Tetradecanoic acid is a saturated fatty acid with a 12-carbon atom chain, found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.
Tetradecanoic acid and its glycerides possess strong antibacterial properties, especially against Gram-positive pathogenic bacteria, by interfering with the cell membrane and disturbing vital cell processes.
Tetradecanoic acid is widely used in the manufacturing of soaps, detergents, and personal care products, and also shows potential in medical applications for treating viral infections and as a penetration enhancer for drug delivery systems.
CAS Number: 143-07-7
EC Number: 205-582-1
Molecular Formula: C12H24O2
Molar Mass: 200.322 g·mol−1
Synonyms: Emery651, Dodecanoic Acid(C12:0), Lauric acid 98%, yeuguisuan, Laurosteaic acid, Lauric acid 98-101 % (acidimetric), lauric acid, pure, LAURIC ACID, 99.5+%, LAURIC ACID, STANDARD FOR GC, LAURIC ACID 98+% FCC, LAURIC ACID 98+% NATURAL FCC, LauricAcid99%Min., LauricAcidPureC12H24O2, Lauric Acid-methyl-D3, lauricacid,dodecanoicacid, n-Dodecanoic, LAURICACID,REAGENT, LAURIC ACID(SG), LAURIC ACID FCC, LAURIC ACID, NATURAL & KOSHER, LAURIC ACID, NATURAL & KOSHER (POWDER), Dodecanoic acid, typically 99%, N-DODECANOIC ACID, RARECHEM AL BO 0156, acidelaurique, Aliphat no. 4, AliphatNo.4, C-1297, Dodecanoic (Lauric) acid, dodecanoic acid (lauric acid), Dodecansαure, Dodecylic acid, dodecylicacid, Duodecyclic acid, Duodecylic acid, duodecylicacid, Emery 650, 1-Dodecanoic acid, LAURINSAEURE, Lauric acid,99.8+%, Lauric acid,95%, Lauric acid,99%, Dodecanoic acid, typically 99.5%, NSC 5026, Palmac 99-12, Trichloroacetic acid lauryl ester, Hendecane-1-carboxylic acid, Lauric acid≥ 98% (GC), AKOS 222-45, C12, C12:0 ACID, CARBOXYLIC ACID C12, LAUROSTEARIC ACID, LAURIC ACID, FEMA 2614, DODECOIC ACID, DODECANOIC ACID, 1-Undecanecarboxylic acid
Tetradecanoic acid is a saturated fatty acid with a 12-carbon atom chain, thus having many properties of medium-chain fatty acids, is a bright white, powdery solid with a faint odor of bay oil or soap.
The salts and esters of Tetradecanoic acid are known as laureates.
Tetradecanoic acid is found in many vegetable fats, particularly in coconut and palm kernel oils.
People use Tetradecanoic acid as medicine.
Tetradecanoic acid belongs to the class of organic compounds known as medium-chain fatty acids.
These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms.
Tetradecanoic acid is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral.
Tetradecanoic acid is a potentially toxic compound.
Tetradecanoic acid is a saturated fatty acid with a 12-carbon atom chain.
The powdery, white crystalline acid has a slight odor of oil of bay and occurs naturally in various plant and animal fats and oils.
Tetradecanoic acid is a major component of coconut oil and palm kernel oil.
Tetradecanoic acid is used as an intermediate and surface active agent in industry and in the manufacture of personal care products in the consumer market.
Tetradecanoic acid is a saturated medium-chain fatty acid with a 12-carbon backbone.
Tetradecanoic acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.
Tetradecanoic acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression.
Tetradecanoic acid is a solid at room temperature but melts easily in boiling water, so liquid Tetradecanoic acid can be treated with various solutes and used to determine their molecular masses.
Glycerides of Tetradecanoic acid are produced by an esterification reaction between Dodecanoic Acid and glycerol creating a covalent bond between these two molecules.
They show to possess strong antibacterial properties, especially against Gram-positive pathogenic bacteria.
Tetradecanoic acid glycerides interfere with the cell membrane and disturbs vital cell processes of the bacteria.
Tetradecanoic acid is a saturated fatty acid with a 12-carbon atom chain, thus having many properties of medium-chain fatty acids, is a bright white, powdery solid with a faint odor of bay oil or soap.
The salts and esters of Tetradecanoic acid are known as laurates.
Tetradecanoic acid is a medium-length long-chain fatty acid, or lipid, that makes up about half of the fatty acids within coconut oil.
Tetradecanoic acid’s a powerful substance that is sometimes extracted from the coconut for use in developing monolaurin.
Monolaurin is an antimicrobial agent that is able to fight bacteria, viruses, yeasts, and other pathogens.
Because you can’t ingest Tetradecanoic acid alone (it’s irritating and not found alone in nature), you’re most likely to get Tetradecanoic acid in the form of coconut oil or from fresh coconuts.
Though coconut oil is being studied at a breakneck pace, much of the research doesn’t pinpoint what in the oil is responsible for Tetradecanoic acid reported benefits.
Because coconut oil contains much more than just Tetradecanoic acid, Tetradecanoic acid would be a stretch to credit Tetradecanoic acid with all of the coconut oil benefits.
Still, a 2015 analysis suggests that many of the benefits tied to coconut oil are directly linked to Dodecanoic Acid.
Among the benefits, they suggest Tetradecanoic acid could aid weight loss and even protect against Alzheimer’s disease.
Tetradecanoic acids effects on blood cholesterol levels still need to be clarified.
This research suggests that the benefits of Tetradecanoic acid are due to how the body uses Tetradecanoic acid.
The majority of Tetradecanoic acid is sent directly to the liver, where Tetradecanoic acid converted to energy rather than stored as fat.
When compared with other saturated fats, Tetradecanoic acid contributes the least to fat storage.
Tetradecanoic acid, the saturated fatty acid with a 12-carbon atom chain, thus falling into the medium chain fatty acids, is a white, powdery solid with a faint odor of bay oil or soap.
Tetradecanoic acid is a naturally occurring compound found in a variety of animal and vegetable fats and oils, particularly coconut oil and palm kernel oil.
Tetradecanoic acid is carried to the whole body by lymphatic portal systems.
Tetradecanoic acid is a saturated fatty acid with a 12-carbon atom chain, thus having many properties of medium-chain fatty acids, is a bright white, powdery solid with a faint odor of bay oil or soap.
The salts and esters of Tetradecanoic acid are known as laureates a fatty acid, CH3(CH2)10COOH, occurring in coconut, palm and laurel oil; mostly used in making cosmetics and soaps dodecanoic acid, fatty crystalline acid that is mostly found in coconut and laurel oil (used to make soaps, cosmetic products, etc.) a crystalline fatty acid occurring as glycerides in natural fats and oils (especially coconut oil and palm-kernel oil)
Tetradecanoic acid is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
Tetradecanoic acid is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
To reap the topical benefits of Tetradecanoic acid and coconut oil, apply Tetradecanoic acid directly to your skin.
While this isn’t recommended for people with acne, the risks are minimal when Tetradecanoic acid comes to addressing issues such as skin hydration and psoriasis.
Tetradecanoic acid is the most abundant fatty acid present in coconut oil.
Tetradecanoic acid is also one of the main flavor constituents of Chinese rice wine and sweet cream butter.
Tetradecanoic acid is commonly used in lubricants and also in edible-coating formulations.
Tetradecanoic acid is a saturated fat.
Tetradecanoic acid is found in many vegetable fats, particularly in coconut and palm kernel oils.
People use Tetradecanoic acid as medicine.
Tetradecanoic acid is used for treating viral infections including influenza (the flu); swine flu; avian flu; the common cold; fever blisters, cold sores, and genital herpes caused by herpes simplex virus (HSV); genital warts caused by human papillomavirus (HPV); and HIV/AIDS.
Tetradecanoic acid is also used for preventing the transmission of HIV from mothers to children.
Other uses for Tetradecanoic acid include treatment of bronchitis, gonorrhea, yeast infections, chlamydia, intestinal infections caused by a parasite called Giardia lamblia, and ringworm.
In foods, Tetradecanoic acid is used as a vegetable shortening.
In manufacturing, Tetradecanoic acid is used to make soap and shampoo.
Tetradecanoic acid and myristic acid are saturated fatty acids.
Their formal names are dodecanoic acid and Vulvic acid, respectively.
Both are white solids that are very slightly soluble in water.
Tetradecanoic acid esters (principally triglycerides) are found only in vegetable fats, primarily from coconut milk and oil, laurel oil, and palm kernel oil.
In contrast, myristic acid triglycerides occur in plants and animals, notably in nutmeg butter, coconut oil, and mammalian milk.
Fatty acids have a bad name because they are strongly associated with high serum cholesterol levels in humans.
Lauric and myristic acids are among the worst offenders; therefore, many governmental and health organizations advise that coconut oil and milk, among other high–saturated fat substances, should be excluded from the diet.
Glycerides of Tetradecanoic acid are gaining more interest in the fight against viral diseases.
Their molecular structure makes them able to attack fat-enveloped viruses by destroying their fat-envelope.
Several in vitro trials reveal that the antiviral effects of Tetradecanoic acid glycerides are outperforming glycerides of other MCFAs.
Globally, glycerides of Tetradecanoic acid are applied to suppress the negative impact of Infectious Bronchitis (IB), Newcastle Disease (ND), Avian Influenza (AI), Marek’s disease (MD) and others.
As a result of the multiple actions of Tetradecanoic acid glycerides, FRA C12 is a successful tool in antibiotic free diets.
One will notice a reduction in curative antibiotic usage as well as improved animal health and performance with the use of glycerides of Tetradecanoic acid.
Tetradecanoic acid is a versatile oleochemical with applications in everything from plastics to personal care.
Found in numerous plants including the palm tree and cohune palm, as well as in coconut oil, palm seeds, betel nuts and macadamia nuts, Tetradecanoic acid is classified as a saturated fat featuring a 12-carbon atom chain.
There are some researchers who believe that Tetradecanoic acid may be safer than trans-fats when used in food preparation.
Tetradecanoic acid is a white, powdery solid that exhibits a slight odor reminiscent of bay oil or soap.
As with most fatty acids, Tetradecanoic acid is non-toxic, making Tetradecanoic acid safe for use in a wide range of applications.
Additionally, Tetradecanoic acid is relatively inexpensive, making Tetradecanoic acid a popular ingredient in manufacturing processes where cost is a key consideration.
Tetradecanoic acid is a saturated fatty acid.
Tetradecanoic acid is a white coat that is slightly soluble in water.
Tetradecanoic acid esters (mainly triglycerides) are only found in vegetable oils, particularly coconut milk and oil, bay oil, and palm kernel oil.
In contrast, myristic acid triglycerides occur in plants and animals, particularly nutmeg oil, coconut oil, and mammalian milk.
Fatty acids have a bad name because they are strongly associated with high serum cholesterol levels in humans.
Lauric and myristic acids are among the worst offenders;
Tetradecanoic acid is a saturated fatty acid with a chain of 12 carbon atoms, hence a Tetradecanoic acid has many properties.
Tetradecanoic acid is a dark colored oil solid, a dark colored oil solid and a dark oil.
Tetradecanoic acid and monolaurin have significantly significant antimicrobial activity against gram positive bacteria and a number of fungi and viruses.
Today, there are many commercial products that use Tetradecanoic acid and monolaurin as antimicrobial agents.
Because of the significant differences in Tetradecanoic acid properties compared to longer chain fatty acids, they are typically divided into medium chain fatty acids covering C6 - C12 and long chain fatty acids covering C14 and longer.
Coconut oil is all the rage in natural beauty and wellness regimens.
Numerous blogs and natural health websites have come out as a miracle product and have been able to do anything to relieve chapped skin.
However, when you break down coconut oil into Tetradecanoic acid active parts, things start to look less miraculous and more like science.
Tetradecanoic acid is one of those active parts.
Tetradecanoic acid is a medium-length long-chain fatty acid or lipid that makes up about half of the fatty acids in coconut oil.
Tetradecanoic acid is often used in lab research of melting point depression Used, inexpensive, non-toxic and safe to use.
Tetradecanoic acid is a solid at room temperature but dissolves easily in boiling water, so liquid Tetradecanoic acid can be processed with a variety of solutes and used to determine their molecular mass.
Tetradecanoic acid is a fatty acid obtained from coconut oil and other veg- etable fats.
Tetradecanoic acid is practically insoluble in water but is soluble in alco- hol, chloroform, and ether.
Tetradecanoic acid functions as a lubricant, binder, and defoaming agent.
Tetradecanoic acid is a carboxylic acid.
Carboxylic acids donate hydrogen ions if a base is present to accept them.
They react in this way with all bases, both organic (for example, the amines) and inorganic.
Their reactions with bases, called "neutralizations'', are accompanied by the evolution of substantial amounts of heat.
Neutralization between an acid and a base produces water plus a salt.
Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt.
Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry.
Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in Tetradecanoic acid to corrode or dissolve iron, steel, and aluminum parts and containers.
Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide.
The reaction is slower for dry, solid carboxylic acids.
Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide.
Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides.
Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionite (SO2), to generate flammable and/or toxic gases and heat.
Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat.
Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents.
These reactions generate heat.
Like other acids, carboxylic acids may initiate polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions.
Tetradecanoic acid can react with oxidizing materials.
Some surfactants of the derivatives of dodecanoic acid and dodecanol are also antiseptics, such as dodecyl dimethyl benzyl ammonium chloride (geramine), dodecyl dimethyl benzyl ammonium bromide (bromo-geramine) and dodecyl dimethyl (2-phenoxyethyl) ammonium bromide (domiphen bromide).
The dodecyldimethyllammonium-2,4,5-trichlorophenolate in these derivatives can be used as citrus preservative.
Tetradecanoic acid also has many applications in plastic additives, food additives, spices and pharmaceutical industries.
Tetradecanoic acid (C-12) is very common in nature.
Which is a type of monoglyceride when Tetradecanoic acid enters the body converted to monolaurin.
Monolaurin; antiviral, antimicrobial, antiprotozoal and antifungal Tetradecanoic acid is a substance that stands out with Tetradecanoic acid features.
Tetradecanoic acid is a saturated fatty acid with a chain of 12 carbon atoms, hence Tetradecanoic acid has many properties of medium chain fatty acids, Tetradecanoic acid is a dark fatty solid and a dark fatty solid and a dark oil.
Salts and esters of Tetradecanoic acid are known as laureates.
Tetradecanoic acids chemical formula is CH3 (CH2) 1 (/ 0) COOH.
Intermediates of Liquid Crystals:
Given Tetradecanoic acids foaming properties, the derivatives of Tetradecanoic acid is widely used as a base in the manufacture of soaps, detergents, and lauryl alcohol.
Tetradecanoic acid is a common constituent of vegetable fats, especially coconut oil and laurel oil.
Tetradecanoic acid may have a synergistic effect in a formula to help fight against mircoorganisms.
Tetradecanoic acid is a mild irritant but not a sensitizer, and some sources cite Tetradecanoic acid as comedogenic.
Tetradecanoic acid is a fatty acid obtained from coconut oil and other veg- etable fats.
Tetradecanoic acid is practically insoluble in water but is soluble in alco- hol, chloroform, and ether.
Tetradecanoic acid functions as a lubricant, binder, and defoaming agent.
Applications of Tetradecanoic acid:
Tetradecanoic acid is mainly used in the manufacturing of soaps and other cosmetics.
In scientific laboratories, Tetradecanoic acid is often used to investigate the molar mass of unknown substances via freezing-point depression.
In industry, Tetradecanoic acid is used as an intermediate and as a surface active agent.
The consumer market uses Tetradecanoic acid in the cleaning, furnishing, and production of personal care products.
In medicine, Tetradecanoic acid is known to increase total serum cholesterol more than many of the other fatty acids.
Tetradecanoic acid uses include acid chlorides, amphoteric surfactant intermediate, anti ageing creams & lotions, antiperspirants, bar soap, betaines, body wash, cosmetics, deodorants, emollient, emulsifier, exfoliant scrub, facial cleaner, foundations, glycerol esters, hair care, hair colorants, imidazolines, lip balm, liquid hand soap, lubricant, moisturizing cream formulations, organic peroxides, sarcosinates, shaving cream, shower gels, skin care products, etc.
Treatment for intestinal infections and ringworm caused by the parasite.
Tetradecanoic acid in foods is used as a vegetable abbreviation.
In manufacturing, Tetradecanoic acid is used to make soap and shampoo.
Tetradecanoic acid is not known how Tetradecanoic acid works as a medicine.
Some research suggests that Tetradecanoic acid may be a safer oil than trans fats in food preparations.
Pharmaceutical Applications:
Tetradecanoic acid has also been examined for use as an enhancer for topical penetration and transdermal absorption, rectal absorption, buccal delivery, and intestinal absorption.
Tetradecanoic acid is also useful for stabilizing oil-in-water emulsions.
Tetradecanoic acid has also been evaluated for use in aerosol formulations.
Uses of Tetradecanoic acid:
Tetradecanoic acid Used for the preparation of alkyd resins, as well as wetting agents, detergents and pesticides
Tetradecanoic acid is used for peeling vegetables and fruits with a maximum amount of 3.0g/kg.
Tetradecanoic acid is used as defoamer; GB 2760-86 provides for the spices allowed to use; used for the preparation of other food grade additives.
Tetradecanoic acid is widely used in the surfactant industry and can be, according to the classification of surfactants, divided into cationic, anionic, non-ionic and amphoteric type.
Some surfactants of the derivatives of dodecanoic acid and dodecanol are also antiseptics, such as dodecyl dimethyl benzyl ammonium chloride (geramine), dodecyl dimethyl benzyl ammonium bromide (bromo-geramine) and dodecyl dimethyl (2-phenoxyethyl) ammonium bromide (domiphen bromide).
The dodecyldimethyllammonium-2,4,5-trichlorophenolate in these derivatives can be used as citrus preservative.
Tetradecanoic acid also has many applications in plastic additives, food additives, spices and pharmaceutical industries.
Consumer Uses:
Tetradecanoic acid is used in the following products: washing & cleaning products, coating products, fillers, putties, plasters, modelling clay, finger paints, polishes and waxes, air care products and plant protection products.
Other release to the environment of Tetradecanoic acid is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Other Consumer Uses:
Cleaning and furnishing care products,
Cleaning compound,
Floor coverings,
Industrial organic chemicals used in commercial and consumer products,
Lubricants and greases,
Personal care products.
Industry Uses:
Tetradecanoic acid is used in the following products: washing & cleaning products, leather treatment products, polymers, textile treatment products and dyes, pH regulators and water treatment products and lubricants and greases.
Tetradecanoic acid is used in the following areas: formulation of mixtures and/or re-packaging and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Tetradecanoic acid is used for the manufacture of: textile, leather or fur.
Release to the environment of Tetradecanoic acid can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid and as processing aid.
Other Industry Uses:
Commercial and industrial products,
Dyes,
Intermediates.
Widespread uses by professional workers:
Tetradecanoic acid is used in the following products: washing & cleaning products, polishes and waxes, adhesives and sealants, cosmetics and personal care products and laboratory chemicals.
Tetradecanoic acid is used in the following areas: formulation of mixtures and/or re-packaging and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Tetradecanoic acid is used for the manufacture of: textile, leather or fur.
Release to the environment of Tetradecanoic acid can occur from industrial use: formulation of mixtures and in processing aids at industrial sites.
Other release to the environment of Tetradecanoic acid is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Biocidal Uses:
Tetradecanoic acid is approved for use as a biocide in the EEA and/or Switzerland, for: repelling or attracting pests.
For Acne Uses:
Because Tetradecanoic acid has antibacterial properties, Tetradecanoic acid been found to effectively combat acne.
The bacteria Propionibacterium acnes are found naturally on the skin.
When they overgrow, they lead to the development of acne.
The results of a 2009 study found that Tetradecanoic acid could reduce inflammation and the number of bacteria present.
Tetradecanoic acid worked even better than benzoyl peroxide, a common acne treatment.
A 2016 study also reconfirmed the acne-fighting properties of Tetradecanoic acid.
This doesn’t mean you should put coconut oil on your acne.
The researchers used pure Tetradecanoic acid and suggested that Tetradecanoic acid could be developed into an antibiotic therapy for acne in the future.
Laboratory uses:
In the laboratory, Tetradecanoic acid may be used to investigate the molar mass of an unknown substance via the freezing-point depression.
The choice of Tetradecanoic acid is convenient because the melting point of the pure compound is relatively high (43.8°C).
Tetradecanoic acid cryoscopic constant is 3.9°C·kg/mol.
By melting Tetradecanoic acid with the unknown substance, allowing Tetradecanoic acid to cool, and recording the temperature at which the mixture freezes, the molar mass of the unknown compound may be determined.
Other Uses:
Plastics:
In plastics manufacturing applications, Tetradecanoic acid serves as an intermediate, which is substance formed during the middle stages of a chemical reaction between the reactants and the finished product.
Food and Beverage:
One of the more common uses of Tetradecanoic acid is as raw material for emulsifiers in various food and beverage additives, particularly in the manufacturing of vegetable shortening.
Tetradecanoic acids nontoxicity also makes Tetradecanoic acid safe for use in food production.
Surfactants and Esters:
When used as anionic and nonionic surfactants, Tetradecanoic acid has the ability to reduce surface tension between liquids and solids.
Textiles:
Tetradecanoic acid works well as a lubricant & process agent in textile manufacturing applications, as Tetradecanoic acid has the ability to help water mix with oil.
Personal Care:
One of the more common Tetradecanoic acid uses is as an emulsifier for facial creams and lotions, as Tetradecanoic acid possesses a strong ability to cleanse skin and hair.
Tetradecanoic acid is also easy to wash away after use.
You can find Tetradecanoic acid in many personal care products such as shampoos, body washes and shower gels.
Soaps and Detergents:
When used as a base in the production of liquid and transparent soaps, Tetradecanoic acid can control the level of lathering, add conditioning properties and enhance overall cleaning ability.
Medical:
Tetradecanoic acid can be found in a variety of medicines used for treating viral infections, certain forms of influenza, fever blisters, cold sores, bronchitis, yeast infections, gonorrhea, genital herpes and many others.
However, there is insufficient evidence to determine Tetradecanoic acid overall effectiveness in treating these conditions.
Preliminary research also indicates that Tetradecanoic acid may aid in the treatment of acne as well.
Tetradecanoic acid, is the main acid in coconut oil and in palm kernel oil, and is believed to have antimicrobial properties.
The detected values of half maximal effective concentration (EC(50)) of Tetradecanoic acid on P. acnes, S. aureus, and S. epidermidis growth indicate that P. acnes is the most sensitive to Dodecanoic Acid among these bacteria.
In addition, Tetradecanoic acid did not induce cytotoxicity to human sebocytes.
This data highlight the potential of using Tetradecanoic acid as an alternative treatment for antibiotic therapy of acne vulgaris.
Tetradecanoic acid is used in the manufacture of soaps, detergents, cosmetics, and lauryl alcohol.
Cleansing:
Helps to keep a clean surface
Emulsifying:
Promotes the formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil)
Surfactant:
Reduces the surface tension of cosmetics and contributes to the even distribution of the product when Tetradecanoic acid is used
Diet With Tetradecanoic acid:
Tetradecanoic acid can be taken as a supplement, but Tetradecanoic acid is most commonly consumed as part of coconut oil or palm kernel oil.
Tetradecanoic acid is considered to be safe based on the amounts generally found in food.
However, because they are still pure oil, limit your intake of MCTs to stay within the recommended 5 to 7 teaspoons of oil per day as set out by the U.S. Department of Agriculture.
You can use coconut and palm kernel oil for stir-fries because both oils withstand high heat.
They can also be used in baking, adding a natural richness to your food.
Chemical properties of Tetradecanoic acid:
Tetradecanoic acid is colorless needle-like crystals.
Tetradecanoic acid is soluble in methanol, slightly soluble in acetone and petroleum ether.
Like many other fatty acids, Tetradecanoic acid is inexpensive, has a long shelf-life, and is non-toxic and safe to handle.
Tetradecanoic acid is mainly used for the production of soaps and cosmetics.
For these purposes, Tetradecanoic acid is neutralized with sodium hydroxide to give sodium laurate, which is a soap.
Most commonly, sodium laurate is obtained by saponification of various oils, such as coconut oil. These precursors give mixtures of sodium laurate and other soaps.
Tetradecanoic acid occurs as a white crystalline powder with a slight odor of bay oil.
Tetradecanoic acid is a white solid with a faint odour of bay oil
Tetradecanoic acid has a fatty odor.
Tetradecanoic acid is a common constituent of most diets; large doses may produce gastrointestinal upset
Potential medicinal properties:
Tetradecanoic acid increases total serum cholesterol more than many other fatty acids, but mostly high-density lipoprotein (HDL) (the "good" blood cholesterol).
As a result, Tetradecanoic acid has been characterized as having "a more favorable effect on total HDL cholesterol than any other fatty acid, either saturated or unsaturated".
In general, a lower total/HDL serum cholesterol ratio correlates with a decrease in atherosclerotic risk.
Nonetheless, an extensive meta-analysis on foods affecting the total LDL/serum cholesterol ratio found in 2003 that the net effects of Tetradecanoic acid on coronary artery disease outcomes remained uncertain.
A 2016 review of coconut oil (which is nearly half Tetradecanoic acid) was similarly inconclusive about the effects on cardiovascular disease risk.
Production methods of Tetradecanoic acid:
Industrial production methods of Tetradecanoic acid can be grouped into two categories:
1) Derived from the saponification or high temperature and pressure decomposition of natural vegetable oils and fats;
2) Separated from the synthetic fatty acid.
Japan mainly uses coconut oil and palm kernel oil as the raw materials for the preparation of Tetradecanoic acid.
The natural vegetable oils used to produce Tetradecanoic acid include coconut oil, litsea cubeba kernel oil, palm kernel oil and mountain pepper seed oil.
Other plants oil, such as palm kernel oil, tea tree seed oil and camphor tree seed oil, can also service industry to produce Tetradecanoic acid.
The residual C12 distillate from the extraction of Tetradecanoic acid, containing a large number of dodecenoic acid, can be hydrogenated at atmospheric pressure, without catalyst, to convert into Tetradecanoic acid with a yield of more than 86%.
Tetradecanoic acid derived from the separation and purification of coconut oil and other vegetable oil.
Tetradecanoic acid naturally exists in coconut oil, litsea cubeba kernel oil, palm kernel oil and pepper kernel oil in the form of glyceride.
Tetradecanoic acid can be derived from the hydrolysis of natural oils and fats in industry.
The coconut oil, water and catalyst are added into the autoclave and hydrolyzed to glycerol and fatty acid at 250 ℃ under the pressure of 5MPa.
The content of Tetradecanoic acid is 45%~80%, and can be further distilled to obtain dodecanoic acid.
Tetradecanoic acid is a fatty carboxylic acid isolated from vegetable and animal fats or oils.
For example, coconut oil and palm kernel oil both contain high proportions of Tetradecanoic acid.
Isolation from natural fats and oils involves hydrolysis, separation of the fatty acids, hydrogenation to convert unsaturated fatty acids to saturated acids, and finally distillation of the specific fatty acid of interest.
Manufacture of Tetradecanoic acid:
Release to the environment of Tetradecanoic acid can occur from industrial use: manufacturing of Tetradecanoic acid.
Industry Processing Sectors:
All other basic organic chemical manufacturing,
All other chemical product and preparation manufacturing,
Petroleum lubricating oil and grease manufacturing,
Plastic material and resin manufacturing,
Soap, cleaning compound, and toilet preparation manufacturing,
Synthetic dye and pigment manufacturing,
Textiles, apparel, and leather manufacturing.
Occurrence of Tetradecanoic acid:
Tetradecanoic acid, a component of triglycerides, makes up about half the fatty acid content in coconut milk, coconut oil, laurel oil, and palm kernel oil (not to be confused with palm oil), otherwise, Tetradecanoic acid is relatively rare.
Tetradecanoic acid is also found in breast milk (6.2% of total fat), cow's milk (2.9%) and goat's milk (3.1%).
Tetradecanoic acid is one of these active parts.
Tetradecanoic acid is a medium-length long-chain fatty acid or lipid that makes up about half of the fatty acids in coconut oil.
Tetradecanoic acid is a potent substance sometimes extracted from coconut for use in developing monolaurin.
Monolaurin, bacteria, Tetradecanoic acid is an antimicrobial agent that can fight pathogens such as viruses and yeasts.
You cannot digest Tetradecanoic acid alone, as Tetradecanoic acid is irritating and does not occur alone in nature.
You are most likely to get Tetradecanoic acid in the form of coconut oil or fresh coconut.
While coconut oil is being studied at breakthrough speed, most of the research does not pinpoint exactly what is responsible for the oil's reported benefits.
Since coconut oil contains a lot more than Tetradecanoic acid, Tetradecanoic acid would be too long to credit Dodecanoic Acid with all the benefits of coconut oil.
Still, a 2015 analysis suggested that most of the benefits linked to coconut oil were directly attributed to Tetradecanoic acid.
They suggest that Tetradecanoic acid may aid weight loss and protect against Alzheimer's disease, among other benefits.
The effects on blood cholesterol levels still need to be cl.
Tetradecanoic acid, as a component of triglycerides, comprises about half of the fatty-acid content in coconut milk, coconut oil, laurel oil, and palm kernel oil (not to be confused with palm oil), Otherwise, Tetradecanoic acid is relatively uncommon.
Tetradecanoic acid is also found in human breast milk (6.2% of total fat), cow's milk (2.9%), and goat's milk (3.1%).
Like many other fatty acids, Tetradecanoic acid is inexpensive, has a long shelf-life, is nontoxic, and is safe to handle.
Tetradecanoic acid is used mainly for the production of soaps and cosmetics.
For these purposes, Tetradecanoic acid is reacted with sodium hydroxide to give sodium laurate, which is a soap.
Most commonly, sodium laurate is obtained by saponification of various oils, such as coconut oil.
These precursors give mixtures of sodium laurate and other soaps.
Storage of Tetradecanoic acid:
Tetradecanoic acid is stable at normal temperatures and should be stored in a cool, dry place.
Avoid sources of ignition and contact with incompatible materials.
Identifiers of Tetradecanoic acid:
CAS Number: 143-07-7
CHEBI:30805
ChEMBL: ChEMBL108766
ChemSpider: 3756
ECHA InfoCard: 100.005.075
EC Number: 205-582-1
IUPHAR/BPS: 5534
KEGG: C02679
PubChem CID: 3893
UNII: 1160N9NU9U
CompTox Dashboard (EPA): DTXSID5021590
Properties of Tetradecanoic acid:
Chemical formula: C12H24O2
Molar mass: 200.322 g·mol−1
Appearance: White powder
Odor: Slight odor of bay oil
Density:
1.007 g/cm3 (24 °C)
0.8744 g/cm3 (41.5 °C)
0.8679 g/cm3 (50 °C)
Melting point: 43.8 °C (110.8 °F; 316.9 K)
Boiling point:
297.9 °C (568.2 °F; 571.0 K)
282.5 °C (540.5 °F; 555.6 K) at 512 mmHg
225.1 °C (437.2 °F; 498.2 K) at 100 mmHg
Solubility in water:
37 mg/L (0 °C)
55 mg/L (20 °C)
63 mg/L (30 °C)
72 mg/L (45 °C)
83 mg/L (100 °C)
Solubility: Soluble in alcohols, diethyl ether, phenyls, haloalkanes, acetates
Solubility in methanol:
12.7 g/100 g (0 °C)
120 g/100 g (20 °C)
2250 g/100 g (40 °C)
Solubility in acetone:
8.95 g/100 g (0 °C)
60.5 g/100 g (20 °C)
1590 g/100 g (40 °C)
Solubility in ethyl acetate:
9.4 g/100 g (0 °C)
52 g/100 g (20°C)
1250 g/100 g (40°C)
Solubility in toluene:
15.3 g/100 g (0 °C)
97 g/100 g (20°C)
1410 g/100 g (40°C)
log P 4.6
Vapor pressure:
2.13·10−6 kPa (25 °C)
0.42 kPa (150 °C)
6.67 kPa (210 °C)
Acidity (pKa):5.3 (20 °C)
Thermal conductivity:
0.442 W/m·K (solid)
0.1921 W/m·K (72.5 °C)
0.1748 W/m·K (106 °C)
Refractive index (nD):
1.423 (70 °C)
1.4183 (82 °C)
Viscosity:
6.88 cP (50 °C)
5.37 cP (60 °C)
Names of Tetradecanoic acid:
Regulatory process names:
Dodecanoic acid
Lauric acid
Lauric Acid
Lauric acid
lauric acid
Translated names:
Acid lauric (ro)
Acide laurique (fr)
Acido laurico (it)
Aċidu lawriku (mt)
Ido láurico (pt)
Kwas laurynowy (pl)
Kyselina dodekánová (sk)
Lauric acid (no)
Lauriinhape (et)
Lauriinihappo (fi)
Laurinezuur (nl)
Laurinsav (hu)
Laurinska kiselina (hr)
Laurinsyra (sv)
Laurinsyre (da)
Laurinsäure (de)
Laurová kyselina (cs)
Laurīnskābe (lv)
Lavrinska kislina (sl)
Uro rūgštis (lt)
Ácido láurico (es)
Λαυρικό οξύ (el)
Додеканова киселина (bg)
CAS name:
Dodecanoic acid
IUPAC names:
1-Dodecansäure
docecanoic acid
DODECANOIC ACID
Dodecanoic Acid
Dodecanoic acid
dodecanoic acid
Lauric Acid
Lauric acid
lauric acid
Lauric Acid
Lauric acid
lauric acid
Laurinic acid
Laurinsäure
n-Dodecanoic acid
Trade names:
DODECANOIC ACID
KORTACID 1299/ 1298/ 1295
Lauric Acid
MASCID 1298
MASCID 1299
PALMAC 98-12
PALMAC 99-12
Palmata 1299
PALMERA
RADIACID 0653
SINAR - FA1299
Tefacid Lauric 98
UNIOLEO FA 1299
Other identifiers:
143-07-7
203714-07-2
203714-07-2
7632-48-6
7632-48-6
8000-62-2
8000-62-2
8045-27-0
8045-27-0