POLYGLYKOL 8000 = PEG 8000
CAS Number: 25322-68-3
EC Number: 500-038-2
Formula: H(OCH2CH2)nOH
n = about 181
Properties of Polyglykol 8000:
Polyglykol 8000 is a white waxy solid at room temperature.
Polyglykol 8000 FL can be supplied in heated tank trucks.
Polyglykol 8000 S is a flaked type, Polyglykol 8000 P and 8000 PF are powdered types available.
Polyglykol 8000s two hydroxy end groups as well as its ether groups mainly control the physical and chemical properties of Polyglykol 8000.
Polyglykol 8000 is soluble in water and polar organic solvents like aceton or methanol.
Polyglykol 8000 is insoluble in pure hydrocarbons.
Polyglykol 8000 displays typical chemical reactions of alcohols/diols.
The solidification point, of Polyglykol 8000 is about 58°C.
Polyethylene Glycol (PEG) 8000 is PEG-180-based mold release agent and plasticizer.
Polyglykol 8000 possesses lubricity and humectant properties.
Polyglykol 8000 maintains wet-tack strength.
Polyglykol 8000 is used in pressure sensitive and thermoplastic adhesives.
Polyethylene Glycol (PEG) 8000 meets the requirements for use under food additive regulations for indirect use as components of articles intended for use in contact with food.
Advantages of Polyglykol 8000:
-excellent plasticizer and anti-adhesion agent,
-softening, lubricating, moisturizing and thickening properties,
-binder – also in detergents,
-safe, non-toxic substance, does not cause skin irritation,
-unlimited solubility in water,
-biodegradable product,
-product not classified in accordance with the CLP / GHS Regulation
Applications of Polyglykol 8000:
-cosmetics,
-detergents in the form of tablets,
-production of packaging,
-metalworking,
-construction industry,
-textile industry,
-processing of plastics and elastomers,
-production of ceramics.
Storage of Polyglykol 8000:
When stored in a cold, dry place in a closed container Polyglykol 8000 S, 8000 P and 8000 PF can be kept for at least two years.
Applications of Polyglykol 8000:
Based on their physical and chemical characteristics -polyethylene glycols are used for a wide variety of applications.
Polyglykol 8000 P is a polethylene glycol with a mean molecular weight of 8000.
Polyglykol 8000 is a solid in powder form.
Benefits of Polyglykol 8000:
-Good solubility in water
-Very low water content
-Compatible with hard water
-Non-volatile
-Outstanding toxicological safety
Fields of applications of Polyglykol 8000:
- Reactive diol/polyether component in polyester or polyurethene resins
- Component of auxiliaries for leather and textile proc[1]essing
- Cosmetic / pharmaceutical formulations (e.g. humec[1]tant or plasticiser for creams, tablets, tooth paste)
- Lubricant and mould release agent for rubber, plastic and elastomer processing
- Plasticizer and binder for ceramic and concrete manufacturing
- Component of lubricant formulations
- Water soluble, lubricating component in metalwork[1]ing fluids
- Humectant for paper, wood and cellulose films
- Solvent and humectant for dyes and inks
- Modifier for production of regenerated viscose
- Humectant and plasticizer for adhesives
Polyglykol 8000 is available in the form of white to light yellow wax.
KEYWORDS:
25322-68-3, 500-038-2, PEG 8000, Polyglykol 8000 S, Polyglykol 8000 P, Polyglykol 8000 FL, Polyglykol 8000 PF, Glycol polyethylene, Miralax, Polyethylene oxide
Polyglykol 8000 flakes is a product belonging to the group of polyoxyethylene glycols (PEG with an average molecular weight of 8000), INCI name: PEG-180.
Polyglykol 8000 is available in the form of white to light yellow wax.
The flake form is a great convenience for formulators due to the ease of dosing, storage of the product and the lack of financial outlays related to heating.
The solidification point of the product is approximately 55 °C.
Polyglykol 8000 dissolves freely in water and in low aliphatic alcohols.
Polyglykol 8000 is safe, non-toxic and does not cause skin irritation.
Polyglykol 8000 flakes can be used as a humectant in cosmetic preparations such as conditioners, serums, shampoos and hair masks, hair styling preparations.
Polyglykol 8000 is a thickening agent for shampoos, body wash liquids or foam baths.
Polyglykol 8000 is easy to dose and has the ability to modify the viscosity of the formulation, even at low concentrations.
Polyglykol 8000 can also be used as a carrier of active substances and a binder in dishwasher tablets, laundry tablets and bath salts.
In industrial applications Polyglykol 8000 is a component of lubricants, mainly water-soluble synthetic liquids for machining and heat transfer fluids.
Polyglykol 8000 is used as a release agent in the rubber processing industry (tire production), plastics and elastomers.
Polyglykol 8000 is also used as an auxiliary agent during galvanizing processes.
Polyglykol 8000 is also an auxiliary for the processing of textiles and in paint additives.
Polyglykol 8000 flakes acts as a plasticizer and binding agent in the production of ceramics and food packaging based on biopolymers.
Polyglykol 8000 should be noted that the product may be used in accordance with the definitions provided by the organization, not exceeding the maximum permitted dose.
These characteristics are guidance only and not be taken as product specifications.
The tolerances are given in the product specification sheet.
colour index [APHA] (EN 1557) (25 % in water): max. 30
pH (5 % w/w in water) (DIN EN 1262): 5 – 7
hydroxyl number (DIN 53240) mg KOH/g : 12 – 16
molecular weight g/mol: 7300 – 9000
solidification point (EP III) °C: 55 – 60
viscosity at 20°C (50 % w/w in water) (DIN 51562) mPas: 290 – 450
flash point (DIN 51376) °C: 255
ignition temperature (DIN 51794) °C : >320
ethylene oxide: ppm max. 1
dioxane: ppm max. 1
polyethylene glycol 8000 (CAS No. 25322-68-3) is a polyethylene glycol having white to off white color and available in solid flakes or powder form.
polyethylene glycol 8000 used as a base in the formulation of soap sticks.
PEG 8000 has low glycol content and higher crystalinity.
Polyglykol 8000s high molecular weight mainly prompts its use in pharmaceutical formulations as solvent for oral, topical and parenteral preparations.
The high molecular weight PEG 8000 is soluble in water and organic solvents such as alcohols.
Polyglykol 8000 can blend with other PEG molecular weights to achieve the desired viscosity properties. polyethylene glycol 8000 is quite stable and does not support microbial growth, even in aqueous solutions.
What is Polyglykol 8000?
Polyethylene glycol, referred to as PEG, is used as an inactive ingredient in the pharmaceutical industry as a solvent, plasticizer, surfactant, ointments and suppository base, and tablet and capsule lubricant.
PEG has low toxicity with systemic absorption less than 0.5%.
PEGylation occurs when PEGs are attached to various protein medications, allowing for greater solubility for certain drugs.
Examples of PEGylated medications include PEG-interferon alpha (Pegintron) and PEG-filgrastim (Neulasta).
PEG is also available as a bowel prep for colonoscopy procedures and as a laxative.
PEG 400 indicates the average molecular weight of the specific PEG at 400.
PEG 3350 is a laxative available over-the-counter by the name of Miralax.
In this case, PEG is considered an "active" ingredient, even though systemic absorption is less than 0.5%.
This information is based on our present state of knowledge and is intended to provide general notes on our products and their uses.
It should not therefore be construed as guaranteeing specific properties of the products described or their suitability for a particular application.
Any existing industrial property rights must be observed.
Composition: Polyethylene glycol
INCI-designation: PEG-180
Synonyms: PEG, Poly(ethylene glycol)
Alternate Names: PEG 8000 Powder is also known as Polyethylene glycol 8000.
Application: PEG 8000 Powder is a compound used to modify therapeutic proteins and peptides to increase their solubility.
Polyethylene Glycol 8000 (PEG 8000) is a safe solvent and carrier for cosmetic use.
Polyglykol 8000 can act as a solvent in many substances.
Polyglykol 8000 is also a safe carrier.
Uses of Polyglykol 8000:
Medical uses of Polyglykol 8000:
PEG used in medicines for treating disimpaction and maintenance therapy for children with constipation.
When attached to various protein medications or drug carriers, polyethylene glycol of suitable length slows down their clearance from the blood.
The possibility that PEG could be used to fuse axons is being explored by researchers studying peripheral nerve and spinal cord injury.
An example of PEG hydrogels (see Biological uses section) in a therapeutic has been theorized by Ma et al.
They propose using the hydrogel to address periodontitis (gum disease) by encapsulating stem cells in the gel that promote healing in the gums.
The gel and encapsulated stem cells was to be injected to the site of disease and crosslinked to create the microenvironment required for the stem cells to function.
PEGylation of adenoviruses for gene therapy can help prevent adverse reactions due to pre-existing adenovirus immunity.
Chemical uses of Polyglykol 8000:
Because PEG is a hydrophilic molecule, it has been used to passivate microscope glass slides for avoiding non-specific sticking of proteins in single-molecule fluorescence studies.
Polyethylene glycol has a low toxicity and is used in a variety of products.
The polymer is used as a lubricating coating for various surfaces in aqueous and non-aqueous environments.
Since PEG is a flexible, water-soluble polymer, it can be used to create very high osmotic pressures (on the order of tens of atmospheres).
It also is unlikely to have specific interactions with biological chemicals.
These properties make PEG one of the most useful molecules for applying osmotic pressure in biochemistry and biomembranes experiments, in particular when using the osmotic stress technique.
Polyethylene glycol is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers.
Biological uses of Polyglykol 8000:
PEG can be modified and crosslinked into a hydrogel and used to mimic the extracellular matrix (ECM) environment for cell encapsulation and studies.
An example study was done using PEG-diacrylate hydrogels to recreate vascular environments with the encapsulation of endothelial cells and macrophages.
This model furthered vascular disease modeling and isolated macrophage phenotype's effect on blood vessels.
PEG is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions.
In blood banking, PEG is used as a potentiator to enhance detection of antigens and antibodies.
When working with phenol in a laboratory situation, PEG 300 can be used on phenol skin burns to deactivate any residual phenol.
In biophysics, polyethylene glycols are the molecules of choice for the functioning ion channels diameter studies, because in aqueous solutions they have a spherical shape and can block ion channel conductance.
PEG has been used as the gate insulator in an electric double-layer transistor to induce superconductivity in an insulator.
PEG is also used as a polymer host for solid polymer electrolytes.
Although not yet in commercial production, many groups around the globe are engaged in research on solid polymer electrolytes involving PEG, with the aim of improving their properties, and in permitting their use in batteries, electro-chromic display systems, and other products in the future.
PEG is injected into industrial processes to reduce foaming in separation equipment.
PEG is used as a binder in the preparation of technical ceramics.
PEG was used as an additive to silver halide photographic emulsions.
Entertainment uses of Polyglykol 8000:
PEG is used to extend the size and durability of very large soap bubbles.
PEG is the main ingredient in many personal lubricants. (Not to be confused with propylene glycol.)
PEG is the main ingredient in the paint (known as "fill") in paintballs.
Molecule Weight 8000
Usage: Can be used as a solvent or as a carrier in all kinds of cosmetics.
Mixing method: Mixed with the substance to be dissolved
Rate of use: Depending on use
Product characteristics: Flakes or white powder
Solubility: Soluble in water, ethanol, glycols (eg propylene glycol, butylene glycol).
Storage: Can be stored at room temperature But close the bottle tightly And sealed from direct sunlight or heat, the product is at least 2 years old
CAS Number: 25322-68-3
Grade: Technical
Appearance: solid
Application Type: Personal care
Boiling Point: > 200 °C (> 392 °F)
Color: white
Flash Point: 177 - 246 °C (351 - 475 °F)
Melting Point: 37 - 63 °C (99 - 145 °F)
Odor: odorless, mild
Recommended Use: in Personal Care
Relative Density: 1.113 @ 50 - 60 °C (122 - 140 °F) Reference Material: (water = 1)
Relative Vapor Density: > 10
Solubility in Water: soluble
Vapor Pressure: < 0.1 mmHg @ 20 °C (68 °F)
Polyglykol 8000 S
Polyglykol 8000 P
Polyglykol 8000 FL
Polyglykol 8000 PF
Glycol, polyethylene
Miralax
Polyethylene oxide
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CAS Number
25322-68-3
CAS No: 25322-68-3
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