N-Lauroylsarcosine sodium salt is used for solubilization and separation of membrane proteins and glycoproteins; reported to inhibit hexokinase.
N-Lauroylsarcosine sodium salt is useful in concentrated salt solutions used in the cell lysis step during RNA purification (helps avoid excessive foaming).
CAS Number: 137-16-6
EC Number: 205-281-5
Molecular Formula: CH3(CH2)10CON(CH3)CH2COONa
Other names: Glycine N-methyl-N-(1-oxododecyl)-, Sarcosine N-lauroyl-, N-Methyl-N-(1-oxododecyl)glycine, Lauroylsarcosine, N-Lauroylsarcosine, Sarkosyl L, N-Lauroyl-N-methylaminoacetic acid, Sarcosyl L, N-Laurylsarcosine, Hamposyl L, Maprosyl L, N-Dodecanoylsarcosine, Nikkol Sarcosinate LH, Crodasinic L, Sarcosinate LH, N-Dodecanoyl-N-methylglycine, N-Lauroyl-N-methylglycine, NSC 96994, N-Dodecanoylsarcosinate, Lauroylsarcosinate, Soypon SLA, 2-(N-Methyldodecanamido)acetic acid, 2-[Dodecanoyl(methyl)amino]acetic acid
N-Lauroylsarcosine sodium salt has been used to indicate paramagnetic anisotropy sign change in micelle mesophage.
N-Lauroylsarcosine sodium salt inhibits bacterial flora of human saliva/gut at 0.25% as well as acting as a fungistatic agent in aqueous dispersion (1%).
N-Lauroylsarcosine sodium salts are reportedly are non-irritant and non-sensitizing in human skin, but they can increase the penetration of other substances through the skin and should therefore be used with caution when formulating cosmetic products that contain with other substances whose safety is based on their lack of absorption or if transdermal absorption is a concern.
N-Lauroylsarcosine sodium salt is an anionic surfactant, especially suitable for the preparation of shampoo, Bath, facial cleanser, baby detergent, dishwashing detergent, etc.
N-Lauroylsarcosine sodium salt is derived from sarcosine, a natural amino acid found in the human body and just about every type of biological material from animals to plants. Honest’s sarcosine is made from coconut oil.
N-Lauroylsarcosine sodium salt is a cleanser and foaming agent that helps with the effectiveness and feel of our toothpaste.
Molecular Weight: 271.40 g/mol
XLogP3-AA: 4.5
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 12
Exact Mass: 271.21474379 g/mol
Monoisotopic Mass: 271.21474379 g/mol
Topological Polar Surface Area: 57.6Ų
Heavy Atom Count: 19
Complexity: 254
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Functions of N-Lauroylsarcosine sodium salt:
Antistatic:
Reduces static electricity by neutralizing the electrical charge on a surface
Cleaning agent:
Helps keep a surface clean
Emulsifying agent:
Promotes the formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil)
Foaming agent:
Captures small bubbles of air or other gases in a small volume of liquid by changing the surface tension of the liquid
Hair conditioner:
Leaves hair easy to comb, supple, soft and shiny and/or gives volume, lightness and shine
Skin conditioning agent:
Keeps the skin in good condition
Surfactant:
Reduces the surface tension of cosmetics and contributes to the even distribution of the product during use
Viscosity control agent:
Increases or decreases the viscosity of cosmetics
N-Lauroylsarcosine sodium salt is a cleansing and foaming agent, but that is where the similarities end.
N-Lauroylsarcosine sodium salt is derived from sarcosine, an amino acid that occurs naturally in the body, sodium lauroyl sarcosinate is frequently heralded for being a thorough cleanser but also for being gentle.
N-Lauroylsarcosine sodium salt is an anionic detergent.
N-Lauroylsarcosine sodium salt has been used as one of the components of the lysing solution in the cornet assay.
N-Lauroylsarcosine sodium salt has been used for lysing protoplasts in the process of chromosomal DNA isolation form.
N-Lauroylsarcosine sodium salt is an anionic surfactant which also has protein denaturant potency.
In addition, N-Lauroylsarcosine sodium salt has been shown as a microbicide for sexually transmitted diseases.
N-Lauroylsarcosine sodium salt is an anionic surfactant derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste, and foam wash products.
N-Lauroylsarcosine sodium salt is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.
Since the nitrogen atom is in an amide linkage, the nitrogen is not pH active and is neutrally charged in all aqueous solutions regardless of pH.
N-Lauroylsarcosine sodium salt has a pKa of about 3.6 and is therefore negatively charged in solutions of pH greater than about 5.5.
PH-sensitive vesicles can be prepared using this surfactant with another cationic or water-insoluble amphiphiles such as 1-decanol.
Addition of an mixture of equal parts of N-Lauroylsarcosine sodium salt and the non-ionic surfactant sorbitan monolaurate (S20) to water led to the formation of micelle-like aggregates, even though neither surfactant formed micelles when present alone.
Such aggregates can help carry other small molecules, such as drugs, through the skin.
N-Lauroylsarcosine sodium salt was sold as a special ingredient called "Gardol" in Colgate "Dental Cream", as toothpaste was then called.
N-Lauroylsarcosine sodium salts current use as a preventive dentifrice is in where it is used as a surfactant.
N-Lauroylsarcosine sodium salt works by attracting excess oil and dirt, then carefully removing the grime from the hair by emulsifying it so it rinses easily away with water.
In addition to cleaning the hair, regular use of a shampoo with N-Lauroylsarcosine sodium salt has also been shown to improve the appearance of the hair (especially locks that are damaged) by boosting shine and body.
N-Lauroylsarcosine sodium salt is a powerful anionic surfactant consisting of sarcosine and its sodium salt with functional benefits including foaming, wetting, salt tolerant, and biodegradable.
N-Lauroylsarcosine sodium salt is recommended for use in shampoos, mild facial cleansers, body washes and foam baths, baby products, liquid soaps, antibacterial hand washes, shaving preparations and liquid make-up applications.
N-Lauroylsarcosine sodium salt is known for its good foam-boosing abilities while improving the mildness of the formula.
N-Lauroylsarcosine sodium salts performance is similar to Isethionates, another group of cleaning agents known for their gentleness.
N-Lauroylsarcosine sodium salt was employed as a selective flotation collector for dolomite–apatite separation.
The influence of pH, condition time, and collector dose on the flotation performance of both apatite and dolomite minerals was investigated using single mineral and binary mixed mineral flotation experiments.
N-Lauroylsarcosine sodium salt is an ionic surfactant. Sodium salt of lauroyl sarcosine is widely used in the cosmetic industry in shampoos, body washes, facial washes, foundations, bath soaps, and detergents.
N-Lauroylsarcosine sodium salt is used in noncoloring shampoos, bath soaps, and detergents.
N-Lauroylsarcosine sodium salt is a cleanser and foaming agent that helps with the effectiveness and feel of our toothpaste.
KEYWORDS:
137-16-6, 205-281-5, Sarkosyl NL, Sodium N-lauroylsarcosina, Sodium lauroyl sarcosinate, Glycine N-methyl-N-(1-oxododecyl)- sodium salt, Hamposyl L-30, Medialan LL-99, Sarcosyl NL 30, Sarkosyl NL 30
Besides N-Lauroylsarcosine sodium salts use in cosmetic industry, lauroyl sarcosinate is used in adhesives and as an additive in polymers (with a maximal concentration of 0.35% according to the FDA.
N-Lauroylsarcosine sodium salt is an anionic surfactant.
N-Lauroylsarcosine sodium salt used for cell lysis in RNA extraction protocols as it does not produce excess foaming.
N-Lauroylsarcosine sodium salt is mild and biodegradable anionic surfactants derived from fatty acids and sarcosine (amino acid).
N-Lauroylsarcosine sodium salts features lather building and resistance to sebum delathering in cleaners, polymers, industrial chemicals, petroleum and lubricant products.
N-Lauroylsarcosine sodium salt is often seen in shampoos, bath, cleansing and shaving products as a foaming agent, surfactant, and hair conditioning agent.
N-Lauroylsarcosine sodium salt has the ability to enhance the appearance and feel of hair by improving body, suppleness and sheen, especially in hair that is chemically damaged.
N-Lauroylsarcosine sodium salt also serves to clean skin and hair by mixing with oil and dirt and enabling them to be rinsed away.
About N-Lauroylsarcosine sodium salt Helpful information:
N-Lauroylsarcosine sodium salt is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
N-Lauroylsarcosine sodium salt is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Consumer Uses of N-Lauroylsarcosine sodium salt:
N-Lauroylsarcosine sodium salt is used in the following products: washing & cleaning products, lubricants and greases, cosmetics and personal care products, biocides (e.g. disinfectants, pest control products), polishes and waxes and air care products.
Other release to the environment of N-Lauroylsarcosine sodium salt is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).
Service life of N-Lauroylsarcosine sodium salt:
Other release to the environment of N-Lauroylsarcosine sodium salt is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).
N-Lauroylsarcosine sodium salt can be found in products with material based on: fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys).
Widespread uses by professional workers of N-Lauroylsarcosine sodium salt:
N-Lauroylsarcosine sodium salt is used in the following products: washing & cleaning products, biocides (e.g. disinfectants, pest control products), coating products, inks and toners, polishes and waxes, cosmetics and personal care products, laboratory chemicals, air care products, non-metal-surface treatment products, hydraulic fluids, lubricants and greases and metal working fluids.
N-Lauroylsarcosine sodium salt is used in the following areas: formulation of mixtures and/or re-packaging, agriculture, forestry and fishing and health services.
Other release to the environment of N-Lauroylsarcosine sodium salt is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).
Formulation or re-packing of N-Lauroylsarcosine sodium salt:
N-Lauroylsarcosine sodium salt is used in the following products: washing & cleaning products, biocides (e.g. disinfectants, pest control products), polishes and waxes, cosmetics and personal care products, coating products, air care products, non-metal-surface treatment products, inks and toners and laboratory chemicals.
N-Lauroylsarcosine sodium salt has an industrial use resulting in manufacture of another substance (use of intermediates).
Release to the environment of N-Lauroylsarcosine sodium salt can occur from industrial use: formulation of mixtures.
Uses at industrial sites of N-Lauroylsarcosine sodium salt:
N-Lauroylsarcosine sodium salt is used in the following products: washing & cleaning products, biocides (e.g. disinfectants, pest control products), polishes and waxes, cosmetics and personal care products, coating products, laboratory chemicals, air care products, non-metal-surface treatment products, hydraulic fluids, inks and toners and lubricants and greases.
N-Lauroylsarcosine sodium salt has an industrial use resulting in manufacture of another substance (use of intermediates).
N-Lauroylsarcosine sodium salt is used in the following areas: formulation of mixtures and/or re-packaging.
N-Lauroylsarcosine sodium salt is used for the manufacture of: chemicals and machinery and vehicles.
Release to the environment of N-Lauroylsarcosine sodium salte can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid, as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates) and of substances in closed systems with minimal release.
Manufacture of N-Lauroylsarcosine sodium salt:
Release to the environment of N-Lauroylsarcosine sodium salt can occur from industrial use: manufacturing of the substance.
As a modified fatty acid, N-Lauroylsarcosine sodium salt is thought to be more soluble, and have increased crystallinity and acidity compared to its original fatty acid composition.
N-Lauroylsarcosine sodium salt can reduce the irritation caused by the residue of traditional surfactants on the skin with it's good compatibility properties.
As N-Lauroylsarcosine sodium salt has good biodegrability, N-Lauroylsarcosine sodium salt is in accordance with the requirement of environmental protection.
N-Lauroylsarcosine sodium salt is very mild, but also very effective.
What’s more, FDA approved as an indirect food additive, and CIR approved when used in rinse-off products, or in leave-on products at concentrations of 5% or less.
N-Lauroylsarcosine sodium salt has a wide range of application because of it's good foambility in comparatively wider PH value range.
N-Lauroylsarcosine sodium salt has good resistance to hard water, good foam stability, and is less affected by hard water than other types of surfactants.
Because sulfate-free, N-Lauroylsarcosine sodium salt is widely used in shampoos, especially in anti-dandruff shampoo.
The reason is N-Lauroylsarcosine sodium salt contributes to the suspension of ZPT，also anti-dandruff agent has certain irritation to the hair.
N-Lauroylsarcosine sodium salt can significantly reduce the side effects, and reduce excessive degreasing, so that the scalp is not dried after washing, reducing dandruff caused by scratching and infection.
N-Lauroylsarcosine sodium salt are mild, biodegradable anionic surfactants derived from fatty acids and sarcosine.
N-Lauroylsarcosine sodium salt is used as a foaming and cleansing agent for shampoo, shaving foams and foam washes.
N-Lauroylsarcosine sodium salt is used as a corrosion inhibitor and in formulating textile treatment agents.
N-Lauroylsarcosine sodium salt is the salt of lauryl sarcosine.
N-Lauroylsarcosine sodium salt is a powder or liquid and is derived from coconut.
N-Lauroylsarcosine sodium salts grow around the world in lowland tropical and subtropical areas where annual precipitation is low.
Widely cultivated, healthy N-Lauroylsarcosine sodium salts produce 50 nuts per year, and the tree can be used to produce everything from food and drink to fibers, building materials, and natural ingredients.
N-Lauroylsarcosine sodium salt is a surfactant that allows water and oil to mix, allowing things to become clean.
N-Lauroylsarcosine sodium salt also acts as a conditioning agent.
N-Lauroylsarcosine sodium salt can be found in hundreds of personal care products such as shampoo, shaving cream, facial cleanser, soap, makeup, and other products.
N-Lauroylsarcosine sodium salt is made with coconut acid and sarcosine, which is a breakdown product of creatine or caffeine.
N-Lauroylsarcosine sodium salt is a natural amino acid found in muscle and body tissue.
Commercially, the ingredient is made in the presence of sodium hydroxide; N-Lauroylsarcosine sodium salt is then purified by recrystallizing it from alcohol or by acidifying it with mineral acid, separating the free acid, and neutralizing the free acid.
N-Lauroylsarcosine sodium salt is a much milder anionic surfactant than sulfate compounds.
N-Lauroylsarcosine sodium salt is derived from fatty acids and natural amines.
N-Lauroylsarcosine sodium salt is used in the composition of gentle cleansing products and is also used in toothpastes.
Uses of N-Lauroylsarcosine sodium salt:
N-Lauroylsarcosine sodium salt is a white powder derived from sarcosine, which make it is fate-free and biodegradable.
N-Lauroylsarcosine sodium salt is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.
N-Lauroylsarcosine sodium salt is personal care products as well as in household and industrial applications.
N-Lauroylsarcosine sodium salt is used as a co-surfactant in cleanser formulations such as shampoos and body washes.
N-Lauroylsarcosine sodium salt can also be used in oral care applications such as toothpastes and incorporated into syndet and combo bars.
The typical usage levels range from 1-5% on an active basis.
N-Lauroylsarcosine sodium salt is used for solubilization and separation of membrane proteins and glycoprotein's; reported to inhibit hexokinase.
N-Lauroylsarcosine sodium salt is useful in concentrated salt solutions used in the cell lysis step during RNA purification (helps avoid excessive foaming).
N-Lauroylsarcosine sodium salt has been used to indicate paramagnetic anisotropy sign change in micelle mesophage.
N-Lauroylsarcosine sodium salt is an anionic surfactant with an ability to denature proteins.
Due to N-Lauroylsarcosine sodium salts microbicidal property, N-lauroylsarcosine is being considered as a potent anti-microbicide in topical formulations, especially against sexually transmitted diseases (STDs).
N-Lauroylsarcosine sodium salt is an anionic surfactant which also has protein denaturant potency.
In addition, N-Lauroylsarcosine sodium salt has been shown as a microbicide for sexually transmitted diseases.
APPLICATIONS of N-Lauroylsarcosine sodium salt:
N-Lauroylsarcosine sodium salt is mild, biodegradable anionic surfactants derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste, and foam wash products.
N-Lauroylsarcosine sodium salt is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.
N-Lauroylsarcosine sodium salt is a high foam, eco-friendly surfactant.
N-Lauroylsarcosine sodium salt has good chlorine stability with anti-corrosion properties.
N-Lauroylsarcosine sodium salt has excellent ocular tolerance and gentleness.
N-Lauroylsarcosine sodium salt is often seen in shampoos, bath, cleansing and shaving products as a foaming agent, surfactant, and hair conditioning agent.
N-Lauroylsarcosine sodium salt has the ability to enhance the appearance and feel of hair by improving body, suppleness and sheen, especially in hair that is chemically damaged.
N-Lauroylsarcosine sodium salt also serves to clean skin and hair by mixing with oil and dirt and enabling them to be rinsed away.
As a modified fatty acid, N-Lauroylsarcosine sodium salt is thought to be more soluble, and have increased crystallinity and acidity compared to its original fatty acid composition.