohol, and benzene.
Because Glutaric acid dialdehyde has two carbonyl group is reactive to primary amine groups (even as its hydrates), Glutaric acid dialdehyde can function as a crosslinking agent for any substance with primary amine groups and develop imine connected link.
Glutaric acid dialdehyde is an extremely versatile disinfectant and biological tissue fixer.
Also know by its IUPAC name Glutaric acid dialdehyde, is a clear, pungent, and oily liquid that is miscible in water.
Glutaric acid dialdehyde is highly reactive with amines, amides, and thiols present in amino acid side chains, and most of its uses can be attributed to Glutaric acid dialdehyde's excellent protein crosslinking abilities.
Molecular Weight: 100.12
XLogP3-AA: -0.5
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 4
Exact Mass: 100.052429494
Monoisotopic Mass: 100.052429494
Topological Polar Surface Area: 34.1 Ų
Heavy Atom Count: 7
Formal Charge: 0
Complexity: 51.1
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Glutaric acid dialdehyde, an aliphatic dialdehyde, is a highly reactive compound that has been isolated as a water-soluble oil and usually is stored as an aqueous solution to inhibit polymerization.
Unbuffered aqueous solutions of Glutaric acid dialdehyde are stable for long periods of time, have a mildly acid pH, a negligible odor, and are not potently antimicrobial.
When buffered to an alkaline pH of 7.5 to 8.0 with sodium bicarbonate, Glutaric acid dialdehyde is activated; Glutaric acid dialdehyde has a strong pungent odor, and Glutaric acid dialdehyde's antimicrobial activity is greatly enhanced for periods of up to 14 days
Glutaric acid dialdehyde is an organic compound with the formula CH2(CH2CHO)2.
Glutaric acid dialdehyde is colorless or yellowish clear and bright liquid with slight irritating smell, and can be dissolved in organic dissolvent such as water, ether and ethanol.
In water solution, Glutaric acid dialdehyde doesn't exist much in free state; instead,it makes appearance as hydrates with different forms.and most of them are hydrates with annular structure.
Glutaric acid dialdehyde is reactive in property, and liable to polymerize and oxidize, which will react with compounds containing active oxygen and nitrogen.
The reaction of Glutaric acid dialdehyde with protein is mainly carried out between the carbonyl group of the former and the amino group of the latter.
Among the known aldehydes, Glutaric acid dialdehyde is one of the best cross-linking agents for proteins.
Glutaric acid dialdehyde has a small influence on the activity of enzyme, and most of enzymes can be fixed under controlled condition, to cross-link without losing their activity.
Contrbuting to Glutaric acid dialdehyde's outstanding characteristics, Glutaric acid dialdehyde has drawn special concern from people and been put at broad application.
USES AND APPLICATIONS OF Glutaric acid dialdehyde:
Glutaric acid dialdehyde is used as Disinfectant for surgical instruments that cannot be heat sterilized
Glutaric acid dialdehyde is used as A cross-linking and tanning agent
Glutaric acid dialdehyde is used as A biocide in metalworking fluids and in oil and gas pipelines
Glutaric acid dialdehyde is used as An antimicrobial in water-treatment systems
Glutaric acid dialdehyde is used as A slimicide in paper manufacturing
Glutaric acid dialdehyde is used as A preservative in cosmetics
A pungent colorless oily liquid, Glutaric acid dialdehyde from our end is used to sterilize medical and dental equipment.
Glutaric acid dialdehyde is also used for industrial water treatment and as a preservative.
The use of Glutaric acid dialdehyde is particularly recommended in the Biosafety Ruls of the National Health Department and in almost all the Reglamentations on the subject in the work.
Glutaric acid dialdehyde is also recommended by almost all the manufacturers of endoscopic instruments, for their disinfection of high level and/or sterilization.
In neutral or slightly alkaline environments, this product develops its peak of efficacy, killing Gram + bacteria, Gram - bacteria, fungus, lipophilic virus, microbacteria, and even bacterial spores.
Moreover, when the product is activated, the medium and the stabilizing and oxidizing additives of it, provides the product longer shelf life to surgical instruments in general, prevents drying and cracking of plastic and rubber materials, as well as the corrosion of the low quality stainless steel materials.
Glutaric acid dialdehyde is a potent antimicrobial/sterilant used to disinfect equipment, surfaces, and laundry in the health care and cosmetology industries.
Cosmetic Uses of Glutaric acid dialdehyde:
preservatives
Crosslinking rigidifies and deactivates many biological functions, so in this way, Glutaric acid dialdehyde solutions are used as biocides and as fixative.
Glutaric acid dialdehyde uses:
-As a disinfectant, Glutaric acid dialdehyde is used to sterilize surgical instruments.
-Glutaric acid dialdehyde is used as Disinfectant for surgical instruments that cannot be heat sterilized
-Glutaric acid dialdehyde is used as A cross-linking and tanning agent
-Glutaric acid dialdehyde is used as A biocide in metalworking fluids and in oil and gas pipelines
Glutaric acid dialdehyde is used for industrial, laboratory, agricultural, medical, and some household purposes, primarily for disinfecting and sterilization of surfaces and equipment.
For example, Glutaric acid dialdehyde is used in oil and gas recovery operations and pipelines, waste water treatment, x-ray processing, embalming fluid, leather tanning, paper industry, in fogging and cleaning of poultry houses, and as a chemical intermediate in the production of various materials.
-Biochemistry:
Glutaric acid dialdehyde is used in biochemistry applications as an amine-reactive homobifunctional crosslinker and fixative.
Glutaric acid dialdehyde kills cells quickly by crosslinking their proteins.
Glutaric acid dialdehyde is usually employed alone or mixed with formaldehyde as the first of two fixative processes to stabilize specimens such as bacteria, plant material, and human cells.
Another application for treatment of proteins with Glutaric acid dialdehyde is the inactivation of bacterial toxins to generate toxoid vaccines, e.g. the pertussis (whooping cough) toxoid component in the Boostrix Tdap vaccine produced by GlaxoSmithKline.
-Material Science:
In material science Glutaric acid dialdehyde application areas vary from polymers to metals and biomaterials.
Glutaric acid dialdehyde commonly used as fixing agent before characterization of biomaterials for microscopy.
Glutaric acid dialdehyde is a powerfull crosslinking agent for many polymers contain primer amine groups.
Crosslinking with Glutaric acid dialdehyde can be used for a polymeric mixture or also can we used as interlinking agent between two different polymeric layers, and an interlinking agent to improve the adhesion force between two polymeric coatings.
Glutaric acid dialdehyde may be used in select goods, such as paint and laundry detergent.
A second fixative procedure uses osmium tetroxide to crosslink and stabilize cell and organelle membrane lipids.
Glutaric acid dialdehyde also used for undersea pipes to protect against corrosion.
-Medical:
Clinical uses:
Glutaric acid dialdehyde is used as a disinfectant and medication.
Glutaric acid dialdehyde is usually applied as a solution, Glutaric acid dialdehyde is used to sterilize surgical instruments and other areas.
Dermatological uses of Glutaric acid dialdehyde:
As a medication Glutaric acid dialdehyde is used to treat plantar warts.
For this purpose, a 10% w/v solution is used.
Glutaric acid dialdehyde dries the skin, facilitating physical removal of the wart.
Glutaric acid dialdehyde is also used in the treatment of hyperhidrosis under the control of dermatologists.
In people who have frequent sweating but do not respond to aluminum chloride.
Glutaric acid dialdehyde solution is an effective agent to treat palmar and plantar hyperhidrosis as an alternative to tannic acid and formaldehyde.
Veterinary uses of Glutaric acid dialdehyde:
Glutaric acid dialdehyde diluted with water is often sold as alternative to carbon dioxide gas injection for aquarium plants.
Glutaric acid dialdehyde is commonly also used by aquarists in low doses as an algaecide.
Glutaric acid dialdehyde is used to disinfect medical and dental equipment.
Glutaric acid dialdehyde is also used for industrial water treatment and as a preservative.
Glutaric acid dialdehyde is used to reduce degradation in cells, tissues, and entire organisms before further experiments like electron microscopy.
Glutaric acid dialdehyde is used to fix specimen before electron microscopy where Glutaric acid dialdehyde is employed alone or mixed with polymethanal (paraformaldehyde) as the first of 2 fixations followed by osmium tetroxide.
Glutaric acid dialdehyde is used as an amine cross-linker.
Glutaric acid dialdehyde is used in SDS-PAGE to fix/crosslink proteins and peptides prior to staining.
Gels are treated with a 5% solution for ~30 min, after which it must be thoroughly washed to remove the yellow stain brought about by reacting with free Tris.
Alternatively, gels can be washed before fixation.
PHYSICAL and CHEMICAL PROPERTIES of Glutaric acid dialdehyde:
Physical state: clear, liquid
Color: colorless
Odor: No data available
Melting point/freezing point:
Melting point/range: -6 °C
Initial boiling point and boiling range: 101 °C at 1.013 hPa
Flammability (solid, gas): No data available
Glutaric acid dialdehyde is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.
At room temperature Glutaric acid dialdehyde is a pungent colourless oily liquid and is mainly available as an aqueous solution of 50% concentration.
Glutaric acid dialdehyde solution of 0.1% to 1.0% concentration may be used as a biocide for system disinfection and as a preservative for long term storage.
Glutaric acid dialdehyde is a sterilant, killing endospores in addition to many microorganisms and viruses.
Glutaric acid dialdehyde is also used for industrial water treatment and as a chemical preservative.
Glutaric acid dialdehyde is a colorless liquid with a pungent odor used to sterilize medical and dental equipment.
Glutaric acid dialdehyde is used as a tissue fixative in electron microscopy.
Glutaric acid dialdehyde is employed as an embalming fluid, is a component of leather tanning solutions, and occurs as an intermediate in the production of certain industrial chemicals.
Glutaric acid dialdehyde is also used for industrial water treatment and as a chemical preservative.
Glutaric acid dialdehyde is frequently used in biochemistry applications as an amine-reactive homobifunctional crosslinker.
The oligomeric state of proteins can be examined through this application.
Monomeric Glutaric acid dialdehyde can polymerize by aldol condensation reaction yielding alpha,beta-unsaturated poly-glutaraldehyde.
This reaction usually occurs at alkaline pH values.
A Glutaric acid dialdehyde solution of 0.1% to 1.0% concentration may be used for system disinfection and as a preservative for long term storage.
Glutaric acid dialdehyde is used in biological electron microscopy as a fixative.
Glutaric acid dialdehyde kills cells quickly by crosslinking their proteins and is usually employed alone or mixed with formaldehyde as the first of two fixative processes to stabilize specimens such as bacteria, plant material, and human cells.
A second fixative procedure uses osmium tetroxide to crosslink and stabilise cell and organelle membrane lipids.
Fixation is usually followed by dehydration of the tissue in ethanol or acetone, followed by embedment in an epoxy resin or acrylic resin.
Glutaric acid dialdehyde is also used in SDS-PAGE to fix proteins and peptides prior to staining.
Typically, a gel is treated with a 5% solution for approximately one half hour, after which it must be thoroughly washed to remove the yellow stain brought about by reacting with free tris.
Glutaric acid dialdehyde is a disinfectant, which is rapidly effective against vegetative forms of Gram-positiveand Gram-negative bacteria.
Glutaric acid dialdehyde is used in hospitals and medical and dental offices in solutions for cold sterilization and automatic processing of x-rays.
It is claimed that Glutaric acid dialdehyde provides a bioavailable source of carbon for higher plants that is not available to algae.
Glutaric acid dialdehyde is used for cross-linking proteins and polyhydroxy materials.
Also Glutaric acid dialdehyde is used as a fixative for tissues and as an amine-reactive homobifunctional crosslinker.
Glutaric acid dialdehyde is also used in coupling reaction of biotin hydrazides to nucleic acids which is useful for conjugating fluorescent hydrazides and hydroxylamines to DNA and for stabilization ofproteins on agarose beads,activation of polystyrene and glass, for immobilization of antibodies and antigens.
Glutaric acid dialdehyde is used as a tissue fixative in histology and microscopy, chemical intermediate, embalming fluid, biocide (cosmetics, water treatment, oilfield, and fish farming applications), disinfectant, cross-linking agent, leather tanning agent, gelatine hardening agent, and keratolytic.
Glutaric acid dialdehyde is used as an antimicrobial agent in agricultural, food handling, commercial, industrial, residential, public, and medical environments.
Glutaric acid dialdehyde is used as a fungicide, also used for leather tanning.
Also Glutaric acid dialdehyde is used as materials preservative (cleansers, adhesives, paper, water based coatings, latex paints, inks, dyes, concrete admixtures, and reverse osmosis membranes) and in industrial processes and water systems treatment (recirculating and waste-water water systems, drilling muds, oil and gas storage systems, paper mills, and metalworking fluids).
The largest single use of Glutaric acid dialdehyde is as an antimicrobial, bactericide, fungicide and a virucide.
Glutaric acid dialdehyde is used to sterilize hospital and veterinary equipment, and to disinfect surfaces in hospitals, veterinary hospitals, nursing homes, and food processing plants.
Glutaric acid dialdehyde is used to prevent bacterial growth in water supplies for washing air, cooler systems, logging ponds, and pulp and paper water systems.
Smaller uses are as an embalming fluid, as a fixative for tissues, for film processing and leather tanning.
Glutaric acid dialdehyde is used As bactericide, disinfector, tanning agent, widely used in petroleum development, leather treatment, food, plastics, coatings etc.
Glutaric acid dialdehyde is used as a disinfectant, as an intermediate in classical synthesis of pseudopelleterine, as a tanning agent in leather, and in the sterilization of endoscopic instruments, dental and barber equipment, thermometers, rubber or plastic equipment which cannot be heat sterilized.
Glutaric acid dialdehyde is used also as embalming fluid, in electron microscopy. Hardener for photographic gelatin.
Glutaric acid dialdehyde, Pharmacological agent used for hyperhidrosis and antifungal purposes and for treatment of warts and some bullous diseases as well as herpes infections.
Glutaric acid dialdehyde contains 5% sorbitan sesquioleate as emulsifier.
Glutaric acid dialdehyde is used as an antimicrobial agent in sugar mills and as a fixing agent in the immobilisation of glucose isomerase enzyme preparations for use in the manufacture of high fructose corn syrup.
Glutaric acid dialdehyde is also used for industrial water treatment and as a chemical preservative.
Glutaric acid dialdehyde is used as a disinfectant, it is used to sterilize surgical instruments.
USES AND APPLICATIONS OF Glutaric acid dialdehyde:
Glutaric acid dialdehyde is used as a disinfectant in animal housing
Glutaric acid dialdehyde is used as a tissue fixative in histology and pathology labs
Glutaric acid dialdehyde is used as a hardening agent in the development of X-rays
Glutaric acid dialdehyde is used as in embalming solutions
Glutaric acid dialdehyde is used as in the preparation of grafts and bioprostheses
Glutaric acid dialdehyde is used as in various clinical applications
Glutaric acid dialdehyde is a polymerized isomer of glutaraldehyde known as polycycloglutaracetal used as a fertilizer for aquatic plants.
It is claimed that Glutaric acid dialdehyde provides a bioavailable source of carbon for higher plants that is not available to algae.
Though not marketed as such due to federal regulations, the biocidal effect of glutaraldehyde kills most algae at concentrations of 0.5 - 5.0 ppm.
These levels are not harmful to most aquatic fauna and flora.
Adverse reactions have been observed by some aquarists at these concentrations in some aquatic mosses, liverworts, and vascular plants.
Glutaric acid dialdehyde is also used for industrial water treatment and as a chemical preservative.
Glutaric acid dialdehyde is used as a tissue fixative in electron microscopy.
Glutaric acid dialdehyde is used as bactericide, disinfector, tanning agent, widely used in petroleum development, leather treatment, food, plastics, coatings etc.
Glutaric acid dialdehyde is also employed as an embalming fluid, is a component of leather tanning solutions, and occurs as an intermediate in the production of certain industrial chemicals.
Crosslinking rigidifies and deactivates many biological functions, so in this way, Glutaric acid dialdehyde solutions are used as biocides and as fixative.
Glutaric acid dialdehyde is frequently used in biochemistry applications as an amine-reactive homobifunctional crosslinker.
The oligomeric state of proteins can be examined through this application.
A pungent colorless oily liquid, Glutaric acid dialdehyde is used to disinfect medical and dental equipment.
Glutaric acid dialdehyde is commonly also used by aquarists in low doses as an algaecide.
Glutaric acid dialdehyde is applied as a disinfectant for heat-sensitive medical and dental equipment.
Glutaric acid dialdehyde’s biocidal properties are also utilized for industrial water treatment, hydraulic fracking, and as a topical wart treatment.
Glutaric acid dialdehyde is a preferred fixing agent for biological tissues, since Glutaric acid dialdehyde is nonvolatile, and is widely used for leather tanning, embalming, creation of toxoid vaccines, or preparing cell specimens for electron microscopy.
Glutaric acid dialdehyde is also used to fix certain enzymes during the production of high fructose corn syrup.
Glutaric acid dialdehyde is widely used in embalming; in the manufacture of adhesives, sealants, and electrical products; as a cross-linking agent for proteins and polyhydroxy compounds; in microcapsules containing flavoring agents; and as a tissue fixative in electron microscopy, the paper and leather tanning industries, and x-ray film developing solutions.
Glutaric acid dialdehyde is also used as a sterilizing agent for plastics, rubber, thermometers, lenses, and other surgical, dental, and hospital equipment.
Glutaric acid dialdehyde is an effective sporicidal agent, requiring about 3 h for an almost complete kill of spores as well as gram-negative and gram-positive bacteria, fungi, and viruses.
Glutaric acid dialdehyde has been used in surgical procedures including colonic anastomoses and dental pulpotomies.
Glutaric acid dialdehyde solutions (5-25%) are used clinically to treat skin disorders, including warts, hyperhidrosis (excessive sweating of the hands or soles of the feet), herpes simplex, and herpes zoster, and in the preparation of grafts and bioprostheses.
The preservative and antimicrobial properties of Glutaric acid dialdehyde have found broad application in cosmetic, toiletry, and chemical specialty products because of glutaraldehyde's water solubility and usefulness in systems containing secondary or tertiary amines, quaternary ammonium compounds, or protonated amines.
Glutaric acid dialdehyde solutions often are used as cell and tissue fixatives in biochemical experiments during space-shuttle flights.
Glutaric acid dialdehyde diluted with water is often sold as alternative to carbon dioxide gas injection for aquarium plants.
A pungent colorless oily liquid, Glutaric acid dialdehyde is used to sterilise medical and dental equipment.
Glutaric acid dialdehyde, 2%, solution is used in biochemistry applications as an amine-reactive homobifunctional crosslinker and fixative prior to SDS-PAGE, staining, or electron microscopy.
Glutaric acid dialdehyde is a disinfectant, medication, preservative, and fixative.
Application Areas of Glutaric acid dialdehyde:
-Disinfectant Chemical
-Water Treatment Chemical
-Pharmaceutical Chemical
-Biocides
Glutaric acid dialdehyde is widely used for oil production, medical care, bio-chemical, leather treatment, tanning agents, protein cross-linking agent; in the preparation of heterocyclic compounds; also used for plastics, adhesives, fuels, perfumes, textile, paper making, printing; corrosion prevention of instruments and cosmetics etc.
FEATURES of Glutaric acid dialdehyde:
-Aldehyde groups are hydrated
-Pungent and oily liquid
-Lasts long
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity:
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: soluble
Partition coefficient: n-octanol/water: No data available
Vapor pressure: 20 hPa at 20 °C
Density: 1,106 g/cm3
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not classified as explosive.
Oxidizing properties: none
Other safety information: No data available
FIRST AID MEASURES of Glutaric acid dialdehyde:
-Description of first-aid measures:
-General advice:
Show this material safety data sheet to the doctor in attendance.
-If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
-In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
-In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
-If swallowed:
After swallowing:
Make victim drink water (two glasses at most), avoid vomiting (risk of perforation).
Call a physician immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available
ACCIDENTAL RELEASE MEASURES of Glutaric acid dialdehyde:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up carefully with liquid-absorbent material.
Dispose of properly.
FIRE FIGHTING MEASURES of Glutaric acid dialdehyde:
-Extinguishing media:
-Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
-Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of Glutaric acid dialdehyde:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
-Eye/face protection:
Use Tightly fitting safety goggles.
-Skin protection:
Handle with gloves.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 30 min
-Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of Glutaric acid dialdehyde:
-Precautions for safe handling:
-Advice on safe handling:
Work under hood.
-Hygiene measures:
Immediately change contaminated clothing.
Wash hands and face after working with substance.
STABILITY and REACTIVITY of Glutaric acid dialdehyde:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available
SYNONYMS:
Glutaraldehyde
Glutardialdehyde
Glutaric acid dialdehyde
Glutaric acid dialdehyde
Glutaric acid dialdehyde
1,5-Pentanedial
glutaraldehyde
Pentanedial
Glutaral
Glutaric acid dialdehyde
Cidex
Glutardialdehyde
1,5-Pentanedial
Sonacide
Glutaric acid dialdehyde
Pentane-1,5-dial
Glutaraldehyd
Glutaric acid dialdehyde
Glutaralum
Glutarol
Ucarcide
Aldesan
Alhydex
Hospex
1,3-Diformylpropane
Gluteraldehyde
1,5-Pentanedione
Aldesen
Novaruca
Sporicidin
Aldehyd glutarowy
NCI-C55425
Glutaclean
Sterihyde
Aqucar
Veruca-sep
Sterihyde L
Relugan GT
Relugan GTW
component of Cidex
Glutarex 28
NSC 13392
Sonacide (TN)
Cidex 7
Ucarcide 250
UNII-T3C89M417N
Relugan GT 50
Sterihyde L (TN)
Coldcide-25 microbiocide
Glutaral (JAN/USP/INN)
Potentiated acid glutaraldehyde
CHEBI:64276
T3C89M417N
1, 5-Pentanedial
NSC-13392
NCGC00091110-01
DSSTox_CID_5355
DSSTox_RID_77761
DSSTox_GSID_25355
Glutaraldehyde Solution, 25%
Caswell No. 468
Glutaraldehyde solution
1,3-Diformyl propane
Diswart
Gludesin
Glutarol-1,5-pentanedial
Polyglutaraldehyde
Poly(glutaraldehyde)
CCRIS 3800
HSDB 949
EPA Pesticide Chemical Code 043901
BRN 0605390
pentandial
Dioxopentane
Glutural
Ucarset
Verucasep
Glutaraldehyde solution, for electron microscopy, ~25% in H2O
Virsal
Glutaral(usan)
glutaric dihydride
GLUTARALDEHYDE, 25% SOLN
Glutaral concentrate
Bactron K31
Ucarcide 225
Glutaraldehyde solution (50% or less)
Glutaraldehyde solution, 25% in water
Pentanedial, homopolymer
pentane-1,5-dialdehyde
Glutaral, INN, USAN
Protectol GDA, GT 50
SCHEMBL836
WLN: VH3VH
4-01-00-03659 (Beilstein Handbook Reference)
BIDD:ER0299
Glutaraldehyde Solution, 50%
CHEMBL1235482
DTXSID6025355
AMY3308
Bio1_000462
Bio1_000951
Bio1_001440
NSC13392
STR01121
ZINC1729593
Tox21_111083
Tox21_201742
Tox21_303295
STL281872
AKOS008967285
DB03266
Glutaric acid dialdehyde, 25%sol. In water
Glutaric acid dialdehyde, 25% sol. in water
NCGC00091110-02
NCGC00091110-03
NCGC00257231-01
NCGC00259291-01
Glutaraldehyde solution, 25 wt. % in H2O
Glutaraldehyde solution, 50 wt. % in H2O
FT-0626730
G0067
G0068
EN300-18037
D01120
Glutaraldehyde solution, for synthesis, 25.0%
Glutaraldehyde solution, Grade II, 25% in H2O
A802339
Q416475
Glutaraldehyde solution, for in vitro diagnostic use
Q-201162
Glutaric acid dialdehyde solution, 50 wt. % in H2O, FCC
F2191-0161
Glutaraldehyde solution, SAJ first grade, 20.0-26.0%
Glutaraldehyde solution, technical, ~25% in H2O (2.6 M)
Glutaraldehyde solution, technical, ~50% in H2O (5.6 M)
Glutaraldehyde solution, 1.2 % (w/v) glutaraldehyde in H2O
Glutaraldehyde solution, for electron microscopy, ~50% in H2O
Glutaraldehyde solution, for electron microscopy, ~8% in H2O
NCI-C55425; Pentanedial
Potentiated acid glutaraldehyde
Sonacide
EPA Pesticide Code: 043901
Glutaraldehyde solution, Glutaric acid dialdehyde solution
Glutaraldehyde solution, 50% in H2O, suitable for photographic applications
Aldesan
Alhydex
Cidex
Cudex
1,3-diformylpropane
Dioxopentan
Glutamic dialdehyde
Glutaral
Glutaralum
Glutardialdehyde
Glutaric acid dialdehyde
Glutaric acid dialdehyde
Glutohyde; Hospex