NIPACIDE CFX 3


Nipacide CFX 3 is a low toxicity biocide specifically developed for the complete microbiological protection of water based products against bacterial and fungal spoilage in the wet state, particularly where it is to be used at high ambient temperatures. This product is a water based liquid. It is described chemically as a blend of chlorinated and non-chlorinated isothiazolinones plus ethyl glycol bis hemiformal.

A unique stabilisation system has been developed and incorporated into Nipacide CFX/3. Nipacide CFX 3 is recommended for a wide range of applications including adhesives, polymer emulsions, fountain solutions, MWF and paint where protection against fungi and bacteria is required in the wet state.


Composition
Combination of 5 – Chloro – 2 – methyl -isothiazolin – 3 - one (CIT) / 2 – Methyl –isothiazolin – 3 - one (MIT) and 1,6 –dihydroxy - 2,5 – dioxahexane.


Nipacide CFX 3 is In-can biocide based on CMIT/MIT + EDDM.It is a mixture of isothiazolinones andformaldehyde releaser and provides also head-space protection.


Product properties*
Active content
CIT / MIT : 0.8 - 1.0%.
1,6–dihydroxy-2,5–dioxahexane: 9.0 – 12.0%

Appearance
Colourless to Yellow, clear liquid
pH (neat): 2.0 – 4.0

Specific Gravity at 20⁰C: 1.020 – 1.100

Solubility in water: Soluble

Description
Nipacide CFX 3-IN is a water based, liquid biocide specifically developed for the complete in-can microbiological protection of industrial water based products against bacterial and fungal spoilage in the wet state. 


Applications
Nipacide CFX 3-IN is recommended for the preservation of a wide range of applications including water based adhesives, polymer emulsions, water based decorative paints, metal working fluids, sealants and tile grouts, household detergent cleaners, car care products and construction chemicals where protection against fungi and bacteria is required in the wet state. 
It is effective against a wide range of common spoilage organisms including gram positive and gram negative bacteria, yeast and fungi. 
It can be used over a pH range 4 - 9 and temperature range up to 40°C. 
Nipacide CFX 3-IN is particularly effective at providing head space protection, in-can, by the slow release of formaldehyde.


Microbiological Data
Nipacide CFX 3-IN exhibits a broad spectrum of activity which is demonstrated by the following
MIC data against some common microorganisms associated with wet-state spoilage:

Organism MIC (ppm) Organism MIC (ppm)
Bacteria: Fungi:
Pseudomonas aeruginosa 400 
Aspergillus niger 150
Pseudomonas putida 400 
Penicillium mineoluteum 75
Proteus vulgaris 125 
Fusarium solani 125
Escherichia coli 500 
Geotrichum candidum 200
Staphylococcus aureus 550 
Yeast:
Candida albicans 150

Chemical Compatibility
Nipacide CFX 3-IN is compatible with most raw materials used in the manufacture of industrial and decorative coatings. 
However it is recommended that the compatibility of Nipacide CFX 3-IN with the application should always be checked and evaluated before use.

Use Levels
Nipacide CFX 3-IN should be evaluated in finished products at levels between 0.1% and 0.3%. 
Please note that Nipacide CFX 3-IN above 0.16% requires R43 (causes sensitization by skin contact) hazard labeling. 

The level of protection required will depend on many factors including the degree of contamination of raw materials and the susceptibility of the final product.

Clariant Technical Service
Clariant technical service staff is available to assist customers in the determination of the optimum use level of biocide required to fully protect their product. 
The staff is on hand at all times to assist customers with all technical enquiries relating to product protection. 

Full microbiological efficacy testing is available at the Clariant Microbiology Laboratory. 

Nipacide® CFX 3 by Clariant is a low toxicity, in-can biocide based on formaldehyde, chloromethyl and methylisothiazolinone. 
It is a water-based isothiazolinone/ formaldehyde donor biocide developed for complete head space protection of water-based products. 
It is effective against gram positive and gram negative bacteria, yeast and fungi over a wide pH and temperature range. 
Nipacide CFX 3 complies with FDA regulation.

Nipacide CFX 3 is an in-can biocide based on formaldehyde + chloromethyl and methylisothiazolinone. 

Nipacide CFX 3 is a water-based low toxicity isothiazolinone/ formaldehyde donor biocide, developed for the complete in-can and head space protection of water-based products. Nipacide CFX 3 is effective against a wide range of microorganisms including gram positive and gram negative bacteria, yeast and fungi.

When products are prone to surface contamination by fungi and head space protection is required, Nipacide CFX 3 should be the biocide of choice. 
Nipacide CFX 3 is effective against a wide range of spoilage organisms effective over a wide pH and temperature range.

Benefits
provides heat-space protection
bactericide
fungicide
pH stable 4-9
temperature stable up to 40° C
FDA approved for various applications

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