Sodium ascorbate = Vitamin C sodium = Sodium salt of Ascorbic acid
CAS Number: 134-03-2
EC Number 205-126-1
E number: E301 (antioxidants, ...)
Chemical formula: C6H7NaO6
Molecular Weight: 198.11
Sodium ascorbate is one of a number of mineral salts of ascorbic acid (vitamin C).
The molecular formula of Sodium ascorbate compound is C6H7NaO6.
As the sodium salt of ascorbic acid, Sodium ascorbate is known as a mineral ascorbate.
Sodium ascorbate has not been demonstrated to be more bioavailable than any other form of vitamin C supplement.
Sodium ascorbate normally provides 131 mg of sodium per 1,000 mg of ascorbic acid (1,000 mg of sodium ascorbate contains 889 mg of ascorbic acid and 111 mg of sodium).
Sodium ascorbate (C6H7NaO6) is the sodium salt form of vitamin C that is more easily absorbed than ascorbic acid.
Sodium ascorbate can be given as an injection.
Sodium ascorbate is also found in osmotic laxatives indicated for cleansing of the colon as a preparation for colonoscopy.
Sodium ascorbate may also be found as an ingredient in other pharmaceutical products.
Sodium ascorbate can also be used as a food additive and is listed on the FDA list of generally recognized as safe (GRAS) substances.
As a food additive, Sodium ascorbate has the E number E301 and is used as an antioxidant and an acidity regulator.
Sodium ascorbate is approved for use as a food additive in the EU, USA, Australia, and New Zealand.
In in vitro studies, sodium ascorbate has been found to produce cytotoxic effects in various malignant cell lines, which include melanoma cells that are particularly susceptible.
Sodium ascorbate is a form of vitamin C that has sodium components that help lower its acidity levels.
The sodium content helps vitamin C to be easily absorbed and stay longer in the body.
Sodium ascorbate serves as an antioxidant that helps keep your cells from damage and keep them healthy.
Sodium Ascorbate is a non-bitter, non-acidic, fully reacted, buffered, crystalline powder combining 100% pharmaceutical grade vitamin C and sodium in a highly soluble form.
Vitamin C and sodium are essential nutrients that help support the body.
Sodium ascorbate provides antioxidant protection to the immune system, as well as maintains the health of blood vessels, tissue, cartilage, bones, eyes, and other organ systems.
Sodium ascorbate is also required for the biosynthesis of collagen, L-carnitine, and neurotransmitters.
Sodium is an electrolyte that helps maintain the balance of water in and around cells, maintain stable blood pressure, and is important for muscle and nerve function.
The combined positive effects of vitamin C and sodium make them vital to the body’s overall health.
Each serving supplies 1100 mg of vitamin C and 120 mg of sodium.
Sodium Ascorbate is manufactured by dissolving L-ascorbic acid with sodium hydrogen carbonate mined from the earth.
The sodium in Sodium ascorbate differs from common table salt, as it is not combined with chloride.
Sodium Ascorbate is ideal for individuals looking for an alkaline (buffered) form of vitamin C.
Sodium Ascorbate is the sodium salt of ascorbic acid.
Sodium ascorbate can be used both as a nutrient (vitamin C) and as an additive (antioxidant).
We have two types of sodium ascorbate available: ‘P1914’ is the regular sodium ascorbate, ‘P19141’ is the DC (Directly Compressible) grade.
The DC grade material is more granular and is more suitable for tablet/capsule applications.
The DC grade material contains 1% Corn Starch to help with the compressibility and therefore is only 99% sodium ascorbate.
Sodium ascorbate might be beneficial over ascorbic acid because it is buffered by the sodium, making it less acidic.
This might be beneficial for those who suffer from gastrointestinal side effects when they take other forms of vitamin C.
Please note that doses (more than 1000mg of vitamin C) may cause mild stomach upset in sensitive individuals.
Applications of Sodium ascorbate:
Sodium Ascorbate is a mineral salt of Ascorbic Acid, a physiological antioxidant.
Coenzyme for a number of hydroxylation reactions; required for collagen synthesis.
Widely distributed in plants and animals. Inadequate intake results in deficiency syndromes such as scurvy.
Sodium ascorbate is used as antimicrobial and antioxidant in foodstuffs.
Sodium ascorbate is a vitamin C supplement that’s available as a powder or capsule supplement.
Sodium ascorbate delivers extra vitamin C when your diet is lacking or if you have a condition that calls for an extra dose of this crucial nutrient.
Sodium ascorbate is a form of ascorbic acid (Vitamin C) which is more bioavailable and “alkaline”, unlike the ascorbic acid form of the C vitamin, which leads to stomach upset in some people.
However, the drawback is the sodium content of this preparation, which is 131 mg of sodium salt per 1,000 mg of ascorbic acid, enough to aggravate existing hypertension or heart failure among some of these patients.
Also, in general, minimizing salt (sodium) intake is recommended for everyone, except for patients with diarrhea or other conditions where sodium deficiency is present.
Sodium ascorbate is also used as a food additive.
What Is Sodium Ascorbate Powder (Vitamin C)?
Sodium ascorbate powder is a mineral salt of ascorbic acid that is made by combining sodium bicarbonate with ascorbic acid (vitamin C).
Vitamin C is an essential vitamin that is well known for its effects on the immune system.
Sodium ascorbate powder has a natural sour taste, which is why Sodium ascorbate's commonly used in candy.
When Sodium ascorbate is ingested, Sodium ascorbate helps in the fortification of collagen while acting as an antioxidant.
Sodium ascorbate also assists in the repair of damaged tissue, and in helping to maintain healthy levels of collagen.
Sodium ascorbate also has a host of other general uses.
Sodium Ascorbate Powder (Vitamin C) Benefits
Sodium ascorbate powder (vitamin C) is an essential vitamin and is well known for working with other enzymes and solutions.
Sodium ascorbate assists the body in building new tissue and helps fortify the immune system.
Sodium ascorbate can help strengthen collagen and assists in synthesizing carnitine and supporting healthy metabolism.
Sodium ascorbate also helps fortify the teeth and bones.
Sodium ascorbate is known for its antioxidant properties, and it supports cardiovascular health.
When used topically, Sodium ascorbate may also help promote healthy skin.
-Fortifies the immune system
-Supports healthy tissue and cartilage
-Helps support healthy metabolism
-Supports the joints
-Contributes to healthy bones & teeth
-Promotes healthy skin
-Supports cardiovascular health
Sodium Ascorbate is a form of the mineral salt of ascorbic acid.
Sodium Ascorbate provides 131 mg of sodium per 1,000 mg of ascorbic acid.
These are mainly used as a food additive and are also used as an antioxidant, and an acidity regulator.
Sodium Ascorbate acts as a vitamin in a case of there being a deficiency of vitamin C in the body and it is known for its antioxidant properties.
However, the primary use of Sodium Ascorbate is to prevent and treat the vitamin C deficiency in the body.
Due to the vitamin C deficiency, a disease called Scurvy can occur due to which one may suffer from body rashes, muscle weakness, joint pain, and tooth decay.
Sodium Ascorbate, commonly known as vitamin C, is used in various important ends use industries such as pharmaceuticals, personal care, food and beverages, and others.
However, pharmaceutical industry holds for the largest consumer of Sodium Ascorbate.
As vitamin C helps in the reprocessing on vitamin E, the earlier is used for formulating vitamin C supplements in the pharmaceutical industry.
In the food and beverages industry, Sodium Ascorbate is used as an additive to enhance food quality and improve the stability of food.
Also, the added benefit of using these in food products is that Sodium ascorbate helps to preserve the aroma, color and nutrient content of the food.
Sodium ascorbate is found in citrus fruits and vegetables.
Sodium ascorbate is synthesized from ascorbic acid and sodium bicarbonate.
In 1935, the inhibiting effect of ascorbates and other salts on proteases was reflected in improved flour quality.
Function of Sodium ascorbate:
This ingredient serves several purposes in baked goods:
Antioxidant and reducing agent: by reacting with free radicals it produces inactive compounds that disrupt free radical chain reactions.
Dough conditioner: stabilizes the gluten network by reducing extensibility and increasing elasticity.
Acidity regulator: contributes to acidity regulation unlike ascorbic acid that tends to increase dough acidity.
Bread improver: helps improve volume, shape and texture of baked goods.
Taste: provides a desirable tart flavor in candies and fruit juices.
The commercial claims about sodium ascorbate are exemplified by the following: ”Sodium ascorbate can reverse the development of atherosclerotic disease, helps in heart attack prevention.
In addition sodium ascorbate plays a significant role in the elimination of chronic and acute infections.
Moreover, Sodium ascorbate is considered to be an anti-cancer agent.
Sodium ascorbate produces cytotoxic effect in an array of malignant cell lines, which include melanoma cells that are particularly susceptible.”
The pertinent ingredient in this formulation is the vitamin C in it and NOT the sodium or its ascorbate form, and yet the misleading implication is that the sodium ascorbate form is a “wonder drug.”
This assertion (bordering on public deception) that sodium ascrobate has “that exclusive action” compared to regular ascorbic acid (vitamin C), is a myth, and could not be further from the truth.
The main active ingredient in both is the ascorbic acid.
The benefits Sodium ascorbate each confer to the body are the same.
The “special” formulation, which costs 4 or 8 times more, is obviously for marketing purposes, a gimmick that is part of the trillion dollar food supplement scam around the world, rampant today.
If one needs vitamin C, ascorbic acid or calcium ascorbate will work just as well, minus the sodium and its bad effect, and at a fraction of the price also.
Who needs vitamin C?
All of us need Vitamin C for health and deficiency of this vitamin causes scurvy, which afflicted sailors on long voyages centuries ago, because their diet was deficient in this vitamin for lack of vegetables and fruits on their ships.
But today, as a rule, people who eat normally do not lack vitamin C in their system.
Vitamin C supplement is actually not necessary unless gastrointestinal problem, like mal-absorption, is present.
Also, the multivitamin and minerals most people take once daily already contain 60 mg – 90 mg of ascorbic acid, which meets our daily need.
Megadose of any vitamin is unsafe.
What does vitamin C do?
Sodium ascorbate is essential to maintain health of our skin, bones, teeth, cartilage, and blood vessels.
Vitamin C is needed by the body to form collagen and also enhances the absorption of iron from plant-based foods we eat.
Together with the other vitamins and minerals, ascorbic acid is important for those with macular (eye) degeneration.
Sodium ascorbate is also an antioxidant that helps protect our body cells from damages from daily wear and tear, and useful for the integrity of our immune system.
What are the side effects?
Most people can tolerate vitamin C, in either form.
Some may develop abdominal cramps, heartburns, nausea, vomiting, constipation or diarrhea, while others may be allergic to it, causing itching, swelling, dizziness, and some, difficulty in breathing.
But these are not very common.
In general, vitamin C (ascorbic acid or sodium ascorbate, or calcium ascorbate) are well-tolerated.
When taken in excess, vitamin C will lead to nausea, diarrhea, and stomach cramps.
Among those with a disease called Hemochromatosis, where the body stores too much iron, high doses of Vitamin C could result in worsening of the iron overload and damage body
Vitamin C is essential for human health mainly to prevent common cold, infections and gum disease and in maintaining proper immune function.
One concern with this ingredient is Sodium ascorbates sodium content which may have undesirable consequences such as water retention, hypertension, kidney and heart disease.
Commercial production of Sodium ascorbate:
Sodium ascorbate can be industrially produced by two methods: reacting ascorbic acid with sodium bicarbonate, and via gulonic acid.
Ascorbic acid and sodium bicarbonate method:
Reaction: ascorbic acid is dissolved in water followed by addition of alkaline sodium bicarbonate.
Solvent addition: to precipitate sodium ascorbate.
Filtration: resulting sodium ascorbate is filtered and washed with a small amount of solvent.
Drying: the obtained salt is air-dried.
Applications of Sodium ascorbate:
In addition to Sodium ascorbates dough conditioning power, Sodium ascorbate can help increase shelf life and dough quality of breads and rolls.
Sodium ascorbate is best used in no-time doughs.
Sodium ascorbate can be added dry to the flour or as a solution in the dough, at a 0.1%.
Substituting ascorbic acid by sodium ascorbate should take into consideration that one part of the salt is equivalent to 1.09 parts of ascorbic acid.
Therefore, for 1-20 g ascorbic acid/Kg flour is equivalent to 0.9 – 18.35 g/100 Kg sodium ascorbate.
Applications of Sodium ascorbate:
(+)-Sodium L-ascorbate has been used:
Sodium ascorbate is used as a component of cutting solution for storing brain slices of rats
Sodium ascorbate is used as a component of patch pipette internal solution for imaging Ca2+ transients evoked by action potential in rat brain slices
Sodium ascorbate is used as a supplement for arterial smooth muscle cell (SMC) cultures to encourage collagen production
Production of Sodium ascorbate:
Sodium ascorbate is produced by dissolving ascorbic acid in water and adding an equivalent amount of sodium bicarbonate in water.
After cessation of effervescence, the sodium ascorbate is precipitated by the addition of isopropanol.
Sodium Ascorbate is the sodium salt of ascorbic acid.
Sodium ascorbate appears in small white to yellow crystals and is soluble in water and slightly soluble in alcohol.
Sodium Ascorbate is approved as a food additive in the USA, EU, Australia, and New Zealand.
Sodium ascorbate is used as an antioxidant and an acidity regulator.
Occasionally, Sodium ascorbate is used for preservation of diagnostic medicinals.
What is Sodium Ascorbate?
Sodium ascorbate is one of the mineral sales of ascorbic acid (Vitamin C).
Sodium ascorbate is alkaline.
Ascorbic acid is acidic and may cause stomach issues related to acid reflux.
Since sodium ascorbate is alkaline, it is much less likely to cause such issues.
Sodium ascorbate taken as a supplement will supply your body with both vitamin C (ascorbic acid) and sodium.
What is Sodium Ascorbate used for?
Vitamin C, also known as L-ascorbic acid, is a water-soluble, unstable vitamin that is the main antioxidant compound for our skin.
Sodium ascorbate is a vital component of our skin structure and function.
Topical vitamin C has a wide range of clinical applications, from antiaging and anti-pigmentation to skin photoprotection as well as being a known enhancer of skin collagen and elastin production.
Humans, unlike most animals, are unable to synthesize vitamin C endogenously, so it is an essential dietary component.
Sodium ascorbate can be successfully applied topically to our skin to deliver significant benefits
How Sodium Ascorbate is classified
Recommendation for Sodium Ascorbate in pregnancy and breastfeeding
Limited data suggests no known risk
CAS Number: 134-03-2
ECHA InfoCard: 100.004.661
EC Number 205-126-1
E number: E301 (antioxidants, ...)
PubChem CID: 23667548
RTECS number: CI7671000
CompTox Dashboard (EPA): DTXSID0020105
Sodium ascorbate will also neutralize chlorine.
Sodium ascorbate is pH neutral and will not change the pH of the treated water.
Sodium ascorbate is preferable for neutralizing high concentrations of chlorine.
If a large amount of treated water is going to be discharged to a small stream, the pH of the treated water and the stream should be within 0.2 to 0.5 units of the receiving stream.
The reaction (Tikkanen and others 2001) of sodium ascorbate with chlorine is shown below:
C5H5O5CH2ONa + HOCL → C5H3O5CH2OH + NaCl + H2O
Sodium ascorbate + Hypochlorous acid → Dehydroascorbic acid + Sodium chloride + water
Approximately 2.8 parts of sodium ascorbate are required to neutralize 1 part chlorine.
When vitamin C is oxidized, a weak acid called dehydroascorbic acid forms.
Several studies have evaluated the use of ascorbic acid and sodium ascorbate to neutralize low levels of chlorine less than 2 milligrams per liter.
Only one study (Tacoma Water Utility Report) evaluated the use of ascorbic acid to neutralize high levels of chlorine up to 100 milligrams per liter.
The Tacoma, WA, Water Utility Engineer recommends against using ascorbic acid to neutralize high levels of chlorine in large volumes of water because it lowers the pH of the treated water.
The Tacoma Water Utility engineer recommends using sodium ascorbate instead.
Chemical formula: C6H7NaO6
Molar mass: minute white to yellow crystals
Density: 1.66 g/cm3
Melting point: 218 °C (424 °F; 491 K) (decomposes)
Solubility in water:
62 g/100 mL (25 °C)
78 g/100 mL (75 °C)
very slightly soluble in alcohol
insoluble in chloroform, ether
Physical Appearance: A solid
Storage: Store at -20°C
Cas No.: 134-03-2
Solubility: insoluble in EtOH; insoluble in DMSO; ≥9.1 mg/mL in H2O
Chemical Name: sodium (R)-2-((S)-1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate
Evaluation sample solution: ship with blue ice.
All other available sizes: ship with RT, or blue ice upon request.
L-ascorbic acid sodium salt
L(+)-ascorbic acid sodium salt
laevo-ascorbic acid sodium salt
laevo-ascorbic acid sodium salt (1:1)
L-ascorbic acid, monosodium salt
L-ascorbic acid, sodium salt (1:1)
vitamin C sodium
vitamin C sodium salt
Vitamin C with Sodium Ascorbate:
Sodium Ascorbate is a highly absorbable form of Vitamin C that is non-acidic and gentle on the stomach.
Vitamin C powder is buffered with 100% pure Sodium Ascorbate for maximum absorption.
General tips about Sodium ascorbate:
For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while.
Stock solution can be stored below -20°C for several months.
Active ingredient: Sodium ascorbate
Description: White, fine granular
Primary Use: Dechlorination of water
Synonyms: Vita-D-Chlor Neutral; sodium ascorbate, vitamin C
Certification: NSF/ANSI Standard 60 to 12 mg/L (Vita-D-Chlor, Neutral manufactured by Integra Chemical Co.)
Shelf life: Up to 3 years
Solution pH: Great for treatment of high chlorine levels because it remains pH neutral (pH 7) at all concentrations
Solubility in water: Highly soluble for concentrations of up to 50% (4 lbs per gallon)
Usage rate to neutralize 1 ppm Cl in water: ~1 gram/100 gallons or 1 lb per 45,000 gallons
Sodium Ascorbate is a form of Vitamin C.
Trade Ingredients are a global supplier of Buffered Sodium Ascorbate Powder.
We purchase this product in huge bulk enabling us to sell at very competitive prices.
Our Sodium Ascorbate Powder is widely used in pharmaceutical applications, nutritional produacts and food & beverage products throughout the world.
Our Sodium Ascorbate is soluble in water.
Our Sodium Ascorbate is manufactured in an FDA approved facility and to all of the relevant Pharmacopoeia requirements.
Sodium Ascorbate is found to be gentler on the stomach than Ascorbic Acid.
Melting point:220 °C (dec.)(lit.)
alpha 104 º (c=1, H2O 25 ºC)
Boiling point:235 °C
refractive index 105.5 ° (C=10, H2O)
storage temp. Store at RT.
solubility H2O: 50 mg/mL
color white to slightly yellow
PHpH (20g/l, 25℃) : 6.5～8.0
optical activity[α]20/D +105±2°, c = 5% in H2O
Water Solubility 620 g/L (20 ºC)
Stability:Stable. Incompatible with strong oxidizing agents.
Sodium ascorbate (vitamin C) is particularly useful for dechlorination of large tanks due to its quick dissolve rate.
Sodium ascorbates viability as a substitute for sulfite dechlorination is only an economic decision as its benefits are clear on an environmental basis due to the tendency of sulfites to deplete oxygen.
When compared with ascorbic acid (also vitamin C), the neutral pH of sodium ascorbate makes it the preferred option for treating large volumes of water that contain high levels of chlorine (>10 ppm).
L-Ascorbic acid sodium salt
Vitamin C sodium
Ascorbic acid sodium salt
Vitamin C, sodium salt
Ascorbate de sodium
Sodium ascorbate occurs as a white or slightly yellow-colored, practically odorless, crystalline powder with a pleasant saline taste.
white to off-white solid
Uses of Sodium ascorbate:
L-Ascorbic acid (Vitamin C) is a water soluble molecule used in a wide variety of applications, including cell culture, as a reducing agent that helps reduce oxidative stress.
As antimicrobial and antioxidant in foodstuffs.
Sodium Ascorbate is an antioxidant that is the sodium form of ascorbic acid.
Sodium ascorbate is soluble in water and provides a nonacidic taste. a 10% aqueous solution has a ph of 7.3–7.6.
in water, Sodium ascorbate readily reacts with atmospheric oxygen and other oxidizing agents, making it valuable as an antioxidant.
one part sodium ascorbate is equivalent to 1.09 parts of sodium erythorbate.
Definition of Sodium ascorbate:
ChEBI: An organic sodium salt resulting from the replacement of the proton from the 3-hydroxy group of ascorbic acid by a sodium ion.
Sodium ascorbate production Methods:
An equivalent amount of sodium bicarbonate is added to a solution of ascorbic acid in water.
Following the cessation of effervescence, the addition of propan-2-ol precipitates sodium ascorbate.
L-Ascorbic acid, monosodium salt
L(+)-Ascorbic acid sodium salt
Vitamin C Sodium Salt
Ascorbato sodico [DCIT]
Sodium ascorbate description:
Sodium ascorbate is sodium salt of ascorbic acid (commonly known as vitamin C), which is approved for use as a food additive in many countries.
Sodium ascorbate is consisted of a combination of sodium and vitamin C, which commonly serve as an antioxidant and an acidity regulator in pharmaceutical manufacturing and in the food industry.
In this mixture, sodium acts as a buffer, creating a less acidic supplement than those made entirely from vitamin C.
Sodium ascorbate can be easier to tolerate if the digestive system is sensitive to acid.
As a vitamin C supplement, Sodium ascorbate provides both sodium and vitamin C for human body, which is effective to prevent or treat vitamin C deficiency.
Besides, studies have shown that taking sodium ascorbate is helpful with cancer prevention and treatment.
Natrii ascorbas [INN-Latin]
Ascorbic acid sodium derivative
L-Ascorbic acid sodium
Ascorbate de sodium [INN-French]
Sodium ascorbate [USP:INN]
L-Ascorbic acid, sodium salt (1:1)
Sodium derivative of 3-oxo-L-gulofuranolactone
ascorbic acid sodium
Sodium Ascorbate contains 88.9% Vitamin C and 11.1% Sodium by mass.
As this material is only 99% Sodium Ascorbate, the overall material contains ~88% Vitamin C and ~11% Sodium.
Therefore, to obtain the following label claims, you would require these quantities of DC grade sodium ascorbate preparation
12mg Vitamin C (15%) RI:* : 13.6mg of Sodium Ascorbate
24mg Vitamin C (30%) RI:* : 27.3mg of Sodium Ascorbate
80mg Vitamin C (100%) RI* : 90.9mg of Sodium Ascorbate
sodium L-ascorbate salt
L(+)Ascorbic acid sodium salt
L-Ascorbic Acid Sodium Salt,(S)
L-Ascorbic Acid - Monosodium Salt
Both ascorbic acid and sodium ascorbate are good sources of antioxidants and help boost your immune health.
However, since ascorbic acid is an organic acid, it can increase in the PH levels in your stomach and may trigger hyperacidity for those who are suffering from it.