Iodopropynyl Butyl Carbamate (IPBC)


IPBC20 
IPBC 30
IPBC 40
IPBC Solid Powder


Chemical name: 3-iodo-2-propynyl butyl carbomate

Chemical characterization
3-iodo-2-propynylbutylcarbamate (in a Glycol and Alcohol)

EC / List no.: 259-627-5
CAS no.: 55406-53-6


3-Iodo-2-propynylbutyl carbamate is broad spectrum preservative and dry film fungicide. 
3-Iodo-2-propynylbutyl carbamate is used in interior and exterior paints, wood protective stains, paper coatings, plastic coatings and inks. 
3-Iodo-2-propynylbutyl carbamate exhibits low viscosity, easy pumping and no settling of solids. 
3-Iodo-2-propynylbutyl carbamate offers low freezing point temperature. 
3-Iodo-2-propynylbutyl carbamate possesses very good dry film fungal protection.

Iodopropynyl Butyl Carbamate (IPBC) is a preservative used globally in the paints & coatings, wood preservatives, personal care, and cosmetics industries. 
IPBC is a member of the carbamate family of biocides.
IPBC was invented in the 1970s and has a long history of effective use as an antifungal technology.

IPBC was initially developed for use in the paint & coatings industry as a dry-film preservative to protect interior and exterior coatings from mold, mildew, and fungal growth, while also offering cost performance and sustainability benefits. 
IPBC exhibits efficacy against a broad spectrum of fungal species, typically at very low use levels. 
IPBC today is incorporated into a wide variety of interior and exterior paint formulations around the world.

Use is restricted in some countries due to its toxicity, especially acute inhalation toxicity. 
IPBC is also becoming recognized as a contact allergen.

Uses
IPBC is an effective fungicide at very low concentrations in cosmetic and other products, and has shown very low sensitivity in humans tested with this preservative. 
IPBC was approved in 1996 for use up to 0.1% concentrations in topical products and cosmetics. 
However, this preservative is mostly found in cosmetics at about one-eighth that level. 
IPBC Toxicity and Safety Tests show it to be generally safe: When used properly in leave-on skin products, IPBC is extremely safe. 
Previous to being approved for cosmetic use in 1996, extensive safety and toxicity tests were conducted on IPBC and their results were gathered along with earlier studies in a report of the Safety Assessment of IPBC by the Cosmetic Ingredient Review. 
This final report found IPBC to be a non-carcinogen with no genotoxicity and in reproductive and developmental toxicity studies using rats and mice, IPBC had no significant effect on fertility, reproductive performance, or on the incidence of fetal malformation.

Toxicity
The study, "Final Report on the Safety Assessment of Iodopropynyl Butylcarbamate", discusses the results of 32 studies between 1990 and 1994 in 3,582 subjects using skin application of IPBC at relevant concentrations. 
All 32 studies showed no evidence of contact sensitization compared to placebo controls, with the report stating "With each test formulation, a few panelists had erythema, edema, and/or a papular response, but overall, the results were negative." 
In addition, the study mentions two skin sensitivity studies on 183 children ages 3 – 12 yrs which showed no adverse effects as well as no significant irritation from IPBC.

Since the early safety report, there have been a few reports of human skin sensitivity to IPBC in individual patients – all of which showed complete recovery after discontinuance of use of any product containing the IPBC which was presumably an allergen for these patients.

Post-1996 tests of human sensitivity to IPBC have all shown quite low sensitivity, having overall reported human skin testing (patch test) on 53,774 subjects with only 491 of those subjects showing any reaction (0.8%) to IPBC. 
In every study, positive patch test reactions occurred in less than 1% of subjects tested in all but one study. 
This is a very low reaction rate, but it is not zero, and the industry reports this low rate of reaction even though in the largest study of 25,435 subjects over 69% of the reactions were either weak or doubtful.

These combined studies showing prevalence of reaction below 1% means that IPBC at this time does not have the reaction rates necessary to be included as an allergen in standard allergy series. 
But, it remains under close monitoring as it is a relatively new preservative for cosmetic products and will presumably increase in usage.

Most human patch tests performed before 2004 were with 0.1% IPBC solutions, i.e. 10 times the concentration used in many cosmetic products. Some used 0.5% IPBC. 
In 2004, it was suggested that a better concentration for tests of this substance would be 0.2% and this has contributed to the diagnosis of more sensitizations to this substance.
One study showed significantly increased sensitivity between 2005 and 2010 using 0.5% IPBC in patch tests [Warshaw et al., 2013b].


3-iodo-2-propynyl butylcarbamate
3-iodo-2-propynyl butylcarbamate
3-iodo-2-propynyl butylcarbamate; 3-iodoprop-2-yn-1-yl butylcarbamate
3-Iodo-2-propynylbutylcarbamate

3-iodo-2-propynylbutylcarbamate (IPBC)
3-iodoprop-2-yn-1-yl butylcarbamate
Butyl-3-iodo-2-propynylcarbamate

Carbamic acid, butyl-3-iodo-2-propynyl ester
Carbamic acid, N-butyl-, 3-iodo-2-propyn-1-yl ester
Iodopropynyl butylcarbamate
Troysan KK-108A
Troysan polyphase anti-mildew
Woodlife


IPBC is a fungicide/antimicrobial used as a preservative in paint, adhesives, emulsions, metal cutting fluids, oil recovery drilling mud/packer fluids, plastics, textiles, inks, paper coatings, and wood products. 
IPBC is also used in residential settings as a wood preservative stain to combat wood rot/decay, and as a preservative in paints. 
IPBC is also applied to heating, ventilation, and air conditioning (HVAC) ducts and equipment to control mold and fungi 

3-Iodo-2-propynyl N-butylcarbamate is also referred to as iodopropynyl butylcarbamate (IPBC). 
IPBC is widely used as antifungal[1] and anti-microbial agent.
IPBC can be encapsulated in polystrene/polycaprolactone blend in the form microspheres. 
The microspheres were tested for invitro antifouling activity.


Translated names
3-Iod-2-propinyl butylcarbamat (IPBC) (de)
3-iod-2-propynyl butylkarbamat (no)
3-iod-2-propynylbutylcarbamat (IPBC) (da)
3-iodo-2-propinilbutilcarbamat (IPBC) (ro)
3-iodo-2-propynylbutylcarbamate (IPBC) (mt)
3-iodo-2-propynylbutylcarbamate (IPBC) (no)
3-iodprop-2-yn-1-yl butylkarbamat (no)
3-jod-2-propinilbutilkarbamatas (IPBC) (lt)
3-Jod-2-propinilbutilkarbamāts (IPBC) (lv)
3-jodi-2-propynyylibutyylikarbamaatti (IPBC) (fi)
3-jodo-2-propinil butilkarbamat (IPBC) (sl)
3-jodo-2-propinilbutilkarbamat (IPBC) (hr)
3-jodo-2-propynylbutylkarbamat (IPBC) (sv)
3-jodo-2-propynylo butylokarbaminian (IPBC) (pl)
3-jodo-2-propünüülbutüülkarbamaat (IPBC) (et)
3-jodprop-2-yn-1-yl-N-butylkarbamát (IPBC) (cs)
3-Jood-2-propynylbutylcarbamaat (IPBC) (nl)
3-jód-2-propinil-butilkarbamát (IPBC) (hu)
3-jódprop-2-inyl-butylkarbamát (IPBC) (sk)
3-йодо-2-пропинилбутилкарбамат (IPBC) (bg)
Butilcarbamato de 3-iodo-2-propinilo (IPBC) (pt)
Butilcarbamato de 3-yodo-2-propinilo (IPBC) (es)
Butilcarbammato di 3-iodo-2-propinile (IPBC) (it)
butylcarbamate de 3-iodo-2-propynyle; butylcarbamate de 3-iodoprop-2-yn-1-yle (fr)
Carbamate de 3-iodo-2-propynylbutyle (IPBC) (fr)
Βουτυλοκαρβαμιδικό 3-ιωδο-2-προπυνύλιο (IPBC) (el)

CAS names
Carbamic acid, N-butyl-, 3-iodo-2-propyn-1-yl ester
IUPAC names
3-Iodo-2-propinylbutyl carbamate
3-Iodo-2-propynyl butyl carbamate
3-iodo-2-propynyl butyl carbamate

3-IODO-2-PROPYNYL BUTYLCARBAMATE

3-Iodo-2-propynyl butylcarbamate
3-iodo-2-propynyl butylcarbamate
3-iodo-2-propynyl butylcarbamate (part of prep.)
3-iodo-2-propynyl butylcarbamate; 3-iodoprop-2-yn-1-yl butylcarbamate
3-Iodo-2-propynyl N-Butylcarbamate
3-Iodo-2-propynyl N-butylcarbamate
3-IODO-2-PROPYNYL-N-BUTYLCARBAMATE
3-iodoprop-2-yn-1-yl butylcarbamate
3-iodoprop-2-yn-1-yl N-butylcarbamate
3-iodoprop-2-ynyl N butylcarbamate
3-iodoprop-2-ynyl N-butylcarbamate
Carbamic acid, N-butyl-, 3-iodo-2-propyn-1-yl ester

Iodopropynylbutylcarbamate (IPBC)
Registration dossier
IPBC, Omacide IPBC
Registration dossier


Reactivity Profile
Iodopropynyl butylcarbamate is a carbamate ester. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.

Contact allergens
Iodopropynyl butylcarbamate (IPBC) is a broad-spec- trum preservative used for years because of its wide field of application, in polymer emulsions and pigment dispersions such as water-based paints and adhesives, cements and inks, as a wood preservative, in metal- working fluids, household products, and cosmetics. Allergic contact dermatitis to IPBC was reported due to cosmetics, from sanitary wipes, and in metalworkers.

Contact allergens
Iodopropynyl butylcarbamate has produced slight irritation in rabbits. However, it was not found to be either a skin sensitizer or a photo sensitizer in guinea pigs. Cosmetic formulations containing up to 0.125% of iodopropynyl butylcarbamate produce no significant irritation or sensitization reactions in human repeated insult patch tests. Iodopropynyl butylcarbamate did not cause crosssensitization reactions in patients who had demonstrated sensitivity to related dithiocarbamate compounds. In the European Union, it is approved as a preservative up to 0.05% and is not to be used in oral hygiene or lip care products. If the concentration exceeds 0.02% in leave-on products, a warning label must indicate that the product contains iodine.

Clinical Use
Iodopropynyl butylcarbamate (3-iodo-2-propynyl-butylcarbamate) is a highly effective fungicide as well as a bactericide. It was first used in the 1970s as a film fungicide for paint and then as a wood preservative, where final use concentration up to 4% was permitted. For paint and coatings usually no more than 0.5% iodopropynyl butylcarbamate is used. For metalworking fluids, adhesives, textiles, and paper, concentrations between 0.1%and 0.2% are common. The Cosmetic Ingredient Review Expert Panel concluded that iodopropynyl butylcarbamate is safe as a cosmetic ingredient in concentrations less than or equal to 0.1%and that it should not be used in products intended to be aerosolized. By 1996, iodopropynyl butylcarbamate was used in 122 formulations reported to the United States Food and Drug Administration. Iodopropynyl butylcarbamate is found in a wide variety of occupational and consumer products, including shampoos, lotions, powders, makeup, baby products, paints, coatings, metalworking fluids, household products, cooling water, building materials, and contact lenses. It is an irritant, although at low concentrations few problems have been reported.


55406-53-6

3-iodoprop-2-yn-1-yl butylcarbamate

Iodopropynyl butylcarbamate

Iodocarb

3-Iodo-2-propynyl butylcarbamate

Ipbc

Woodlife

1-Iodoprop-1-yn-3-yl N-n-butylcarbamate

Carbamic acid, butyl-, 3-iodo-2-propynyl ester

Troysan KK-108A

3-iodoprop-2-ynyl N-butylcarbamate

Troysan polyphase anti-mildew

3-Iodo-2-propynyl-N-butylcarbamate

UNII-603P14DHEB

Butyl-3-iodo-2-propynylcarbamate

603P14DHEB

CHEBI:83279

3-iodoprop-2-ynyl butylcarbamate

Carbamic acid, N-butyl-, 3-iodo-2-propyn-1-yl ester

DSSTox_CID_8038

DSSTox_RID_78646

DSSTox_GSID_28038

Caswell No. 501A

CAS-55406-53-6

HSDB 7314

3-Iodo-2-propynyl butyl carbamate

EINECS 259-627-5

EPA Pesticide Chemical Code 107801

BRN 2248232

iodocarbe

Carbamic acid, butyl-3-iodo-2-propynyl ester

ACMC-209uq3

SCHEMBL114369

CHEMBL1893913

DTXSID0028038

KS-00000LXO

ZINC1850357

3-Iodo-2-propynyl butylcarbamate #

Tox21_201864

Tox21_301117

ANW-44089

MFCD00072438

AKOS015905567

GS-3240

3-iodo-2-propyn-1-yl N-butylcarbamate

3-iodoprop-2-yn-1-yl N-butylcarbamate

Iodocarb 100 microg/mL in Acetonitrile

NCGC00164376-01

NCGC00164376-02

NCGC00164376-03

NCGC00164376-04

NCGC00164376-05

NCGC00255017-01

NCGC00259413-01

AK-49902

3-Iodo-2-propynyl N-butylcarbamate, 97%

3-IODO-2-PROPYNYL BUTYL CARBBAMATE

FT-0615885

I0666

N-Butylcarbamic Acid 3-Iodo-2-propynyl Ester

06I536

M-7688

Q2928998

W-105563


Iodopropynyl butylcarbamate or IPBC is a preservative used in wet wipes, paint, primers, coating and cosmetics to prevent bacteria and fungi’s in the products. It has been approved by the FDA for use as a component of adhesive that may safely be used in articles intended for use in packing and holding food. IPBC was developed in the 1970´s for industrial use in the wood industry as a preservative for paint and coating and in 1996 it was approved for cosmetics. In the EU, IPBC is not allowed in leave on products to small children (≤3 years).

The use of IPBC in cosmetics in the European Union is subject to the restrictions described in Annex VI, Part I of the Cosmetics Directive. Because of the iodine content the concentration allowed to use in cosmetic products is regulated to:

Rinse off 0,02 %
Leave on 0,01 %
Deodorants/antiperspirants 0,0075 %
 

So, what is the problem?

IPBC was for a long time considered to have a low allergenic potential. However because of the extended use in many products and the fact that it is a small molecule that can penetrate the skin, it can cause contact dermatitis in especially leave on products from specific product groups. Because of the wide use of IPBC a big populations study was done in Denmark from 2000-2011, where all patients who had a patch test were included in the study.

9755 patients were tested and 54 cases of allergy to IPBC was found.

Allergy to IPBC was significant more prevalent among men and patients with occupational dermatitis. The study concluded that IPBC continues to be among the less frequent allergens, and furthermore that IPBC allergy is typically related to men over 40 years old working in the wood industry and with hand eczema.

To conclude: In Denmark – and we believe this may be extrapolated to the rest of the EU – IPBC allergy is related to the male sex, age > 40 years, hand eczema, and occupational exposure. Physicians should be encouraged to investigate possible occupational exposure if IPBC sensitization is detected.  

 

What the experts say about IPBC

The safety of IPBC has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel twice. The first assessment was made in 1998 where the CIR Expert Panel concluded that IPBC was safe as cosmetic ingredient at concentrations ≤0,1 %, but it should not be used in aerosol products, because of a negative effect in lungs.

In 2016 new studies were made and a re-assessment on IPBC was made. CIR evaluated the updated scientific data and according to the panel there is a low degree of sensitization observed in some studies and mild dermal irritation potential of IPBC at concentrations of 0.5% and above. IPBC was negative in tests for mutagenicity, carcinogenicity and reproductive and developmental toxicity. The CIR concluded that IPBC was safe as a cosmetic ingredient at concentrations less than or equal to 0.1%, but IPBC should not be used in products intended to be aerosolized.

The Scientific Committee on cosmetic product intended for consumers (SCCNFP) is of the opinion that IPBC is safe for use in cosmetic products as a preservative at a maximum concentration of 0,05 %. The SCCNFP proposes the following further restriction or condition for its use in cosmetic products: the substance should not be used in oral hygiene and lip products. Leave on products containing more than 0,02 % IPBC must be labelled “contain iodine”.  

 

AllergyCertified

AllergyCertified make an allergy risk assessment for all ingredients used in a certified product. The assessment of IPBC shows that IPBC can be allowed in mascara since both the exposure and the concentrations (≤ 0,01 %) used in mascara is so low that it is safe to use. But in other products with a bigger exposure than mascara this preservative is not allowed because of the risk of getting an allergic reaction.  


3-Iodo-2-propynylbutyl carbamate
Concentration : 30 % ( You can find datas of 20 % and 40 % IPBC versions also below )
CAS number : 55406-53-6
EINECS number : 259-627-5

Iodopropynyl butylcarbamate (IPBC) is a highly effective fungicide and bactericide. 
Iodopropynyl butylcarbamate (IPBC) is used as a preservative for wood and paints as well as in cosmetic formulations and various consumer products.


This chemical can be identified by different names, including:
3-Iodo-2-propynyl butyl carbamate, Biodocarb C 450, Butyl-3-iodo-2-propynylcarbamate, Carbamic acid,butyl-3-iodo-2-propynyl ester, Lodopropynyl butylcarbamate, Troysan Polyphase


IPBC is used for the formulation of aqueous wood preservatives, anti-blue-stain agents, primers and wood stains. 
IPBC is used for the formulation of other water-based fungicidal and algaecidal coatings. 
IPBC is prefered as a fungicide in adhesives, cutting oils, inks, plastics, textiles, canvas and cordage.
IPBC is particularly effective against blue-staining fungi and moulds.


Key features
 effective fungicide for a wide range of industrial applications
 broad spectrum activity especially effective against yeasts and moulds
 free from formaldehyde, formaldehyde releasers, phenolics, heavy metals
 good safety profile and handling characteristics
 cost effective fungicide, low use levels
 good compatibility with other raw materials
 effective over pH range 4 – 9

Characteristic properties
 colourless liquid
 soluble in glycols and surfactants
 miscible in oil and water
Our IPBC meets the highest purity requirements.
IPBC prevents microbial deterioration of products and resulting consequences such as:
 phase separation  changes in viscosity
 odour build-up  build-up of health threatening toxins 

Applications
20 % IPBC 20 is highly suitable for the preservation of a wide variety of industrial, cosmetic and toiletry products due to its high activity and acceptable pH and temperature stability.
It shows highest efficacy and stability in a wide pH range of pH 4 - 9.
Experience shows that compatibility with most products and raw materials is excellent, although compatibility testing is recommended for special formulations.

Application areas
 paints
 adhesives
 metal working fluids
 household products
 wood and timber
 sealants and caulks
 shampoos and conditioners
 sun products

Ecological effects (IPBC)
 Fish (trout) LC50 (96h) = 0.33 mg/L (20 % IPBC 20 )
 Daphnia EC50 (48h) = 0.8 mg/L (20 % IPBC 20 )
 Algae EC50 (96h) = 0.265 mg/L (20 % IPBC 20 )

IPBC is rapidly degraded in soil and surface waters, and it has a low bioaccumulation potential.
Toxicological effects (IPBC)
 Oral LD50 (rat): 1500 - 2500 mg/kg (20 % IPBC 20 )
 Inhalation LC50 (rat): 3.4 - 3.8 mg per litre (20 % IPBC 20 )
 Skin irritation: non irritant
 Eye irritation: IPBC is a severe eye irritant (reversible)
 Sensitization: IPBC can cause sensitization

IPBC is non carcinogenic and there is no evidence of genotoxicity in in vitro and in vivo studies.


• Butyl-3-iodo-2-propynylcarbamate
• Carbamic acid, butyl-3-iodo-2-propynyl ester
• Iodopropynyl butylcarbamate
• 3-Iodo-2-propynyl butylcarbamate
• EPA Pesticide Chemical Code 107801
• BRN 2248232
• Caswell No. 501A
• EINECS 259-627-5
• HSDB 7314
• 3-Iodo-2-propynyl butyl carbamate


This may not be a complete list as manufacturers introduce and delete chemicals from their product line

Description; 
 IPBC 30 is a 30% active IPBC clear glycolic fungicide,  IPBC 30 has been developed for fungal dry film protection of water based coatings. 
 IPBC 30 can also be used for wet state, in-can fungal protection. 
 IPBC 30 is effective against a wide range of fungal and yeast species and exhibits some activity against gram negative and gram positive bacteria. 
Dry –film degradation in paints and decorative coatings can be avoided by using the correct dry-film fungicides at the most cost effective use level. 
Ideal dry-film properties achieved by  IPBC3 30 include: 
• High activity against a broad range of fungi and algae 
• Excellent activity at relatively low use concentrations 
• Carbendazim free 
• pH stable 
• UV stable 
• Low water solubility 
• Approved under the Biocidal Products Directive 
• Cost effective protection 

Applications; 
 IPBC 30 is recommended for protection of a wide range of coating applications including water based decorative paints, wood stains and colours. 
 IPBC 30 can also be used in solvent based applications. 
Increased antifungal activity can also be achieved by using  IPBC 30 for in-can use in adhesives grouts and sealants. 
 IPBC 30 is effective against a wide range of spoilage organisms effective over a wide pH range.  
IPBC 30 should not be used in products heated above 400 C. 

Use level; 
 IPBC 30 should be evaluated in finished products at levels between 0.50% and 2.0% for dry film applications. 
The level of protection will depend on many factors including the end destination of coating, relative humidity, sun strength and others and can be determined by evaluation by our team of microbiologists at the ATAMAN CHEMICALS Microbiology facility. 
For in-can antifungal activity  IPBC 30 should be evaluated between 0.10% and 0.30%.

Microbiological data;
Even though  IPBC 30 is designed for dry-film applications it also exhibits activity against a wide range of bacteria, fungi and yeast. 
This can be demonstrated by the following MIC data.

MIC Levels Organism MIC (ppm)

Bacteria
Pseudomonas aeruginosa >1500
Proteus vulgaris 650
Escherichia coli 400
Staphylococcus aureus 150

Fungi
Aspergillus niger <10
Penicillium mineoluteum <10
Geotrichum candidum <10

Yeast
Candida albicans <25

Chemical compatibility;
 IPBC 30 is compatible with most raw materials used in the manufacture of industrial and decorative coatings. 
 IPBC 30 compatibility should always be checked and evaluated before use.
ATAMAN CHEMICALS Technical Service;
ATAMAN CHEMICALS technical service staff is available to assist customers in the determination of the optimum use level of biocide required to fully protect their product. 
A dedicated team of microbiologists are on hand at all time to assist customers with all technical enquiries relating to product protection. 
Full microbiological efficacy testing is available.


IPBC 40 Antimicrobial
CAS No. 55406-53-6
EINECS: 259-627-5

Iodopropynyl butylcarbamate (IPBC) is a highly effective fungicide and bactericide. 
Iodopropynyl butylcarbamate (IPBC) is used as a preservative for wood and paints as well as in cosmetic formulations and various consumer products.


IPBC 40 is a patent-pending formulation containing 40% w/w 3- Iodo-2-propynylbutylcarbamate (IPBC) as the active ingredient. 
Depending on the US EPA or European Union definition of a volatile organic compound (VOC), this product contains low to no VOCs. 
In addition, this product is formulated in solution form and exhibits excellent attributes such as low viscosity, easy pumping, no settling of solids, and low freezing point temperature.
IPBC 40 is a broad spectrum preservative and dry film fungicide effective against a wide range of fungal organisms. 
IPBC 40 offers excellent dry film fungal protection in interior and exterior paints, coatings, wood protective stains and above ground wood preservatives. 
IPBC 40 product may also be used as a fungicide in paper coatings, inks, adhesives, sealants and cordage and metalworking fluids.

IPBC 40 does not contain any organo-metallics compounds, and is compatible with both aqueous and solvent based formulations.
 

Antimicrobial Activity
 
The following are typical physical properties of  IPBC 40; they are not to be considered product specifications.
Appearance:    Clear light amber liquid
Viscosity (20°C/68°F): 70-90 centipoises
Specific gravity (25°C/77°F): 1.24-1.26 (typical)
Pounds/gallon:    10.40 -10.50
Decomposition point:    192°C (377.6ºF)
The efficacy of the IPBC active has been tested against various microorganisms by the determination of the Minimum Inhibitory Concentration (MIC).
 

Fungi    MIC (mg/L) of IPBC in nutrient agar
Alternaria alternata    2
Aspergullus niger    2
Aureobasidium pullulans    1
Cephaloascus fragrans    2
Ceratocystis pilfera    1
Chaetomium globususm    5
Cladosporium cladosporoides    2
Gliocladium virens    5
Lentinus tigrinus    2
Penicillum glaucum    1
Phialophora fastigiata    2
 
Sclerophoma pityophila    1
Trichoderma virens    2
Bacteria & Yeasts    
Escherichia coli    1000
Staphylococcus aureus    200
Rhodotorula rubra    20
Sporobolomyces roseus    7.5
 

Applications/ Directions for Use
 
ppm ai = parts per million active ingredient

Reported MIC values shown demonstrate the spectrum of antimicrobial activity of IPBC. 
The MIC test results only demonstrate the innate activity and should not be used as a guide to determine levels to use in your formulations.

Recommended use level*
Application    (% w/w product)    Comments
 
Adhesives    
0.05 – 0.63     
Non-medical, non-food use cycle with good agitation to ensure natural and synthetic adhesive formulations, caulks, patching compounds, sealants,grouts, latexes used in the manufacture of flooring adhesives and carpet backings.
 
Cordage    
0.05 – 2.50    
Aqueous and solvent based process formulations which coat cordage.    .
 
Textiles: 0.05 – 2.50    
For use in both aqueous and solvent-based Carpet fibers, carpet backing, canvas,coatings or dyes cordage, drapes and shower curtains    

Inks    
0.125 - 7.50    

 
Paints & Coatings, exterior    
0.25 - 2.00        


Plastics & Plastics coatings;    
0.125 – 2.50    
Shower curtains, wire & cable insulation and sun umbrellas        . 
        

Paper Coatings.    
0.05 – 2.00    
Paper and cardboard substrates coatings –non-food contact applications only        
        

 
Recommended use level*
Application    (% w/w product)    Comments
Wood treatment – freshly sawn wood    0.25 - 3.00    
For use on wood in above ground application only.

Treating solutions may be prepared by diluting this product in alcohols or aromatic solvents or by dispersion in water.
Suggested levels depend upon the severity of conditions for end use and the extent of time that protection is required. 
The treatment can be applied by dip method or spray method.
For best results, lumber should be treated within 24 hours of sawing. 
The lumber should be completely immersed in the treating bath in the dip method, to have required loading of the product and to minimize spillage.
The fresh sawn wood can also be treated with spray treatments using various spray technologies such as lateral or in-line spray booths, Flood coaters or electrostatic sprayer.

Wood Preservation – wood based    0.25 to 2.00    
The product may be applied by dipping,products-engineered wood products    and millwork *        
brushing, spraying or pressure treatment    
A concentration of 0.25% for mildew control and 0.50% for decay control is normally used. 
However, higher concentration up to 2% is recommended depending on the intended exposure, and length of protection desired.

Wood stains.    
0.25 –2.00    For use on wood in above-ground interior or exterior protective coatings        
Preservation of surface    
0.25 - 1.25    
For treatment of tiling joint fillers, grouts,and building materials**        
plaster plates applied on buildings (indoor) and surface materials applied on buildings (e.g., cement layer, plaster).

Metalworking fluids.    
≤ 0.25    
Only can be used in MWF concentrates.
Synthetic, semi-synthetic & soluble Cutting, Cooling & Lubricating Fluids.    diluted MWF.    
        
        
 

Safety & Labeling Handling
 
*These are recommended use levels; laboratory evaluation and field trials are suggested in order to determine the optimum levels and cost effective use for IPBC 40 in a given end application. 

Please refer to the Safety Data Sheet and product label.

Keep away from heat, sparks, and flame. Avoid contact with eyes, skin, and clothing. Avoid breathing vapor. Use with adequate ventilation. When handling products directly, personal protective equipment, including chemical splash goggles, chemically resistant gloves and apron should be worn.
 
Storage

Product disposal

Spill Handling

Shelf life: Two years from production date when stored as directed.     
Storage: 4°C to 32°C [39°F to 90°F]. 
Containers should not be exposed to direct sunlight. 
Do not store with strong oxidizing agents or strong (concentrated) acids.    

Do not contaminate water, food or feed by storage or disposal. 
Excess product and rinse water has to be disposed according to local regulations for disposal. 
A small quantity of IPBC 40 will likely remain in the container; this container should be triple rinsed and the rinse water should be treated as waste. 
To ensure that containers are not reused, they should be pierced before disposal.

259-627-5 [EINECS]
3-Iod-2-propin-1-yl-butylcarbamat [German] [ACD/IUPAC Name]
3-Iod-2-propin-1-yl-hydrogenbutylkohlenstoffimidat [German] [ACD/IUPAC Name]
3-Iodo-2-propyn-1-yl butylcarbamate [ACD/IUPAC Name]
3-Iodo-2-propyn-1-yl hydrogen butylcarbonimidate [ACD/IUPAC Name]
3-Iodo-2-propynyl butylcarbamate
3-Iodo-2-propynyl N-butylcarbamate
3-iodo-2-propynyl-butylcarbamate
3-Iodo-2-propynylbutylcarbamate
3-Iodo-2-propynyl-N-butylcarbamate
55406-53-6 [RN]
Butylcarbamate de 3-iodo-2-propyn-1-yle [French] [ACD/IUPAC Name]
Carbamic acid, N-butyl-, 3-iodo-2-propyn-1-yl ester [ACD/Index Name]
EZ0950000
Hydrogénobutylcarbonimidate de 3-iodo-2-propyn-1-yle [French] [ACD/IUPAC Name]
I1UU2OVM4 [WLN]
Iodocarb
Iodopropynyl butylcarbamate [Wiki]
Ipbc
Methanol, 1-(butylimino)-1-[(3-iodo-2-propyn-1-yl)oxy]-, (Z)- [ACD/Index Name]
MFCD00072438 [MDL number]
?????????????????????????????????(ipbc)
[55406-53-6]
1-Iodoprop-1-yn-3-yl N-n-butylcarbamate
1-Phenyl-1,2-dihydroisoquinolin-3(4H)-one
3-iodo-2-propyn-1-yl N-butylcarbamate
3-iodo-2-propynyi butylcarbamate
3-Iodo-2-propynyl butyl carbamic acid
3-iodo-2-propynyl n-butylcarbamate 97%
3-iodo-2-propynyl n-butylcarbamate, ???
3-iodo-2-propynyl n-butylcarbamate
3-iodo-2-propynyl??n-butylcarbamate
3-Iodo-2-propynylbutyl carbamate
3-iodoprop-2-yn-1-yl N-butylcarbamate
3-iodoprop-2-ynyl butylcarbamate
3-iodoprop-2-ynyl N-butylcarbamate
3-Iodopropynyl butylcarbamate
3-IPBC
'55406-53-6
Butyl-3-iodo-2-propynylcarbamate
C106572
Carbamic acid, butyl-, 3-iodo-2-propynyl ester
carbamic acid, butyl-, 3-iodoprop-2-ynyl ester
Carbamic acid, butyl-3-iodo-2-propynyl ester
EINECS 259-627-5
GS-3240
http:////www.amadischem.com/proen/573922/
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:83279
Iodocarb (IPBC)
Iodocarb 100 µg/mL in Acetonitrile
iodocarbe
iodopropynyl??butylcarbamate
Iodopropynylbutylcarbamate
N-[2-(1-iodoethyl)pent-3-enyl]carbamate
N-butyl(3-iodoprop-2-ynyloxy)carboxamide
N-butylcarbamic acid 3-iodoprop-2-ynyl ester
NCGC00164376-01
OR-0600
Troysan KK-108A
Troysan KK-108A; Troysan polyphase anti-mildew; Woodlife
Troysan polyphase anti-mildew
UNII:603P14DHEB
UNII-603P14DHEB
Woodlife


 

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