Trisodium citrate dihydrate is produced by complete neutralization of citric acid with high purity sodium source (sodium hydroxide or sodium carbonate) and subsequent crystallization.
Trisodium citrate dihydrate is considered “GRAS” (Generally Recognized As Safe) by the United States Food and Drug Administration without restriction as to the quantity of use within good manufacturing practice.
Trisodium citrate dihydrate is available as translucent white crystals and has a slight saline taste.
CAS Number: 6132-04-3
EC Number 200-675-3
Molecular Formula: C6H5Na3O7.2H2O
Exact Mass: 293.99396471
Synonyms: Trisodium citrate dihydrate, Sodium citrate dihydrate, 6132-04-3, Sodium citrate tribasic dihydrate, Sodium citrate hydrate, 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrate, Citric acid trisodium salt dihydrate, trisodium;2-hydroxypropane-1,2,3-tricarboxylate;dihydrate, MFCD00150031, trisodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate, SODIUM CITRATE, DIHYDRATE, B22547B95K, Citric acid, trisodium salt, dihydrate, Sodium citrate hydrous, Trisodium citrate dihydrate;Citric acid trisodium salt dihydrate, MFCD00130806, tri-sodium citrate dihydrate, sodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate, Sodiumcitrate, N-1560, Natrum citricum, Tricitrasol (TN), Sodium citrate (TN), Sodium citrate [USP:JAN], Sodiumcitratetribasicdihydrate, SODIUM CITRATE [FHFI], DTXSID1049437, Sodium citrate hydrate (JP17), UNII-B22547B95K, CHEBI:32142, Trisodium citrate dihydrate, ACS, SODIUM CITRATE HYDROUS [II], SODIUM CITRATE HYDRATE [JAN], SODIUM CITRATE [EP MONOGRAPH], SODIUM CITRATE DIHYDRATE [MI], AKOS025293920, Citronensaeure,Trinatrium-Salz-Dihydrat, Sodium citrate dihydrate, >=99%, FG, SODIUM CITRATE DIHYDRATE [VANDF], Trisodium citrate dihydrate [II], BP-31019, SODIUM CITRATE DIHYDRATE [WHO-DD], Sodium citrate tribasic dihydrate, >=98%, Sodium citrate dihydrate, ACS reagent grade, SODIUM CITRATE, DIHYDRATE [WHO-IP], D01781, F82065, Sodium citrate tribasic dihydrate, AR, >=99%, Sodium citrate tribasic dihydrate, LR, >=99%, Citric acid trisodium salt dihydrate ACS reagent, NATRII CITRAS, DEHYDRATE [WHO-IP LATIN], A833161, A835986, Trisodium citrate dihydrate [USP MONOGRAPH], Q22075862, Sodium citrate dihydrate Biochemical grade, Fine Granular, Sodium citrate tribasic dihydrate, USP, 99.0-100.5%, Sodium Citrate Tribasic Dihydrate (Molecular Biology Grade), Sodium citrate tribasic dihydrate, ACS reagent, >=99.0%, trisodium 2-oxidanylpropane-1,2,3-tricarboxylate dihydrate, Citric acid trisodium salt dihydrateTrisodium citrate dihydrate, Sodium citrate tribasic dihydrate, BioUltra, >=99.0% (NT), Sodium citrate tribasic dihydrate, insect cell culture tested, Sodium citrate tribasic dihydrate, JIS special grade, >=99.0%, Sodium citrate tribasic dihydrate, p.a., ACS reagent, 99.0%, Sodium citrate tribasic dihydrate, purum p.a., >=99.0% (NT), Sodium citrate tribasic dihydrate, SAJ first grade, >=99.0%, Sodium citrate tribasic dihydrate, tested according to Ph.Eur., trisodium 2-hydroxypropane-1,2,3-tricarboxylate--water (1/2), Trisodium citrate dihydrate, meets USP testing specifications, 2-hydroxy-1,2,3-propanetricarboxylic acid trisodium salt dihydrate, Sodium citrate tribasic dihydrate, BioXtra, >=99.0% (titration), Sodium citrate tribasic dihydrate, for molecular biology, >=99%, Sodium citrate tribasic dihydrate, Vetec(TM) reagent grade, 98%, Sodium citrate, United States Pharmacopeia (USP) Reference Standard, 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt, dihydrate, Sodium citrate tribasic dihydrate, p.a., ACS reagent, reag. ISO, 99-101%, 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt, hydrate (1:3:2), Sodium citrate tribasic dihydrate, BioUltra, for molecular biology, >=99.5% (NT), Sodium citrate tribasic dihydrate, puriss. p.a., ACS reagent, >=99.0% (NT), Sodium citrate tribasic dihydrate, suitable for amino acid analysis, >=99.0%, Sodium Citrate, Pharmaceutical Secondary Standard; Certified Reference Material, Sodium citrate tribasic dihydrate, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., >=99.5%, Sodium citrate tribasic dihydrate, suitable for amino acid analysis, >=98% (titration), powder, Sodium Citrate, Dihydrate, Citric acid trisodium salt dihydrate, Sodium Citrate Dihydrate, Sodium citrate tribasic dihydrate, Trisodium citrate, Sodium citrate dihydrate, Citric acid tridosium salt dihydrate, Trisodium citrate, dihydrate, Citric acid, Trisodium Salt, Dihydrate,, Sodium citrate dihydrate, Sodium citrate tribasic dihydrate, 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrate, 2-hydroxy-1,2,3-propanetricarboxylic acid trisodium salt dihydrate, Sodium citrate hydrate, Trisodium citrate dihydrate, Sodium citrate dihydrate, Sodium citrate tribasic dihydrate, Citric acid trisodium salt dihydrate, Trisodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate, 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrate, CITRIC ACID MONO, SODIUM CITRATE TRIBASIC DIHYDRATE, TRI-SODIUM CITRATE DIHYDRATE, SodiuM Citrate (AS), NATRII CITRAS, SODIUM CITRATE, DIHYDRATE, ACIDUM CITRICUM MONOHYDRICUM, CITRIC ACID TRISODIUM SALT DIHYDRATE, BETA-HYDROXY-TRICARBOXYLIC ACID MONOHYDRATE, abs9147, 1,2,3-Propanetricarboxylicacid, 2-hydroxy-,trisodiumsalt,dihydrate, ANTI-BABOON IGM, BIOTIN, BETA-HYDROXY-TRICARBOXYLIC ACID MONOHYDRATE, HYDROXYTRICARBALLYLIC ACID MONOHYDRATE, CITRIC ACID NA3-SALT 2H2O, CITRIC ACID H2O, CITRIC ACID TRISODIUM SALT DIHYDRATE, CITRIC ACID, 3NA, DIHYDRATE, 6132-04-3, 1,2,3-PROPANETRICARBOXYLIC ACID, 2-HYDROXY-, TRISODIUM SALT, DIHYDRATE, CITRIC ACID, TRISODIUM SALT, DIHYDRATE, FEMA NO. 3026, N-1560, NATRII CITRAS, DEHYDRATE [WHO-IP LATIN], SODIUM CITRATE [EP MONOGRAPH], SODIUM CITRATE [FHFI], SODIUM CITRATE DIHYDRATE, SODIUM CITRATE DIHYDRATE [MI], SODIUM CITRATE DIHYDRATE [VANDF], SODIUM CITRATE DIHYDRATE [WHO-DD], SODIUM CITRATE HYDRATE, SODIUM CITRATE HYDRATE [JAN], SODIUM CITRATE HYDROUS, SODIUM CITRATE HYDROUS [II], SODIUM CITRATE, DIHYDRATE, SODIUM CITRATE, DIHYDRATE [WHO-IP], Trisodium citrate dihydrate [II], Trisodium citrate dihydrate [USP MONOGRAPH]
Trisodium citrate dihydrate is the dihydrate of trisodium citrate.
Trisodium citrate dihydrate has a role as an anticoagulant.
Trisodium citrate dihydrate contains a sodium citrate.
Trisodium citrate dihydrate is a tribasic salt of citric acid.
Trisodium citrate dihydrate has a sour taste similar to citric acid, and is salty as well.
Trisodium citrate dihydrate is a tribasic salt of citric acid.
Trisodium citrate dihydrate is produced by complete neutralisation of citric acid with high purity sodium hydroxide or carbonate and subsequent crystallisation.
Trisodium citrate dihydrate occurs as white, granular crystals or as white, crystalline powder with a pleasant, salty taste.
Trisodium citrate dihydrate is slightly deliquescent in moist air, freely soluble in water and practically insoluble in ethanol (96 %).
Trisodium citrate dihydrate is a non-toxic, neutral salt with low reactivity.
Trisodium citrate dihydrate is chemically stable if stored at ambient temperatures.
Trisodium citrate dihydrate is fully biodegradable and can be disposed of with regular waste or sewage.
Trisodium citrate dihydrate is available in various granulations.
Trisodium citrate dihydrate is soluble in water.
Trisodium citrate dihydrate is insoluble in alcohol.
Trisodium citrate dihydrate is a tribasic salt of citric acid.
Trisodium citrate dihydrate is produced by complete neutralisation of citric acid with high purity sodium hydroxide or carbonate and subsequent crystallisation.
Trisodium citrate dihydrate is the product of a microbial fermentation using carbohydrate substrates.
Trisodium citrate dihydrate is a chemical compound that is used as a buffer and to maintain the pH of solutions.
Trisodium citrate dihydrate is a tribasic salt of citric acid.
Trisodium citrate dihydrate is free soluble in water, practically insoluble in ethanol(96 percent).
Trisodium citrate dihydrate is a tribasic salt of citric acid.
Trisodium citrate dihydrate is produced by complete neutralization of citric acid with high purity sodium source (sodium hydroxide or sodium carbonate) and subsequent crystallization.
Trisodium citrate dihydrate is manufactured by neutralizing citric acid derived from a submerged fermentation process.
Trisodium citrate dihydrate is considered “GRAS” (Generally Recognized As Safe) by the United States Food and Drug
Administration without restriction as to the quantity of use within good manufacturing practice.
Trisodium citrate dihydrate is also considered by the Experts Committee of the FAO/WHO to be a safe food additive without limitation according to good manufacturing practice.
Trisodium citrate dihydrate is manufactured to meet the monograph specifications of major world codex and pharmacopoeia standards including the USP, FCC, BP, EP, FAO/WHO.
Cargill Trisodium citrate dihydrate is available as translucent white crystals and has a slight saline taste.
Water of crystallization constitutes approximately twelve percent by weight of the dihydrate form.
Citrate is a intermediate in the Trisodium citrate dihydrate cycle and fatty acid synthesis.
Citrate is an allosteric modulator of acetyl-CoA carboxylase, the enzyme that regulates the conversion of acetyl-CoA to malonyl-CoA.
Trisodium citrate dihydrate possesses a saline, mildly tart flavor.
Trisodium citrate dihydrate is a useful reactant in organic synthesis.
Trisodium citrate dihydrate is a tribasic salt of citric acid.
Trisodium citrate dihydrate consists of colourless to white crystals and is practically odourless.
Trisodium citrate dihydrate is a tribasic salt of citric acid.
Trisodium citrate dihydrate is produced by complete neutralisation of citric acid with high purity sodium hydroxide or carbonate and subsequent crystallisation.
Trisodium citrate dihydrate is the product of a microbial fermentation using carbohydrate substrates.
Trisodium citrate dihydrate, (molecular formula: Na3C6H5O7 • 2H2O) has molecular weight of 294.1, is a colorless crystal or white crystalline powder product; Trisodium citrate dihydrate is odorless, salty taste, and cool.
Trisodium citrate dihydrate will lose its crystal water at 150 & deg;C and will be decomposed at even higher temperature.
Trisodium citrate dihydrate also has slight deliquescence in wet air and has weathering property upon hot air.
Trisodium citrate dihydrate is soluble in water and glycerol, but insoluble in alcohol and some other organic solvents.
Trisodium citrate dihydrate is a versatile chemical substance used in a variety of applications in different industries.
In the medical field, Trisodium citrate dihydrate is used as an anticoagulant but it is also an ingredient in many personal care products.
Trisodium citrate dihydrate can be used as Ph adjusting agents and emulsifying enhancers applied to jam, candy, jelly and ice cream; its combination with citric acid has an effect of alleviating tour.
Trisodium citrate dihydrate also has effects on forming complex with metal ions.
Trisodium citrate dihydrate is white powder or colourless crystals.
Trisodium citrate dihydrate is the tribasic dihydrate sodium salt of citric acid.
Trisodium citrate dihydrate is commonly used laboratory reagent.
Uses And Applications of Trisodium citrate dihydrate:
In the cleaning industry Trisodium citrate dihydrate is commonly used because of its excellent cleaning characteristics and its unusual property of being almost neutral yet portraying the characteristics of an acid as in descalers and an alkali as in degreasers.
Cleaning products include laundry powders and detergents, toilet cleaners, hard surface cleaners, carpet cleaners, dish washing liquids, powder and liquid degreasers and pre-soaks.
Trisodium citrate dihydrate is becoming more and more popular now as it is considered environmentally friendly, Trisodium citrate dihydrate substitutes phosphates and is readily biodegradable.
In industry Trisodium citrate dihydrate finds many uses including alkaline degreaser baths, electroplating chemicals for copper and nickel etc, photo chemicals.
Trisodium citrate dihydrate is also used in the paper and pulp industries and the textiles industry.
Trisodium citrate dihydrate is often used as a food preservative, and as a flavoring in the food industry.
In the pharmaceutical industry Trisodium citrate dihydrate is used to control pH.
Trisodium citrate dihydrate may be used as an alkalizing agent, buffering agent, emulsifier, or sequestering agent.
Trisodium citrate dihydrate is widely used in foods, beverages and various technical applications mainly as buffering, sequestering or emulsifying agent.
Trisodium citrate dihydrate, is widely applied in food, beverages and fillers as a buffering, sequestering or an emulsifying agent.
Trisodium citrate dihydrate used as an anticoagulant in blood transfusions, osmotic laxative, functional fluids, solvents cleaning, furnishing care products, laundry dishwashing products and cleaning automobile radiators.
Sodium salts of citric acid are used as buffers and food preservatives.
They are used medically as anticoagulants in stored blood, and for urine alkalization in the prevention of KIDNEY STONES.
Trisodium citrate dihydrate is the dihydrate of trisodium citrate.
Trisodium citrate dihydrate has a role as an anticoagulant.
Trisodium citrate dihydrate is one of compounds responsible for the physiological oxidation of fats, carbohydrates and proteins to carbon dioxide.
Trisodium citrate dihydrate is widely used as an excellent pH regulator and odourless buffering agent for bath and shower gels, creams, styling or decorative products.
Trisodium citrate dihydrate is often used as an acidity regulator in pharmaceutical formulations and food products.
Trisodium citrate dihydrate has been shown to be effective at reducing the matrix effect and increasing the concentration response, which can lead to better analytical results.
Trisodium citrate dihydrate has also been shown to have anti-inflammatory properties, which may be due to its ability to prevent fatty acid production by inhibiting the enzyme lipase.
Trisodium citrate dihydrate is widely used in foods, beverages and various technical applications mainly as buffering, sequestering or emulsifying agent.
Trisodium citrate dihydrate is often used as a food preservative, and as a flavoring in the food industry.
In the pharmaceutical industry Trisodium citrate dihydrate is used to control pH.
Trisodium citrate dihydrate is used to enhance flavour and maintain stability of active ingredients in food and beverages.
In detergent industry, Trisodium citrate dihydrate can replace STPP as a kind of assistant.
Trisodium citrate dihydrate can also be used in fermentation, injection, photography and metal plating.
Trisodium citrate dihydrate is mildly basic and can be used along with citric acid to make biologically compatible buffers.
Trisodium Citrate is a white odorless chemical used as a food additive.
Trisodium citrate dihydrate is typically used as a flavoring agent or as a preservative.
Trisodium citrate dihydrate is used as flavoring agent in carbonated beverages contributing a tart flavor.
Trisodium citrate dihydrate is also found in gelatin mix, ice cream, yogurt, jams, sweets, milk powder, processed cheeses and bratwurst.
Trisodium citrate dihydrate is used as raw material for pharmaceuticals / Food additives.
A biological buffer, Trisodium citrate dihydrate is used for cell culture, in vitro, enzyme assays and some electrophoretic applications at physiological pH.
Trisodium citrate dihydrate is used in toothpastes & dental creams, effervescent denture cleansers, mouth rinses and oral hygiene products.
Trisodium citrate dihydrate is commonly used in various technical and industrial applications mainly as a pH buffering, sequestering or emulsifying agent.
Trisodium citrate dihydrate is also used as a retarder for mortar mixes.
Trisodium citrate dihydrate is effective to retard plaster mixes.
Trisodium citrate dihydrate must be used carefully as adding too much will prevent the plaster curing properly.
Premix the citrate in water first and add to the plaster mix.
Trisodium citrate dihydrate, also known as sodium citrate, is an organic compound that has white to colorless crystals.
Trisodium citrate dihydrate is odourless, with a cool salty taste.
Trisodium citrate dihydrate is easily soluble in water, glycerol, alcohol and other organic solvents.
Trisodium citrate dihydrate is decomposed by overheating, slightly deliviate in humid environment and slightly weathering in hot air.
Trisodium citrate dihydrate is manufactured by neutralizing citric acid derived from a submerged fermentation process.
Trisodium citrate dihydrate is available as translucent white crystals and has a slight saline taste.
Trisodium citrate dihydrate is a tribasic salt of citric acid.
Trisodium citrate dihydrate is produced by complete neutralization of citric acid with high purity sodium source and subsequent crystallization.
Buffers pH and enhances action of methyl parabens.
Trisodium citrate dihydrate, from Junbunzlauer is a buffering, sequestering and emulsifying agent.
Trisodium citrate dihydrate is a tribasic salt of citric acid and appears as a white granular powder that is non-toxic, freely soluble in water and practically insoluble in ethanol.
Due to its versatile nature, Trisodium citrate dihydrate is perfect for many areas, including Food and Beverages, Cosmetics and Industrial applications.
Trisodium citrate dihydrate is widely used in foods, beverages and various technical applications mainly as buffering, sequestering or emulsifying agent.
Trisodium citrate dihydrate has no toxic effect, and has pH adjusting capability as well as having a good stability, and therefore can be used in the food industry.
Trisodium citrate dihydrate has the greatest demand when being used as a food additive.
Trisodium citrate dihydrate is used as food additives.
Trisodium citrate dihydrate is mainly used as flavoring agents, buffers, emulsifiers, bulking agents, stabilizers and preservatives.
In addition, combination between Trisodium citrate dihydrate and citric acid can be used in a variety of jams, jelly, juice, drinks, cold drinks, dairy products and pastries gelling agents, flavoring agents and nutritional supplements.
In the food industry, Trisodium citrate dihydrate is used as a flavor enhancer, acidity regulator, and emulsifier.
Trisodium citrate dihydrate is also an essential ingredient in dishwasher tablets, industrial cleaners, detergents, etc.
Trisodium citrate dihydrate gets used in a many different places in food and beverage manufacture, though it's mainly used as a food additive for flavor and / or as a preservative.
Soft drinks, energy drinks, and club soda all use Trisodium citrate dihydrate for its tart flavour.
Trisodium citrate dihydrate is also used as a pH buffering agent in places like gelatins or mini milk containers.
Trisodium citrate dihydrate is also used as an anti-coagulant, Trisodium citrate dihydrate is ideal for keeping the fat globules from sticking together in the manufacture of many things such as ice cream.
Trisodium citrate dihydrate can be used as a food additive, as complex agent and buffering agent in electroplating industry; at the field of pharmaceutical industry.
Trisodium citrate dihydrate is used for the manufacturing of anti-clotting drugs; and used as the detergent additives in light industry.
Trisodium citrate dihydrate is used as the analysis agents used for chromatography analysis and can also used for preparing bacterial culture medium.
Moreover, Trisodium citrate dihydrate can also be applied into pharmaceutical industry.
Trisodium citrate dihydrate can be used for the flavoring processing of food, as stabilizers, buffers and deputy complex-forming agents in non-toxic electroplating industry; at pharmaceutical industry.
Trisodium citrate dihydrate is used as anti-clotting agent, phlegm drugs and diuretics drugs.
Trisodium citrate dihydrate can also be used in brewing, injection, newspaper and movies medicines.
Trisodium citrate dihydrate is chiefly used as a food additive, usually for flavor or as a preservative.
Trisodium citrate dihydrate is used as an anticoagulant for collection of blood.
Trisodium citrate dihydrate is used in photography; as sequestering agent to remove trace metals; as emulsifier, acidulant and sequestrant in foods.
Trisodium citrate dihydrate is used as an anticoagulant also used as a biological buffer
Trisodium citrate dihydrate, is widely applied in food, beverages and fillers as a buffering, sequestering or an emulsifying agent.
Trisodium citrate dihydrate used as an anticoagulant in blood transfusions, osmotic laxative, functional fluids, solvents cleaning, furnishing care products, laundry dishwashing products and cleaning automobile radiators.
Pharmaceutical Applications:
Trisodium citrate dihydrate, as either the dihydrate or anhydrous material, is widely used in pharmaceutical formulations.
Trisodium citrate dihydrate is used in food products, primarily to adjust the pH of solutions.
Trisodium citrate dihydrate is also used as a sequestering agent.
The anhydrous material is used in effervescent tablet formulations.
Trisodium citrate dihydrate is additionally used as a blood anticoagulant either alone or in combination with other citrates such as disodium hydrogen citrate.
Therapeutically, Trisodium citrate dihydrate is used to relieve the painful irritation caused by cystitis, and also to treat dehydration and acidosis due to diarrhea.
Industrial Applications:
Feed & Pet Food
Pharma
Other Applications:
Anticoagulant activity
Use as buffer or food preservatives
Citrate solution is designed to break protein cross-links
As a calcium chelator
Food
Beverages
Healthcare
Personal Care
Cleaners & Detergents
Buffering agent.
Manufacture of household cleaners, degreasers and detergents.
Effect And Application:
During the process of clinically taking fresh blood, adding some amount of sterile sodium citrate can play a role in prevent blood clotting; this is exactly taking advantage of the features that calcium citrate can form soluble complexes with calcium ion.
In the field of medicine, Trisodium citrate dihydrate is used for the in vitro anti-clotting drugs and anticoagulants drugs, phlegm drugs, and diuretics drugs during blood transfusions.
Trisodium citrate dihydrate can also used for cyanide-free electroplating industry.
Trisodium citrate dihydrate is also used as developer for photographic industry.
Trisodium citrate dihydrate can be used as flavoring agents, buffering materials, emulsifiers, and stabilizer in the food industry.
Moreover, Trisodium citrate dihydrate is also widely used in chemical, metallurgical industry, the absorption of sulfur dioxide exhaust with the absorption rate of 99% and regenerate liquid sulfur dioxide citrate for recycle application.
Trisodium citrate dihydrate has a good water solubility and a excellent cheating capability with Ca2 +, Mg2 + and other metal ions.
Trisodium citrate dihydrate is biodegradable and has a strong dispersing ability and anti-redeposition ability.
Daily-applied chemical detergents use Trisodium citrate dihydrate as alternative to trimer sodium phosphate for production of non-phosphorus detergent and phosphate-free liquid detergent.
Adding a certain amount Trisodium citrate dihydrate to the detergent can significantly increase the cleaning ability of detergent cleaning.
The large scale of application of sodium tripolyphosphate as a builder in detergents is an important discovery in synthetic detergent industry.
Trisodium citrate dihydrate is non-toxic without environmental pollution.
Trisodium citrate dihydrate can also be acted as a buffer for the production of cosmetics.
Functions And Applications:
Trisodium citrate dihydrate is used as acidity regulator, flavor agent and stabilizer in food and beverage industry.
Trisodium citrate dihydrate is used as an anticoagulant, phlegm dispersant and diuretic in the pharmaceutical industry.
In detergent industry, Trisodium citrate dihydrate can be substituted as non-toxic detergent additive.
Trisodium citrate dihydrate is also used in brewing, injection, photographic medicine and electroplating.
Main Functions:
pH regulator
Chelating agent
Buffering agent
Flavour enhancer
Stabiliser
Emulsifying agent
Characteristics of Trisodium citrate dihydrate:
Trisodium citrate dihydrate occurs as white, granular crystals or as white, crystalline powder.
Trisodium citrate dihydrate is an odourless substance with a pleasant, salty taste.
Trisodium citrate dihydrate is slightly deliquescent in moist air, freely soluble in water and practically insoluble in ethanol (96%).
Trisodium citrate dihydrate is a non-toxic, neutral salt with low reactivity.
Trisodium citrate dihydrate is chemically stable if stored at ambient temperatures.
Although Trisodium citrate dihydrate is not very hygroscopic, caking may occur upon prolonged storage at humidities higher than 70 %.
Trisodium citrate dihydrate is fully biodegradable and can be disposed of with regular waste or sewage.
Chemical Properties of Trisodium citrate dihydrate:
Trisodium citrate dihydrate is colorless crystals or white crystalline powder, and is odorless, cool and salty.
Trisodium citrate dihydrate has no melting point with a relative density of 1.857.
Trisodium citrate dihydrate is stable in air at room temperature with loss of crystal water when being heated to 150 °C loss of crystal water; further heating will cause its decomposition.
Trisodium citrate dihydrate is insoluble in ethanol but highly soluble in water. 5% aqueous solution has a pH value of 7.6 to 8.6.
Trisodium citrate dihydrate consists of odorless, colorless, monoclinic crystals, or a white crystalline powder with a cooling, saline taste.
Trisodium citrate dihydrate is slightly deliquescent in moist air, and in warm dry air Trisodium citrate dihydrate is efflorescent.
Key Benefits of Trisodium citrate dihydrate:
Non-toxic
Low Reactivity
Chemically stable
Fully biodegradable
Can be disposed of with regular waste or sewage
Excellent Performance of Trisodium citrate dihydrate:
Trisodium citrate dihydrate is currently the most important citrate.
Trisodium citrate dihydrate is produced by two steps: first starch food is fermented to generate citric acid.
Secondly, citric acid is neutralized by alkali to generate the final products.
Production Methods of Trisodium citrate dihydrate:
Trisodium citrate dihydrate is produced by the neutralization of citric acid by sodium hydroxide or sodium bicarbonate.
Dissolve sodium bicarbonate in water upon stirring and heating; add citric acid, continue to heat up to 85-90 °C; adjust the pH to 6.8; adjust active carbon for bleaching.
Filter when the mixture is still hot; condense the filtrate under reduced pressure; cool and the crystal comes out; filter, wash, dry to obtain the final products of
Trisodium citrate dihydrate.
C6H8O7 + 3NaHCO3 → C6H5Na3O7 • 2H2O + 3CO2 ↑ + H2O
Trisodium citrate dihydrate is prepared by adding sodium carbonate to a solution of citric acid until effervescence ceases.
The resulting solution is filtered and evaporated to dryness.
Safe And Nontoxic Properties of Trisodium citrate dihydrate:
Since the basic raw material for the preparation of Trisodium citrate dihydrate mainly comes from the food, Trisodium citrate dihydrate is absolutely safe and reliable without causing harm to human health.
The United Nations Food and Agriculture and the World Health Organization has no restriction in its daily intake, which means that this product can be considered as non-toxic food.
Trisodium citrate dihydrate is biodegradable.
After subjecting to the dilution of a large amount of water, Trisodium citrate dihydrate is partially converted into citrate, which coexists with sodium citrate in the same system.
Citrate is easy to subject to biological degradation at water by the action of oxygen, heat, light, bacteria and microbes.
Trisodium citrate dihydrate's decomposition pathways are generally going through aconitic acid, itaconic acid, citraconic acid anhydride to be further converted to carbon dioxide and water.
The ability to form complexes with metal ions.
Trisodium citrate dihydrate has a good capability of forming complex with some metal ions such as Ca2+, Mg2+; for other ions such as Fe2+, Trisodium citrate dihydrate also has a good complex-forming ability.
Excellent solubility, and the solubility increases with increasing temperature of water.
Trisodium citrate dihydrate has a good capability for pH adjustment and a good buffering property.
Trisodium citrate dihydrate is a weak acid-strong alkali salt; When combined with citrate, they can form a pH buffer with strong compatibility; therefore, this is very useful for some cases in which Trisodium citrate dihydrate is not suitable to have large change of pH value.
In addition, Trisodium citrate dihydrate also has excellent retardation performance and stability.
Biochem/Physiol Actions of Trisodium citrate dihydrate:
Trisodium citrate dihydrate can act as a buffering agent, resisting changes in pH.
Trisodium citrate dihydrate is used in blood collection tubes, the citrate chelates calcium ions in blood and thereby disrupts blood clotting.
Citrate is a intermediate in the TCA cycle and fatty acid synthesis.
Citrate is an allosteric modulator of acetyl-CoA carboxylase, the enzyme that regulates the conversion of acetyl-CoA to malonyl-CoA.
Handling And Storage of Trisodium citrate dihydrate:
Conditions for safe storage, including any incompatibilities:
Storage conditions:
Tightly closed.
Dry.
Stability And Reactivity of Trisodium citrate dihydrate:
Chemical stability:
Trisodium citrate dihydrate is chemically stable under standard ambient conditions (room temperature).
Conditions to avoid:
no information available
Incompatible materials:
No data available
First Aid Measures of Trisodium citrate dihydrate:
If inhaled
After inhalation:
Fresh air.
In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
Indication of any immediate medical attention and special treatment needed:
No data available
Fire Fighting Measures of Trisodium citrate dihydrate:
Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
Accidental Release Measures of Trisodium citrate dihydrate:
Environmental precautions:
Do not let product enter drains.
Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.
Exposure Controls/Personal Protection of Trisodium citrate dihydrate:
Personal protective equipment:
Eye/face protection:
Use equipment for eye protection.
Safety glasses.
Control of environmental exposure:
Do not let product enter drains.
Identifiers of Trisodium citrate dihydrate:
Chemical formula: Na₃C₆H₅O₇·2H₂O
CAS (Chemical Abstracts Service) number: 6132-04-3
PubChem CID (Compound Identifier): 71474
ChemSpider ID: 64404
EINECS (European Inventory of Existing Commercial Chemical Substances) number: 200-675-3
UNII (Unique Ingredient Identifier) code: 8Z96QXD6UM
Properties of Trisodium citrate dihydrate:
Molecular Weight: 294.10
Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 9
Rotatable Bond Count: 2
Exact Mass: 293.99396471
Monoisotopic Mass: 293.99396471
Topological Polar Surface Area: 143 Ų
Heavy Atom Count: 18
Formal Charge: 0
Complexity: 211
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 6
Compound Is Canonicalized: Yes
CAS number: 6132-04-3
EC number: 200-675-3
Hill Formula: C₆H₅Na₃O₇ * 2 H₂O
Molar Mass: 294.10 g/mol
HS Code: 2918 15 00
Melting Point: 300 °C (anhydrous substance)
pH value: 7.5 - 9.0 (50 g/l, H₂O, 25 °C)
Bulk density: 600 kg/m3
Solubility: 720 g/l
Appearance Form: powder
Color: white
Odor: No data available
Odor Threshold: No data available
pH: 7,5 - 9 at 29,4 g/l at 25 °C
Melting point/freezing point:
Melting point/range: > 300 °C
Initial boiling point and boiling range: No data available
Flash point: Not applicable
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Relative density: No data available
Water solubility: 29,4 g/l at 20 °C - completely soluble
Partition coefficient: n-octanol/water: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Water Solubility: 73.7 mg/mL
logP: -0.55
logP: -1.3
logS: -0.54
pKa (Strongest Acidic): 3.05
pKa (Strongest Basic): -4.2
Physiological Charge: -3
Hydrogen Acceptor Count: 7
Hydrogen Donor Count: 1
Polar Surface Area: 140.62 Å2
Rotatable Bond Count: 5
Refractivity: 68.14 m3·mol-1
Polarizability: 14.27 Å3
Number of Rings: 0
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: No
MDDR-like Rule: No
Melting Point: 150°C (in -2H2O)
Density: 1.76
Odor: Odorless
Quantity: 10,000 g
Beilstein: 6104939
Merck Index: 14,8602
Solubility Information: Soluble in water.
Insoluble in alcohol.
Formula Weight: 294.10 (258.07 Anhydrous)
Percent Purity: 99%
Chemical Name or Material: Trisodium citrate dihydrate
CAS No: 6132–04–3
EINECS No: 200–675–3
Empirical formula: C6H5Na3O7 . 2H2O
Molecular mass: 294.10 g/mol
Density: 1.7g/cm3
Appearance: colourless crystals or white, granular powder
pH: 8 – 8.7 at 50g/L at 25C
Melting point: >300 C
Solubility in water: 760 g/L (25C)
Easily soluble in hot water.
Soluble in cold water.
Insoluble in alcohol.
Soluble in 1.3 parts water.
Soluble in 0.6 parts boiling water.
Melting point: >300 °C(lit.)
Density: 1.76
FEMA: 3026 | SODIUM CITRATE
Flash point: 173.9 °C
storage temp.: Store at +5°C to +30°C.
solubility: H2O: 100 mg/mL
form: powder
color: white
PH: 7.0-9.0 (25℃, 50mg/mL in H2O)
Odor: Odorless
PH Range: 7.5 - 9 at 29.4 g/l at 25 °C
Water Solubility: 720 g/L (25 ºC)
λmax: λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01
Merck: 14,8602
BRN: 6104939
Stability: Stable.
Incompatible with bases, reducing agents, oxidizing agents.
Appearance: White crystals or crystalline powder
Odor: Characteristic
Clarity and color of Solution: Conforms
Loss on drying: 11.0 - 13.0%
Usage: acidity regulator etc.
Pb: < 10ppm
Assay: 99.0 - 101.0%
Chemical formula: C6H5O7Na3.2H2O
Sulfate (SO4): 150 ppm max
Chloride (Cl): 50 ppm max
Alkalinity: Conforms
Oxalate: 300 ppm max
Storage: in the shade cool
Boiling Point: 309.6 °C at 760 mmHg
Melting Point: 300ºC
Flash Point:155.2ºC
Density: 1.76 g/cm3
Solubility: Solubility in water, g/100ml: 77
Appearance: White powder or crystals
Storage: Store at RT.
Hazard Codes: Xi
Log P: -5.38120
PSA: 159.8
Refractive Index: 1.58
Risk Statements: R37/38
RTECS: GE7810000
Safety Statements: S24/25
Stability: Stable.
Specifications of Trisodium citrate dihydrate:
Purity: ≥99%
pH (1% solution in water): 7.5 - 9.0
Heavy Metals: Within specified limits
Loss on Drying: 10-13%
Residue on Ignition: Specified percentage
Microbial Limits: Compliant with safety standards
Solubility: Highly soluble in water
Packaging: Suitable for product stability and integrity.