LONZABAC 12

Lonzabac 12 is an active material with broad spectrum activity against both gram positive and gram negative bacteria. 
Lonzabac 12 maintains its high efficacy in the presence of heavy organic soiling while also having good surfactant properties. 
Lonzabac 12 is for formulation into antimicrobial/disinfectant product for use on hard nonporous surfaces.

CAS Number: 2372-82-9
Other Name: N-(3-Aminopropyl)-N-dodecylpropane-1,3-diamine
Molecular Formula: C18H41N3
Molecular Weight: 299.5 g/mol

Lonzabac 12 Antimicrobial is a broad-spectrum biocidal active ingredient with good surfactant properties and is compatible with anionic surfactants.
Lonzabac 12 is effective against both gram-positive and gram-negative bacteria as well as Mycobacterium terrae and Mycobacterium avium.

Lonzabac 12 Antimicrobial maintains high efficacy even at low temperatures and in the presence of heavy organic soil, such as blood and protein, and is also effective against enveloped viruses such as Hepatitis-B (HBV). 
Lonzabac 12 is stable across a wide range of pH levels and is usable in formulations for a number of applications such as food processing, institutional, veterinary and medical areas.

Lonzabac 12 Antimicrobial is offered in two product forms, ~27% or ~91% aqueous solution: Lonzabac® 12.30 and Lonzabac® 12.100 respectively.
Lonzabac 12 Antimicrobial is being supported through the European Union Biocidal Products Regulation (BPR)1 Active Substance Review Program for Product Types, 2, 3, 4 and 6, and with the US Environmental Protection Agency (EPA), with full toxicological and ecological documentation.

Solubility of Lonzabac 12:
Lonzabac 12 is compatible with nonionics, cationics, and some anionic surfactants. 
Lonzabac 12 is not compatible with aldehydes.

Description    of Lonzabac 12:
Lonzabac 12 is a novel, non-toxic and biodegradable surfactant that has recently been developed for use in various scientific applications. 
Lonzabac 12 has been found to have a wide range of applications, including synthesis and purification of proteins, liposomes, and other biomolecules; drug delivery systems; and as a detergent for various industrial processes. 

Furthermore, Lonzabac 12 has been found to possess a number of advantageous properties, such as low toxicity, high biodegradability, and excellent solubility in water. 
This article will discuss the synthesis method, scientific research applications, mechanism of action, biochemical and physiological effects, advantages and limitations for lab experiments, and future directions of Lonzabac 12.

Synthesis Method of Lonzabac 12:
Lonzabac 12 is produced by the condensation reaction of N-dodecylpropane-1,3-diamine (DPA) and 3-aminopropylamine (APA). 
The reaction is catalyzed by a base, such as sodium hydroxide, and is conducted at a temperature of around 80°C. 

The reaction is carried out in an aqueous solution, and the product is isolated by precipitation. 
The product is then purified by recrystallization and is then ready for use.

Physical Properties of Lonzabac 12:
Density: ~0.87 g/ml
Viscosity: ~38 mPa/s
Average Molecular Weight: 299
Surface Tension: ~32 mN/m
Freeze Thaw Stability: Good
Setting Point: < 10oC

Typical Prorperties of Lonzabac 12:
Appearance: Clear Liquid
Color, APHA: 300 Max.
Water, KF: 1.5%
Odor: Slight
pH: 10-12

Lonzabac 12 Antimicrobial is a broad-spectrum biocidal active ingredient with good surfactant properties and is compatible with anionic surfactants.

KEYWORDS:
2372-82-9, N-(3-Aminopropyl)-N-dodecylpropane-1 3-diamine, Lonzabac, Grotan BA 21, N N-Bis(3-aminopropyl)dodecylamine, RC 5637, 1 3-Propanediamine N-(3-aminopropyl)-N-dodecyl-, Bis(3-aminopropyl)dodecylamine, Dodecylamine N N-bis(3-aminopropyl)-, N-Dodecyl-Dipropylene Triamines

Scientific Research Applications of Lonzabac 12:
Lonzabac 12 has been found to have a wide range of applications in scientific research. 
Lonzabac 12 has been used as a surfactant for the synthesis and purification of proteins, liposomes, and other biomolecules. 

Lonzabac 12 is also used in drug delivery systems, as it can be used to modify the surface of liposomes to increase their stability and enhance their drug delivery efficiency. 
Additionally, Lonzabac 12 has been used as a detergent for various industrial processes, such as emulsification, extraction, and separation.

Lonzabac 12 mechanism of Action:
Lonzabac 12 has been found to act as an amphiphilic surfactant, meaning that it has both hydrophilic and hydrophobic regions. 
This allows it to form micelles, which are aggregates of molecules that are surrounded by a hydrophilic shell and an inner hydrophobic core. 

These micelles can then interact with the surface of biomolecules, such as proteins, and modify their surface properties. 
This can be used to increase the solubility of proteins, as well as to increase their stability and improve their drug delivery efficiency.

Biochemical and Physiological Effects of Lonzabac 12:
Lonzabac 12 has been found to be non-toxic and biodegradable, making it suitable for use in various scientific applications. 
Furthermore, Lonzabac 12 has been found to have no significant effect on the biochemical and physiological processes of cells.
This makes Lonzabac 12 a safe and reliable surfactant for use in various scientific applications.

Advantages and Limitations for Lab Experiments of Lonzabac 12:
One of the major advantages of Lonzabac 12 is its low toxicity and biodegradability. 
This makes Lonzabac 12 a safe and reliable surfactant for use in various scientific applications. 

Additionally, Lonzabac 12 has been found to be highly soluble in water, which makes it easy to use in laboratory experiments. 
However, Lonzabac 12 has been found to be less effective in some applications, such as the synthesis and purification of proteins, when compared to other surfactants.

Future Directions    of Lonzabac 12:
Lonzabac 12 has a wide range of applications in scientific research, and there are a number of future directions that can be explored. 
These include further investigation into its mechanism of action, as well as its potential applications in drug delivery systems and industrial processes. 

Additionally, Lonzabac 12's potential use in the synthesis and purification of proteins and other biomolecules should be further investigated. 
Finally, further research should be conducted into the biochemical and physiological effects of Lonzabac 12, as well as its potential toxicity.

CAS RN: 2372-82-9
Product Name: N-(3-Aminopropyl)-N-dodecylpropane-1,3-diamine
Molecular Formula: C18H41N3
Molecular Weight: 299.5 g/mol
IUPAC Name: N'-(3-aminopropyl)-N'-dodecylpropane-1,3-diamine
InChI: InChI=1S/C18H41N3/c1-2-3-4-5-6-7-8-9-10-11-16-21(17-12-14-19)18-13-15-20/h2-20H2,1H3
InChI Key: NYNKJVPRTLBJNQ-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCN(CCCN)CCCN
Canonical SMILES: CCCCCCCCCCCCN(CCCN)CCCN
Other CAS RN: 2372-82-9
Physical Description: Liquid
Pictograms: Corrosive; Acute Toxic; Health Hazard; Environmental Hazard
Synonyms: Grotan BA 21;  Lonzabac 12;  Lonzabac 12.100;  Lonzabac 12.30;  Lonzabac 1230; _x000B_Mistral;  N,N-Bis(3-aminopropyl)dodecylamine;  N,N-Bis(3-aminopropyl)laurylamine; _x000B_RC 5637;  Triameen Y 12;  Triameen Y 12D;  Triamine Y 12D; 

Product Information:
Name:
N-​(3-​Aminopropyl)​-​n-​dodecylpropane-​1,​3-​diamine

Description of Lonzabac 12:
Catalogue Number: A894750
Chemical Name: N-​(3-​Aminopropyl)​-​n-​dodecylpropane-​1,​3-​diamine (>80%)
Synonyms: Grotan BA 21; Lonzabac 12; Lonzabac 12.100; Lonzabac 12.30; Lonzabac 1230;
CAS Number: 2372-82-9
Molecular Formula: C₁₈H₄₁N₃
Appearance: Colourless Oil
Molecular Weight: 299.54
Storage: 4°C
Solubility: Chloroform (Soluble), Methanol (Soluble)
Applications: N-​(3-​Aminopropyl)​-​n-​dodecylpropane-​1,​3-​diamine is a reactant used in the synthesis of gluconamide derivatives as cationic surfactants with antimicrobial properties.

Lonzabac 12 DIRECTIONS FOR USE:
Lonzabac 12 is a violation of Federal Law to use this product in a manner inconsistent with its labeling.
For formulation into antimicrobial/disinfectant products for use on hard, non-porous non-food contact surfaces in: businesses and office buildings, hotels, motels, correctional facilities, athletic facilities, schools, barber shops, locker rooms, nonfood areas of food-processing plants and restaurants, bars and cafeterias, convenience rooms, public restrooms, animal laboratories, pet shops, factories, and medical facilities including: hospitals, clinics, nursing homes and other medical offices.

Lonzabac 12 can also be used to formulate products used to control antimicrobial contamination in oil field water flood systems and metalworking fluids.
Formulators using Lonzabac 12 are responsible for providing data for the EPA registration of their formulated products. 

Lonzabac 12 STORAGE AND DISPOSAL:
Do not contaminate water, food or feed by storage or disposal.

PESTICIDE STORAGE of Lonzabac 12: 
Store Lonzabac 12 upright in original container and place in a locked storage area inaccessible to children. 
Do not reuse empty container.

PESTICIDE DISPOSAL of Lonzabac 12: 
Pesticide wastes are acutely hazardous. 
Improper disposal of excess pesticide, spray mixture or rinsate is a violation of Federal Law.
If these wastes cannot be disposed of by use according to label instructions, contact your state pesticide or Environmental Control Agency, or Hazardous Waste Representative at the nearest EPA Regional Office for guidance.

CONTAINER DISPOSAL of Lonzabac 12: 
Nonrefillable container. 
Do not reuse or refill this container.

Plastic and Metal Containers: 
Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank. 
Fill the container ¼ full with water. 
Replace and tighten closures. 

Tip container on its side and roll it back and forth, ensuring at least one complete revolution, for 30 seconds. 
Stand the container on its end and tip it back and forth several times. 

Turn the container over onto its other end and tip it back and forth several times. 
Empty the rinsate into application equipment or a mix tank or store rinsate for later use or disposal.

Repeat this procedure two more times. 
Then offer for recycling or reconditioning.
 
If not available, puncture and dispose in sanitary landfill. 
If not triple rinsed, these containers are acute hazardous wastes and must be disposed in accordance with local, state, and federal regulations. 

FIRST AID of Lonzabac 12:
Have Lonzabac 12 container or label with you when calling a poison control center or doctor, or going for treatment.

IF ON SKIN OR CLOTHING: 
Take off contaminated clothing. 
Rinse skin immediately with plenty of water for 15-20 minutes. 
Call a poison control center or doctor for treatment advice.

IF IN EYES: 
Hold eye open and rinse slowly and gently with water for 15-20 minutes. 
Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. 
Call a poison control center or doctor for treatment advice.

IF INHALED: 
Move person to fresh air. 
If person is not breathing, call 911 or an ambulance, then give artificial respiration, preferably by mouth-to-mouth if possible. 
Call a poison control center or doctor for treatment advice.

IF SWALLOWED: 
Call a poison control center or doctor immediately for treatment advice. 
Have person sip a glass of water if able to swallow. 

Do not induce vomiting unless told to do so by a poison control center or doctor. 
Do not give anything by mouth to an unconscious person.

NOTE TO PHYSICIAN: 
Probable mucosal damage may contraindicate the use of gastric lavage

Synonyms:
Grotan BA 21
Lonzabac 12
Lonzabac 12.100
Lonzabac 12.30
Lonzabac 1230
Mistral
N,N-Bis(3-aminopropyl)dodecylamine
N,N-Bis(3-aminopropyl)laurylamine
RC 5637
Triameen Y 12
Triameen Y 12D
Triamine Y 12D
1,3-Propanediamine, N-(3-aminopropyl)-N-dodecyl-
1,3-Propanediamine, N¹-(3-aminopropyl)-N¹-dodecyl-
Bis(3-aminopropyl)dodecylamine
Dodecylamine, N,N-bis(3-aminopropyl)-
N-(3-aminopropyl)-N-dodecylpropane-1,3-diamine
N-Dodecyl-Dipropylene Triamines
N¹-(3-Aminopropyl)-N¹-dodecyl-1,3-propanediamine
Rc 5637