NIPACIDE OIT

Nipacide OIT.
Chemical name: n-octyl isothiazolin-one

Nipacide OIT is a low toxicity biocide specifically developed for the complete microbiological protection of water based and solvent based products against algal and fungal spoilage in the dry state. Nipacide OIT is a Glycol based liquid. 
Nipacide OIT is described chemically as a solution of 2-octyl-2H-isothiazoline-3-one. 
Nipacide OIT is recommended for a wide range of applications including paints, adhesives and sealants where protection is required in the dry state.

EC / List no.: 247-761-7
CAS no.: 26530-20-1

Description; 
Nipacide OIT is a clear glycolic solution, dry film fungicide, free from Carbendazim and diuron. 
Nipacide OIT has been developed for the complete dry film protection of water based coatings. 
Nipacide OIT is effective against a wide range of fungal and algal species, responsible for the discoloration and degradation of surface coatings. 
Dry –film degradation in paints and decorative coatings can be avoided by using the correct dry-film fungicides at the most cost effective use level. 
Ideal dry-film properties achieved by Nipacide OIT include: 
• High activity against a broad range of fungi and algae 
• Excellent activity at relatively low use concentrations 
• Carbendazim free 
• Diuron free 
• UV stable 
• Approved under the Biocidal Products Directive 
• Cost effective protection 

Applications; 
Nipacide OIT is recommended for protection of a wide range of coating applications including water based decorative paints, wood stains and colours. 
Nipacide OIT can also be used in solvent based applications. 
Nipacide OIT is effective against a wide range of spoilage moulds and yeasts. 

Use level; 
Nipacide OIT should be evaluated in finished products at levels between 0.20% and 1.0%. 
The level of protection will depend on many factors including the end destination of coating, relative humidity, sun strength and others and can be determined by evaluation by our team of microbiologists at the Clariant Microbiology facility

Microbiological data;
Even though Nipacide OIT is designed for dry-film applications it also exhibits activity against a wide range of bacteria, fungi and yeast. 
This can be demonstrated by the following MIC data.
MIC Levels Organism MIC (ppm)
Bacteria
Pseudomonas aeruginosa 500
Proteus vulgaris 30
Escherichia coli 125
Staphylococcus aureus 10
Fungi
Aspergillus niger 8
Penicillium glaucum 3
Rhizopus nigricans 75
Chaetomium globosum 25
Yeast
Candida albicans 5
Rhodotorula rubra 5


Chemical compatibility;
Nipacide OIT is compatible with most raw materials used in the manufacture of industrial and decorative coatings. 
Nipacide OIT compatibility should always be checked and evaluated before use.

Clariant Technical Service;
Clariant technical service staff is available to assist customers in the determination of the optimum use level of biocide required to fully protect their product. 
A dedicated team of microbiologists are on hand at all time to assist customers with all technical enquiries relating to product protection. 
Full microbiological efficacy testing is available.


Octhilinone

26530-20-1

2-n-Octyl-4-isothiazolin-3-one

2-Octyl-4-isothiazolin-3-one

2-octylisothiazol-3(2H)-one

2-Octyl-3-isothiazolone

Pancil

2-Octyl-2H-isothiazol-3-one

3(2H)-Isothiazolone, 2-octyl-

Kathon 893

2-Octyl-3(2H)-isothiazolone

Skane 8

Skane M-8

Kathon 893F

Micro-chek skane

Kathon LM

Microbicide M-8

2-octyl-1,2-thiazol-3-one

Micro-chek 11

Micro-chek 11D

Kathon SP 70

Kathon LP preservative

Kathon 4200

4-Isothiazolin-3-one, 2-octyl-

UNII-4LFS24GD0V

Octyl-3(2H)-isothiazolone

RH 893

2-Octyl-3-isothioazolone

2-Octyl-3-isothiazolinone

Octyl-4-isothiazol-3-one

2-n-Octyl-3-isothiazolone

4LFS24GD0V

MLS002415697

CHEBI:81936

SMR001370885

DSSTox_CID_5805

Pancil-T

DSSTox_RID_77928

DSSTox_GSID_25805

Skane M8

Caswell No. 613C

Kathon

Vinylzene IT 3000DIDP

CAS-26530-20-1

Octhilinone [ANSI:BSI:ISO]

CCRIS 6082

EINECS 247-761-7

EPA Pesticide Chemical Code 099901

BRN 1211137

C11H19NOS

Pancil T

2-octyl-1,2-thiazol-3(2H)-one

Skane M 8

ACMC-1CDE4

Vinyzene IT 3000DIDP

SCHEMBL15648

cid_33528

KSC163A4D

SCHEMBL396433

CHEMBL1562104

DTXSID1025805

BDBM66023

HSDB 6713

KS-00000ZYZ

2-Octyl-4-Isothiazolin-3-Ketone

ZINC2012904

Tox21_201459

Tox21_300566

ANW-26014

MFCD00072473

RH-893

AKOS015897428

NCGC00091875-01

NCGC00091875-02

NCGC00091875-03

NCGC00091875-04

NCGC00091875-05

NCGC00254466-01

NCGC00259010-01

AS-11894

Octhilinone 10 microg/mL in Acetonitrile

2-Octyl-3(2H)-isothiazolone, Octhilinone

DB-028182

FT-0613248

O0343

O0378

C18752

K-6861

530O201

Q2013949

W-107168

2-Octyl-4-isothiazolin-3-one, PESTANAL(R), analytical standard

Octhilinone is a member of the class of 1,2-thiazole that is 1,2-thiazol-3-one substituted on the nitrogen (position 2) by an octyl group. 
A fungicide and antibacterial agent, it is used for treatment of canker and other fungal and bacterial diseases in fruit trees.

2-octyl-3-isothiazolone is a clear dark amber liquid. 
Used as a fungicide.

2-n-Octyl-4-isothiazolin-3-one is a member of the chemically related isothiazolinone group of preservatives. 2-N-octyl-4-isothiazolin-3-one (OIT) is an antimicrobial agent that is mainly used in industrial settings.


Skin contact with 2-n-Octyl-4-isothiazolin-3-one is required for it to cause a rash. Discontinuation of exposure to products containing 2-n-Octyl-4-isothiazolin-3-one should result in improvement and/or resolution of your dermatitis. 
By law, all products made in the US for topical use have the ingredients listed either on the product package or the box that contains it, so check the labeling of you skin care products for this ingredient. If there is no information ask your pharmacist. At work, request a material safety data sheet (MSDS) to help identify potential sources of exposure.

Uses:
Preservative in leather
Paint manufacturing
Bactericide
Biocide
Fungicide in:
Adhesives
Decorative wood stains
Pulp
Water-based Paints
Sealants
Additive in refinery oil
Cutting oils
Wallpaper adhesive, etc.
Cosmetics
Shampoos
Wood
Wound protectant for pruning cuts

Other names for 2-n-Octyl-4-isothiazolin-3-one:
Skane M-8
Kathon 893
2 Octyl-4 isothiazolin-3-one
2-Octyl-3 (2H)-isothiazolone
Octhilinone

Potential cross-reacting/co-reacting substances:
Benz-isothiazolinine
Methylchloroisothiazolinone/Methylisothiazolinone (MCI/MI)
OIT
2-octyl-2H-isothiazol-3-one
2-octylisothiazole-3(2H)-one
NOIT
2-Octyl-3(2H)-isothiazolone
2-octyl-3-isothiazolon
2-Octyl-4-isothiazolin-3-one
Isothiazolone, 2-octyl-
Kathon
Kathon 893
Kathon lp preservative
Kathon sp 70
Microbicide M-8
Micro-chek 11
Micro-chek 11d
Micro-chek skane
Octhilinone
Octyl-3(2H)-isothiazolone
Pancil
pancil-t
RH 893
Skane M-8
Skane hq


Synonyms:
     octhilinone
2-    octyl-1,2-thiazol-3(2H)-one
2-    octyl-1,2-thiazol-3-one
2-    octyl-3(2H)-isothiazolone
2-n-    octyl-4-isothiazolin-3-one
3(2H)-iso    thiazolone, 2-octyl-

2-Octyl-3-isothiazolinone
2-octyl-2H-isothiazol-3-one
2-Octyl-3-isothiazolone
Octyl-4-isothiazol-3-one
Octyl-3(2H)-isothiazolone
2-Octyl-3-isothioazolone
2-Octyl-4-isothiazolin-3-one
2-Octyl-3(2H)-isothiazolone
2-n-Octyl-4-isothiazolin-3-one

Octhilinon
2-Octyl-2H-isothiazol-3-on

Other names: 4-Isothiazolin-3-one, 2-octyl-; Kathon LP Preservative; Octyl-4-isothiazol-3-one; Skane M 8; 2-n-Octyl-3-isothiazolone; 2-n-Octyl-4-isothiazolin-3-one; 2-Octyl-3-isothiazolinone; 2-Octyl-3-isothiazolone; 2-Octyl-3-isothioazolone; 2-Octyl-3(2H)-isothiazolone; 2-Octyl-4-isothiazolin-3-one; Kathon 893; Kathon sp 70; Micro-Chek 11; Micro-chek 11D; Micro-chek skane; Microbicide M-8; Octhilinone; Octyl-3(2H)-isothiazolone; Pancil; Pancil T; RH-893; Skane 8; Kathon 4200; Kathon 893F; Kathon LM; Vinyzene IT 3000DIDP; 2-octyl-2H-isothiazol-3-one

Properties
The active content of the 2-Octyl-2H-Isothiazol-3-one (OIT) is 45% or 95%. The specific gravity of the OIT biocide is 1.03~1.04.

2-Octyl-2H-Isothiazol-3-one is a low toxicity biocide. 
It is specifically developed for the complete microbiological protection of water-based and solvent-based products against bacterial and fungal spoilage in the wet state.

Applications
This octylisothiazolinone is effective against mildew, bacteria, and fungi. It is widely used in a variety of industrial applications. 
Such as water treatment, paper pulp, coating & painting, metal cutting fluid, personal care products, cosmetics, etc.

Package and Storage
OIT biocide is packed in 25kg or 200kg plastic drum, or 1000kg IBC.

Synonyms
Octylisothiazolinone, 2-n-Octyl-4-Isothiazolin-3-One, OIT, n-Octyl-4-Isothiazolin-3-One, NOIT, mildewcide OIT.

Synonym:2-octyl-3(2h)-isothiazolon;2-octyl-3-isothiazolone;2-octyl-4-isothiazolin-3-on

CAS No.:26530-20-1

EINECS No.:247-761-7

Molecular Formula:C11H19NOS

Molecular Weight:213.3397

Properties:It is a light yellow to amber transparent liquid. Soluble in organic solvents and slightly soluble in water. Boiling point: 120℃, Density: 1.04, Refractive index: 1.5500.

Uses:It is a low toxicity, high efficiency, broad-spectrum antifungal agent, has a strong killing effect on mould, can achieve the ideal antifungal effect. 
It can be widely used in coatings, paints, lubricants, shoe oils, leather chemistry, wood products and cultural relics protection and many other products. 
VOC-free, stable under strong light and high temperature, broad-spectrum and efficient sterilization, can effectively prevent bacteria and fungi in plastics.

Storage:Sealed and stored in a cool, dry and ventilated place.

Packing:200kg plastic barrel


2-octyl-2H-isothiazol-3-one
2-octyl-2H-isothiazol-3-one
2-octyl-2H-isothiazol-3-one (OIT)
Octhilinone
octhilinone (ISO)
octhilinone (ISO); 2-octyl-2H-isothiazol-3-one
octhilinone (ISO); 2-octyl-2H-isothiazol-3-one; [OIT]
octhilinone (ISO);2-octyl-2H-isothiazol-3-one
octhilinone (ISO);2-octyl-2H-isothiazol-3-one; [OIT]

Translated names
2-Octil-2H-isotiazol-3-ona (OIT) (es)
2-Octil-2H-isotiazol-3-ona (OIT) (pt)
2-octil-2H-isotiazol-3-onă (OIT) (ro)
2-octyl-2H-isothiazol-3-on (OIT) (da)
2-Octyl-2H-isothiazol-3-on (OIT) (de)
2-octyl-2H-isothiazol-3-one (OIT) (mt)
2-octyl-2H-isothiazol-3-one (OIT) (no)
2-octyl-2H-isothiazole-3-one (OIT) (fr)
2-Octyl-2H-isothiazool-3-on (OIT) (nl)
2-oktil-2H-izotiazol-3-on (OIT) (hr)
2-oktil-2H-izotiazol-3-on (OIT) (hu)
2-oktil-2H-izotiazol-3-on (OIT) (sl)
2-oktil-2H-izotiazol-3-onas (OIT) (lt)
2-Oktil-2H-izotiazol-3-ons (OIT) (lv)
2-oktyl-2H-isotiazol-3-on (no)
2-oktyl-2H-isotiazol-3-on (OIT) (sv)
2-oktyl-2H-izotiazol-3-ón (OIT) (sk)
2-oktylo-2H-izotiazol-3-on (OIT) (pl)
2-oktyltetrahydroisothiazol-3-on (OIT) (cs)
2-oktyyli-2H-isotiatsol-3-oni (OIT) (fi)
2-oktüül-2H-isotiasool-3-oon (OIT) (et)
2-ottil-2H-isotiazol-3-one (OIT) (it)
2-οκτυλ-2H-ισοθειαζολόνη-3 (OIT) (el)
2-октил-2H-изотиазол-3-он (OIT) (bg)
octhilinon (ISO); 2-octyl-2H-isothiazol-3-on; [OIT] (da)
Octhilinon (ISO); 2-Octyl-2H-isothiazol-3-on; [OIT] (de)
octhilinone (ISO); 2-octyl-2H-isothiazol-3-one; [OIT] (fr)
octhilinone (ISO); 2-octyl-2H-isothiazool-3-on; [OIT] (nl)
octhilinone (οκθειλινόνη) (ISO)· 2-οκτυλ-2H-ισοθειαζολόνη-3 [OIT] (el)
Octilinona (ISO); 2-octil-2H-isotiazol-3-ona; [OIT] (es)
octilinona (ISO); 2-octil-2H-isotiazol-3-ona; [OIT] (pt)
octilinone (ISO); 2-ottil-2H-isotiazol-3-one; [OIT] (it)
octilinonă (ISO); 2-octil-2H-izotiazol-3-onă; [OIT] (ro)
okthilinon (ISO); 2-oktyl-2H-isothiazol-3-on; [OIT] (cs)
oktilinon (ISO); 2-oktil-2H-isotijażol-3-on; [OIT] (mt)
oktilinon (ISO); 2-oktil-2H-izotiazol-3-on; [OIT] (hr)
oktilinon (ISO); 2-oktil-2H-izotiazol-3-on; [OIT] (hu)
oktilinon (ISO); 2-oktil-2H-izotiazol-3-on; [OIT] (sl)
oktilinon (ISO); 2-oktyl-2H-isotiazol-3-on; [OIT] (sv)
oktilinonas (ISO); 2-oktil-2H-izotiazol-3-onas; [OIT] (lt)
oktilinoni (ISO); 2-oktyyli-2H-isotiatsol-3-oni; [OIT] (fi)
oktilinons (ISO); 2-oktil-2H-izotiazol-3-ons; [OIT] (lv)
Oktilinoon (ISO); 2-oktüül-2H-isotiasool-3-oon; [OIT] (et)
oktilinón (ISO); 2-oktyl-2H-izotiazol-3-ón; [OIT] (sk)
oktylinon (ISO); 2-oktylo-2H-izotiazol-3-on; [OIT] (pl)
октилинон (ISO); 2-октил-2H-изотиазол-3-он; [OIT] (bg)

CAS names
3(2H)-Isothiazolone, 2-octyl-

IUPAC names
2-N-Octyl-4-isothiazolin-3-on
2-n-Octyl-4-isothiazolin-3-one
2-n-Octyl-4-isothiazolinone-3-one
2-octil-2H-isotiazol-3-ona
2-octyl-1,2-thiazol-3-one
2-octyl-2,3-dihydro-1,2-thiazol-3-one
2-octyl-2,3-dihydro-1,2-thiazol-3-one
2-Octyl-2H-isothiazol-3-one
2-octyl-2H-isothiazol-3-one
2-octyl-2h-isothiazol-3-one
2-octylisothiazol-3(2H)-one
octhilinone (ISO)
Octylisothiazolinone

Other identifiers
1135442-68-0

CAS number
1135442-68-0

Deleted CAS number
122667-23-6

CAS number
122667-23-6

Deleted CAS number
12673-72-2

CAS number
12673-72-2

Deleted CAS number
1617530-25-2

CAS number
1617530-25-2

Deleted CAS number
245125-70-6

CAS number
245125-70-6

Deleted CAS number
249757-59-3

CAS number
249757-59-3

Deleted CAS number
26530-20-1

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