POLOXAMER 184

Poloxamer 184 is used in the cosmetic industry primarily as a cleansing agent.
Poloxamer 184 is also a great emulsifier that aids in the mixing of the ingredients properly and binds them together.
Poloxamer 184 is a synthetic polymer that is used in a range of products such as shampoos, mouthwashes and eye makeup removers.

CAS Number: 9003-11-6
Molecular Formula: C5H10O2
Molecular Weight (g/mol): 102.13

Some other names of Poloxamer 184 are Kolliphor, Synperonic and Pluronic.
Additionally, the chemical formula of Poloxamer 184 is C5H10O2.

INCI: Poloxamer184

What is Poloxamer184?
Poloxamer 184 is a copolymer with a central oil-loving chain of polyoxypropylene and two side water-loving chains of polyoxyehtylene.
The word poloxamer was first coined by its inventor Irving Schmolka.

There are many different types of poloxamers.
Poloxamer 184 dissolves in water and forms a gel. It has a special and unique characteristic of temperature-dependent gelling behavior.
At low temperatures they are liquid and at higher temperatures, they become a gel.

Use & Benefits of Poloxamer 184:
Poloxamer184 is used in cosmetic products as a surfactant, cleansing agent, and also as a solvent to solubilize different ingredients.
As a surfactant Poloxamer 184 lowers the surface tension between two components of the product like two liquids or a liquid and a solid.

So, there is more room for ingredients in the solvent plus it helps create foams in the solution/ suspension.
As a cleansing agent, as mentioned earlier, it attracts dirt, oil, and other impurities accumulated on the surface of the skin from its oil-loving part and the water-loving part that can be washed off easily with water.

Poloxamer 184 has various groups in its chemical structure, these groups help mingle the chemical groups of other ingredients very well, without creating any chemical upsets in the system.
Poloxamer 184 is mild on the eyes and skin.
Poloxamer 184 finds its use in recipes of cleaning products, bath products, and other personal care products.

Poloxamer 184, Surfactant is a nonionic triblock copolymer.
Poloxamer 184 is made up of a main hydrophobic chain of polyoxypropylene bordered on each side by two hydrophilic chains of polyoxyethylene.
Ungraded products are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.

Functions of Poloxamer 184:
Dispersing agents
Foaming and foam control agents
Solubilisers
Surfactants / detergents

Applications of Poloxamer 184:
Bath, shower & soaps
Eye contour care
Facial cleansers
Hair conditioners - rinse off

What is Poloxamer 184 used for?
Poloxamer 184 serves important functions in the formulations of cosmetic, skin and hair care products.

Skin care:
Poloxamer 184 is a great surfactant/cleanser that is mild on the skin and does not have any harsh effects.
Poloxamer 184 also aids other ingredients in mixing well together and thus keeps the formulations from falling apart.

Poloxamer 184 reduces the tension of the cosmetic products and helps them to spread evenly.
Poloxamer 184 is also gentle on the skin and does not weigh it down.

Hair care:
Poloxamer 184 helps water and oil to mix and thus acts as a great cleanser for the hair.
Poloxamer 184 aids the mixing of dirt and oil with water so that they can be washed away easily, leaving the hair clean.

Origin:
Poloxamer 184 is a synthetic polymer and a nonionic surfactant that is made up of a hydrophobic chain of polyoxypropylene.
This polyoxypropylene has two hydrophilic chains of polyoxyehtylene on each side.

What does Poloxamer 184 do in a formulation?
Cleansing
Emulsifying
Oral care
Surfactant

CAS Number: 9003-11-6
Chem/IUPAC Name: Oxirane, methyl-, polymer with oxirane (13;30)
COSING REF No: 80133

Poloxamer 184 is a great emulsifier that aids in the mixing of the ingredients properly and binds them together.

KEYWORDS:
9003-11-6, 106392-12-5, Poloxamer, Oxirane methyl- polymer with oxirane (13;30), 2-methyloxirane; oxirane, Poloxamer 188, Poloxamer 124, Poloxamer 407, Poloxamer 188 NF, Antarox P 407

Poloxamer 184 is a block copolymer of ethylene glycol and propylene glycol that is used as an emulsifier in a wide variety of areas from cosmetics to oral care products.
Poloxamer 184 has a cloud point of 58-62°C, an average molecular weight of approx. 2,900, and a viscosity of approx. 850 mPas.

Poloxamer 184 is anhydrous and non-corrosive.
Therefore, mild steel can be used for storage tanks, piping and conventional process equipment.

Safety Profile of Poloxamer 184:
Poloxamer 184 is safe for hair and skin as it is gentle and light without having any harmful side effects.
However, a patch test is recommended for people with highly sensitive skin.

Moreover, precautions should be taken to not ingest products with Poloxamer 184 accidentally, otherwise, it may be toxic.
Poloxamer 184 is largely non-comedogenic however it may cause acne on certain skin types.

A synthetic polymer (a big molecule made of repeated units) that's used as a mild cleansing agent.
Poloxamer 184 is also used in contact lens solutions and a regular on the ingredient lists of micellar cleansing waters.

Chemically speaking, Poloxamer 184 is an interesting molecule with an oil-loving part in the middle surrounded by two water-loving parts.
The numbers in the molecule refer to the overall molecular size and the water-loving part in it (40%).
Poloxamer 184 is almost half-half oil and water-soluble, likes to form micelles (molecules gathered into a ball form with oil-loving parts inside and water-loving parts outside) and is claimed to be an effective cleansing agent that is also mild on the skin and the eyes.

What Is Poloxamer 184?
Poloxamers (Poloxamer 101, Poloxamer 105, Poloxamer 108, Poloxamer 122, Poloxamer 123, Poloxamer 124, Poloxamer 181, Poloxamer 182, Poloxamer 183, Poloxamer 184, Poloxamer 185, Poloxamer 188, Poloxamer 212, Poloxamer 215, Poloxamer 217, Poloxamer 231, Poloxamer 234, Poloxamer 235, Poloxamer 237, Poloxamer 238, Poloxamer 282, Poloxamer 284, Poloxamer 288, Poloxamer 331, Poloxamer 333, Poloxamer 334, Poloxamer 335, Poloxamer 338, Poloxamer 401, Poloxamer 402, Poloxamer 403, Poloxamer 407, Poloxamer 105 Benzoate, Poloxamer 182 Dibenzoate) are polymers made of a block of polyoxyethylene, followed by a block of polyoxypropylene, followed by a block of polyoxyethylene.
The average number of units of polyoxyethylene and polyoxypropylene varies based on the number associated with the polymer.

For example, the smallest polymer, Poloxamer 101, consists of a block with an average of 2 units of polyoxyethylene, a block with an average of 16 units of polyoxypropylene, followed by a block with an average of 2 units of polyoxyethylene.
Poloxamers range from colorless liquids and pastes to white solids.
In cosmetics and personal care products, Poloxamers are used in the formulation of skin cleansers, bath products, shampoos, hair conditioners, mouthwashes, eye makeup remover and other skin and hair products.

Why is Poloxamer 184 used in cosmetics and personal care products?
Poloxamers help to form emulsions by reducing the surface tension of the substances to be emulsified and help other ingredients to dissolve in a solvent in which they would not normally dissolve.
They also clean the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away.

Poloxamer 188 kills microorganisms, or prevents or inhibits their growth and reproduction.
Poloxamer 182 Dibenzoate acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance.

Scientific Facts about Poloxamer 184:
Many Poloxamers dissolve in water and form gels.
These gels revert to liquid when the temperature is lowered and then reform as gels when the temperature is increased.

Poloxamer 184 is a High-HLB emulsiier used in cleansing water formulas.
They are suitable for use in conjunction with Poloxamer 124 To increase the efficiency of wiping off makeup from the skin

Poloxamer 184 does not irritate the eyes.
Therefore can be used in the formula to wipe makeup around the eyes

The company sells 4 types of Poloxamer.
Poloxamer 124:
Poloxamer 124 is used to wash cosmetics

Poloxamer 184:
Poloxamer 184 is used to wash cosmetics

Poloxamer 188:
Poloxamer 188 is commonly used in cleaning products that do not need to be washed off, commonly used for removing makeup.

Poloxamer 407:
Poloxamer 407 powder It is commonly used as a solvent, perfume and oil in water formulations.
Poloxamer 407, flake type It is commonly used as a solvent, perfume and oil in water formulations.

CAS:
9003-11-6

Molecular Formula:
C5H10O2

Molecular Weight (g/mol):
102.13

InChI Key:
RVGRUAULSDPKGF-UHFFFAOYNA-N

IUPAC Name:
2-methyloxirane; oxirane

SMILES:
C1CO1.CC1CO1

Usage:
For any recipe Acts as an emulsifier.

Mixing method:
Mix in water

Rate of use:
0.1-10.0%

Product characteristics:
Light yellow clear liquid

Solubility of Poloxamer 184:
Poloxamer 184 can dissolve in water, alcohol

Storage of Poloxamer 184:
Poloxamer 184 can be stored at room temperature Covered from sunlight, heat, the product is at least 2 years old.

INCI Name :
Poloxamer 184

Specifications of Poloxamer 184:
pH: 5.0 to 7.5
CAS Max %: 1
Quantity: 500 mL
Grade: Reagent
Packaging: Amber Glass Bottle
Water: 0.004

Substance information:
Poloxamers are block copolymers composed of ethylene oxide and propylene oxide.
With the suffixed number the mass percentages of the two components as well as the overall molecular mass are encoded.

Background information on use in cosmetics
Surfactants are so-called detergent substances and have a major significance in cosmetics for the cleansing of the skin and hair.
Surfactants are substances which, based on their molecular structure, are able to reduce the surface tension of a liquid.

In this way it is possible that two actually not mixable substances, such as oil and water, can be finely mixed.
Because of their properties, surfactants have manifold uses in cosmetics: they can cleanse, produce foam and act as emulsifiers and mix substances with one another.
In shampoos, shower gels and soaps, surfactants are, for instance, used to wash fat and soil particles with water off from the body.

Surfactants are also used in toothpaste.
Here they promote during tooth cleaning the rapid and full dissolution and distribution of the paste in the mouth.

The surfactants used in cosmetic products are primarily produced synthetically on the basis of vegetable raw materials.
Surfactants are often used in combination to equally meet all desired requirements – like dissolution of soil and formation of foam in combination with a good skin tolerance – in the best possible manner.
Through a skilled combination of a surfactant – viewed on its own – with unfavourable skin tolerance but a very good soil removal property with a very mild, skin protecting surfactant altogether a product with good cleansing properties and the same good skin tolerances is obtained.

Emulsifiers are often used in cosmetics as excipients.
They allow actually unmixable components like oil and water to be brought in a permanently stable emulsion.

In this way both aqueous and oily care and active ingredients can be used in one and the same product in cosmetics.
Emulsifiers are able to do that since their molecules consist of a lipophilic and a hydrophilic part.

In this way they can reduce the interfacial tension which actually exists between two incompatible substances like fat and water.
Emulsifiers are, more particularly, used for creams, lotions and cleansing agents.

At present emulsifiers are, however, more than only excipients which keep an emulsion stable.
Fatty acid esters on the basis of sugar, lecithin or glycerin monodistearate contribute, for instance, to improving the moisture balance of the skin and are, therefore, also considered as cosmetic active ingredients.

Regulatory process names:
Oxirane, 2-methyl-, polymer with oxirane, block
Poloxamer
poloxamer 407

IUPAC names:
Poloxamer 407

Other names:
Oxirane, 2-methyl-, polymer with oxirane, block

Other identifiers:
106392-12-5